- Preventive Vitamin D Supplementation and Risk for COVID-19 Infection: A Systematic Review and Meta-Analysis
- Vitamin D Life – COVID-19 treated by Vitamin D - studies, reports, videos
- Vitamin D Life -
43 studies in both Virus and Vitamin D intervention categories - VitaminDwiki COVID infections and vaccinations decrease Vitamin D – many studies
Preventive Vitamin D Supplementation and Risk for COVID-19 Infection: A Systematic Review and Meta-Analysis
Nutrients 2024, 16(5), 679; https://doi.org/10.3390/nu16050679
Marina Sartini 1,2,*,†ORCID,Filippo Del Puente 3,*,†,Martino Oliva 1,Alessio Carbone 1,Nicoletta Bobbio 3,Elisa Schinca 1,2,Luana Giribone 1 and Maria Luisa Cristina 1,2
1 Department of Health Sciences, University of Genoa, 16132 Genoa, Italy
2 Operating Unit Hospital Hygiene, Galliera Hospital, 16128 Genoa, Italy
3 Department of Infectious Diseases, Galliera Hospital, 16128 Genoa, ItalyOver the past few decades, vitamin D has been found to play a crucial role in bone homeostasis, muscle function, oncogenesis, immune response and metabolism. In the context of the COVID-19 pandemic, numerous researchers have tried to determine the role vitamin D might play in the immune response to the virus. The aim of this systematic review and meta-analysis is to demonstrate that preventive vitamin D supplementation can play a protective role in the incidence of COVID-19, mortality and admission to intensive care units (ICUs). A comprehensive search on the PubMed/MEDLINE, Scopus, Cochrane and Google Scholar databases was performed on 15 May 2023, and two of the authors independently screened the literature. As effect measures, we calculated the Odds Ratios with their corresponding 95% confidence intervals (ICs). The assessment of potential bias and the evaluation of study quality will be conducted independently by two researchers. Sixteen publications were selected for inclusion in the meta-analysis. Our findings indicate that vitamin D supplementation has a protective effect against the incidence of COVID-19 in RCT studies (OR 0.403, 95% IC 0.218, 0.747), in the incidence of COVID-19 in analytical studies (OR = 0.592, 95% IC 0.476–0.736) and in ICU admission (OR 0.317, 95% IC 0.147–0.680). Subsequent analyses were conducted by type of subject treated (patient/healthcare workers) and type of supplementation (vitamin D vs. placebo/no treatment or high dose vs. low dose). Our meta-analysis suggests a definitive and significant association between the protective role of vitamin D and COVID-19 incidence and ICU admission.
Download the PDF from Vitamin D LifeThis study was reported on in a Dr. Campbell video March 13, 2024
Vitamin D Life – COVID-19 treated by Vitamin D - studies, reports, videos
As of March 31, 2024, the Vitamin D Life COVID page had: trial results, meta-analyses and reviews, Mortality studies see related: Governments, HealthProblems, Hospitals, Dark Skins, All 26 COVID risk factors are associated with low Vit D, Fight COVID-19 with 50K Vit D weekly Vaccines Take lots of Vitamin D at first signs of COVID 166 COVID Clinical Trials using Vitamin D (Aug 2023) Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
5 most-recently changed Virus entries
- The above image is automatically updated
Vitamin D Life -
43 studies in both Virus and Vitamin D intervention categories This list is automatically updated
- 5 X less COVID infection of health care workers who took lots of vitamin D – meta-analysis Feb 2024
- COVID deaths cut in half by a single dose of 600,000 IU of Vitamin D - RCT Jan 2024
- COVID in hospital stopped by Vitamin D Receptor activators (curcumin, quercetin) – RCT June 2023
- Vitamin D Supplements Don’t Reduce COVID-19 Risk (used only 3,200 IU daily) - Oct 2022
- High dose vitamin D fights Folate gene changes by COVID, autoimmune, CVD, ALZ – Oct 2022
- COVID in hospital fought by Vitamin D (25,000 IU daily for 4 days, then 25K weekly) - RCT – July 2022
- Small Vitamin D doses for a short time never help (not improve vaccination in this case) – RCT Sept 2022
- The challenges of a Vitamin D RCT – too many already taking it, etc. – Martineau Sept 2022
- Early COVID treatments rarely work 7 days after symptoms, this trial gave Vitamin D on 7th day – RCT May 2022
- COVID children helped by Vitamin D, trial terminated: unethical to not give Vitamin D to all: – RCT July 2022
- COVID hospital deaths reduced 2X by 8 days of UVB – pilot RCT May 2022
- 21 fewer days in hospital with ARDS (COVID) if 10,000 IU of Vitamin D daily after enter hospital – RCT April, 2022
- 4X less likely to get COVID following 4,000 IU daily for a month – RCT April 2022
- Risk of COVID not reduced by 3,200 IU of vitamin D during 6 months (no surprise) – RCT March 2022
- Group achieving 30 ng (vs 26 ng) were 2X less likely to get COVID symptoms - RCT Jan 2022
- Tested positive for COVID, taking probiotics stopped symptoms 5 days sooner - RCT Jan 2022
- Vitamin D given slowly in hospital did not fight COVID-19 much - Nov 2021
- Nursing home vaccinated against Influenza, 800 IU of vitamin D daily cut infection rate in half – small RCT Oct 2021
- COVID-19 appears reduced by Resveratrol plus 100K IU of vitamin D – Small RCT Sept 2021
- Vitamin D trial for COVID-19 – using their patented slow-release form – Aug 2021
- COVID-19 mortality reduced 4X (chart looks like 2X) by large, infrequent doses of Vitamin D in France – July 2021
- COVID-19 outpatients getting Quercetin nanoemulsion had excellent outcomes (Q increased Vitamin D in cells) – RCT – June 2021
- 5,000 U daily raised Vitamin D a bit and helped COVID-19 a bit – RCT June 2021
- COVID-19 inflammation extinguished by 60,000 IU of vitamin D nanoemulsion daily for a week – RCT May 2021
- Better response to shingles virus after 6,400 IU Vitamin D raised above 40 ng – Jan 2021
- COVID-19 ICU survival rate increased 7X by daily Omega-3 – RCT March 2021
- Kidney patients who happened to be getting high-dose Calcitriol were 9X less likely to die of COVID-19 - April 6, 2021
- Vitamin D not help 10 days after COVID-19 symptoms - RCT March 2021
- 5X less likely to enter ICU with COVID-19 if get Calcifediol (semi-activated vitamin D) - RCT Feb 19, 2021
- calcifediol rct
- COVID-19 defeated 3x faster by 420,000 IU Vitamin D nanoemulsion – RCT Nov 12, 2020
- COVID-19 defeated by calcifediol form of Vitamin D in Spain - pilot RCT Aug 29, 2020
- Swine flu not prevented by 2,000 IU of vitamin D daily (the upper limit at the time) – RCT 2014
- Influenza vaccine antibodies not change with Vitamin D – 21 ng or 44 ng – RCT Feb 2019
- Dengue virus prevented by a small amount of Vitamin D – RCT Nov 2019
- Half the risk of Influenza -A in infants taking 1200 IU of vitamin D for 4 months – RCT Jan 2018
- Chikungunya virus arthritis pain reduced by weekly 60,000 IU vitamin D – Sept 2016
- Many Infectious diseases (virus) treated and prevented by Vitamin D – review July 2009
- Influenza prevented by 40 ng levels or treated with vitamin D hammer (50,000 IU) – June 2015
- Infection fighting ability increased with 5,000 IU Vitamin D daily – April 2015
- Vitamin D prevents Hepatitis-C and helps treat it (many studies)
- Malaria in mice brains, and associated inflammation, prevented by Vitamin D intervention – July 2014
- Influenza A: 5X reduction in first month (only) with 2,000 IU of vitamin D– RCT July 2014
VitaminDwiki COVID infections and vaccinations decrease Vitamin D – many studies
Vaccination
- COVID vaccinations resulted in big increase in metabolic disorders - Nov 2023
- COVID vaccination health problems - Campbell, Yale Nov 2023
- Hypothesis: Multiple COVID vaccinations reduce Vitamin D, resulting in Excess Deaths, etc. - Oct 2023
- Following COVID vaccination 31% had neurological problems (Italy) – Oct 2023
- Autoimmune diseases caused in first day after COVID Vaccination - Oct 2023
- Immune System tolerance is inversely related to the number of COVID vaccinations (PubMed analysis) - Oct 2023
- Hospital utilization Australia (NSW) 1415 Vaccinated, 0 unvaccinated - Dec 2022
- Vaccinated children have more health problems – any vaccination, not just COVID
- Multiple COVID vaccinations might increase Cancer Incidence - many studies
- Vaccine Clinical Trial - cardiovascular death 3.7X more likely if vaccinated - preprint Sept 2023
- Myocarditis, Pericarditis 2X more likely if had COVID vaccination in previous 30 days - meta-analysis June 2023
- COVID Vaccinations increased risk of cardiac deaths in youths by 19% - Aug 2023
- 800x Higher Incidence of Myocardial Injury After Booster Vaccination - July 2023
- 74% of autopsies were found to be related to COVID vaccination (from 44 studies) – Lancet July 2023
- More psoriasis flares following second COVID vaccination if lowish Vitamin D – May 2023
- Long-COVID 2.2X more-likely if had 2 COVID vaccinations - Dec 2022
Vaccination and/or Infection
- COVID infections or vaccinations may increase Multiple Sclerosis (if low D) - several studies
- 50% increase in Cancer deaths (age 15-44) since before COVID - Nov 2023
- Early puberty during pandemic (low vitamin D) - several studies
- Excess deaths - 5 possible reasons - many studies
- Low heart rate variability (bad) is associated with low Vitamin D and COVID – many studies
- T1 Diabetes increased by 27% by second year of COVID – meta-analysis June 2023
- Hepatitis normally rare in children: huge increase after lockdown (Adenovirus, low Vitamin D) - April 2022
- Increased risk of many neuro problems after COVID (1.4 X youths, 1.2X seniors) – Aug 2022
- COVID increased seniors risk of Alzheimer's by 1.7X in the next year- Sept 2022
- Increase in children with low vitamin D and with tibia fractures during COVID – June 2022
- Athletes who had been COVID infected had lower Vitamin D levels – July 2023
- COVID, Vitamin D, Drs. Grimes and Campbell - Jan 2024 has the following chart
Hypothesis: The body consumes Vitamin D each time the immune system is activated
The "GREEN" person started with a high level of Vitamin D
This assumes no vitamin D supplementation by supplements, sun, etc.5 X less COVID infection of health care workers who took lots of vitamin D – meta-analysis Feb 2024Printer Friendly Follow this page for updates456 visitors, last modified 13 Mar, 2024, This page is in the following categories (# of items in each category)