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- Pilot Phase Results of a Prospective, Randomized Controlled Trial of Narrowband Ultraviolet B Phototherapy in Hospitalized COVID-19 Patients
- Vitamin D Life -
14 studies in both categories Virus and UV - Vitamin D Life – COVID-19 treated by Vitamin D - studies, reports, videos
- Virus category is associated with 37 other Vitamin D Life categories
Pilot Phase Results of a Prospective, Randomized Controlled Trial of Narrowband Ultraviolet B Phototherapy in Hospitalized COVID-19 Patients
Exp Dermatol . 2022 May 31. doi: 10.1111/exd.14617
Frank H Lau 1, Catherine E Powell 1, Giacomo Adonecchi 2, Denise M Danos 3, Andrew R DiNardo 4, Robert J Chugden 5, Peter Wolf 6, Carmen F Castilla 7
Background: COVID-19 morbidity and mortality are driven by poor immune regulation. Narrowband ultraviolet B (NB-UVB) phototherapy is standard of care in a number of immune-dysregulated diseases. To assess the efficacy of NB-UVB phototherapy for improving COVID-19 outcomes in high-risk, hospitalized, we developed the Adaptive Photo-Protection Trial. This is a multi-center, prospective, double-blinded, randomized, placebo-controlled trial. The pilot phase results are reported here.Experimental design: Consecutive patients admitted with a positive COVID-19 PCR were screened for eligibility. Enrolled subjects were computer randomized 1:1 to NB-UVB or placebo phototherapy. Subjects were treated daily with escalating doses on 27% of their body surface area for up to 8 consecutive days. Primary outcomes were safety and efficacy, defined as persistent or painful erythema and 28-day mortality. Comparisons were made via non-parametric exact tests.
Results: Patients in treatment (n=15) and placebo (n=15) arms had similar demographics. No adverse events occurred. 28-day mortality was 13.3% in treatment vs. 33.3% in placebo arms (p=0.39).
Conclusions: NB-UVB phototherapy in hospitalized COVID-19 patients was safe. Decreased mortality was observed in treated patients but this was statistically non-significant. Given its low-cost, scalability, and adjunctive nature, NB-UVB has the potential to improve COVID-19 outcomes. Continuation of this trial is warranted.
 Download the PDF from Vitamin D LifePossible reason: Vitamin D generated in skin ==> fortified immune system
UVB might have generated 10,000 IU daily
21 fewer days in hospital with ARDS (COVID) if 10,000 IU of Vitamin D daily after enter hospital – RCT April, 2022
UV and COVID: Prevention and perhaps treatment
UVB phototherapy (which increases Vitamin D and VDR) decreased risk of many heart and stroke problems – July 2020Possible reason: Virus killed by UVB ==> stop re-infection
Ultraviolet light kills cold and flu viruses, and generates Vitamin D in the skin
Unlikely to be due to Nitric Oxide - as NO is generated by UVA, not UVB
See: Nitric oxide (from Sun, UVA, Vitamin D) reduces cardiovascular problems
Vitamin D Life -
14 studies in both categories Virus and UV This list is automatically updated
- COVID hospital deaths reduced 2X by 8 days of UVB – pilot RCT May 2022
- UV and COVID: Prevention and perhaps treatment
- 11 percent fewer COVID-19 deaths if lockdowns had allowed sunshine – Nov 2021
- COVID-19 deaths - 30 percent fewer if high UVA (US, etc) – Aug 2021
- 4th highest county in the US has a very low COVID-19 rate (high UV, high vitamin D)
- COVID-19 onset strongly associated with latitude in Europe (Vitamin D)– Jan 21, 2021
- UV provides the best explanation of COVID-19 variation in Italy (74 pcnt) – Nov 2020
- More UVB, less Coronavirus – including SARS-CoV-2 – Aug 2020
- Less COVID-19 at high altitude due to more Vitamin D or other possible reasons – July 2020
- Far fewer COVID-19 deaths in the summer (Europe, Canada)
- High-altitude Cusco, Peru has far lower rate of COVID-19 than others (high UVB and Vitamin D) - June 2020
- Influenza Virus aerosols killed by 10 minutes of sunlight (far faster if use UV-C) – Nov 2019
- Influenza Virus aerosols killed by 10 minutes of sunlight (faster if use UVB, UVCC– Nov 2019
- Ultraviolet light kills cold and flu viruses, and generates Vitamin D in the skin
Vitamin D Life – COVID-19 treated by Vitamin D - studies, reports, videos
As of July 6, 2022, the Vitamin D Life page had: 34 trials, 11 trial results, 37 meta-analyses and reviews, 69 observations, 38 recommendations, 55 associations, 89 speculations, 58 videos, 45 Mortality studies see related: Governments, HealthProblems, Hospitals, Dark Skins, 26 risk factors are ALL associated with low Vit D, Recent Virus pages Fight COVID-19 with 50K Vit D weekly Vaccines Take lots of Vitamin D at first signs of COVID COVID Clinical Trials (06/22) using Vit D: 114, Vit D & Zinc: 26, Calcidiol: 26
Virus category is associated with 37 other Vitamin D Life categories
Click here Examples include: Zinc, Vitamin D Receptor, Magnesium, Omega-3, Vitamin K. Intervention - non-daily
COVID hospital deaths reduced 2X by 8 days of UVB – pilot RCT May 2022168 visitors, last modified 06 Jun, 2022, This page is in the following categories (# of items in each category)