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- Can Serum 25 hydroxy Vitamin D Levels Predict the Severity of Multisystem Inflammatory Syndrome in Children and COVID-19?
- Vitamin D Life -
56 studies in both categories Virus and Children Can Serum 25 hydroxy Vitamin D Levels Predict the Severity of Multisystem Inflammatory Syndrome in Children and COVID-19?
J Clin Res Pediatr Endocrinol . 2023 Feb 16. doi: 10.4274/jcrpe.galenos.2023.2022-10-1
Yildiz Ekemen Keles 1, Dilek Yilmaz 2, Selin Tasar 1, Gulnihan Ustundag 1, Aslihan Sahin 1, Aysegul Elvan Tuz 1, Aslihan Arslan Maden 1, Ahu Kara Aksay 1, Ayfer Colak 3, Eda Karadag Oncel 1Objective: To determine the clinical significance of serum 25 hydroxy (OH) vitamin D levels in pediatric patients with multisystem inflammatory syndrome (MIS-C) and compare the vitamin D levels of these patients with those patients with COVID-19 and healthy controls.
Methods: This study was designed for pediatric patients who were aged 1 month to 18 years between July 14 and December 25, 2021. Fifty-one patients with MIS-C, 57 who were hospitalized with COVID-19, and 60 controls were enrolled in the study. Vitamin D insufficiency was defined as a serum 25 OH vitamin D level of less than 20 ng/mL.
Results: The median serum 25 (OH) vitamin D was 14.6 ng/mL in patients with MIS-C, 16 ng/mL in patients with COVID-19, and 21.1 ng/mL in the control group (p<0.001). Vitamin D insufficiency was present in 74.5% (n=38) of patients with MIS-C, 66.7% (n=38) of patients with COVID-19, and 41.7% (n=25) of the controls (p=0.001). The percentage of four or more affected organ systems was 39.2% in patients with MIS-C. The correlation between the number of affected organ systems and serum 25 (OH) vitamin D levels was evaluated in patients with MIS-C and there was a moderate negative correlation (r= -0.310; p=0.027). A weak negative correlation was found between the severity of COVID-19 and serum 25 (OH) vitamin D (r= -0.320, p=0.015).
Conclusion: It was found that vitamin D levels were insufficient in both groups and correlated with the number of affected organ systems of MIS-C and the severity of COVID-19.
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56 studies in both categories Virus and Children This list is automatically updated
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- 18,000 schoolchildren in Canada to be suspended for not being vaccinated - Feb 2024
- COVID Vaccinated Children 1.25 X More Likely to Be Hospitalized for Respiratory Illness - CDC Jan 2024
- France has injected 200,000 infants with RSV vaccine, based on no long-term data - Here we go again - Dec 2023
- Brazil mandates COVID-19 vaccine for children - Nov 2023
- Doctors in NY cannot opt out of COVID boosters for children - Oct 2023
- Infants getting lots of vaccinations are 2X more likely to die - July 2023
- COVID, Long-COVID and Vitamin D in children - Review April 2023
- Multisystem Inflammatory Syndrome of COVID in Children 3X more likely if low Vitamin D – Feb 2023
- PICU layoffs due to pandemic lulls, but children are now getting 3 years of viral infection all at once – Oct 2022
- COVID 5.5 X more likely to be severe if low Vitamin D (children in this case) – Oct 2022
- Tripledemic: Flu, COVID, and RSV (all fought by Vitamin D) - Oct 2022
- CDC advised to recommended annual COVID vaccination of all children over 6 months old – Oct 20, 2022
- 6X increase in excess deaths of children since vaccinations were started - Oct 2022
- Early puberty during pandemic (low vitamin D) - several studies
- COVID kids were more likely to have a poor VDR (4.3 X), than low Vitamin D (2.6 X) – Sept 2022
- Recent increases in pediatric endocrine problems may be decreased by Vitamin D – Aug 2022
- COVID children helped by Vitamin D, trial terminated: unethical to not give Vitamin D to all: – RCT July 2022
- Increase in children with low vitamin D and with tibia fractures during COVID – June 2022
- 28,859 deaths and 238,412 serious injuries due to vaccines, how many more when add ages 0.5 - 5 – June 2022
- Pandemic Vitamin D levels dropped by 3.3 ng (perhaps less D, more health problems) – May 2022
- Problems after childhood vaccinations - many studies
- FDA approved 5-11 vaccine booster (based tiny unpublished study without asking advisory panel) May 2022
- Remdesivir approved to treat COVID in Infants, yet Vitamin D is 3000 X more cost effective and widely used - April 2022
- Risk factors for severe COVID in children are all related to low vitamin D (same as adults) - April 2022
- Hepatitis normally rare in children: huge increase after lockdown (Adenovirus, low Vitamin D) - April 2022
- Children with higher Vitamin D had less severe COVID (no surprise) – April 2022
- Children have less severe COVID, but just as much long-haul as adults - April 2022
- Croup (due to viruses) has surged with Omicron - March 2022
- COVID children with multisystem inflammatory syndrome have less than 10 ng of vitamin D – March 2022
- 16,000 Physicians and Scientists Agree Kids Shouldn’t Get COVID Vaccine - Dec 15, 2021
- Younger are much less likely to die of COVID than elderly (posters) - Nov 2021
- COVID Vaccination trial for kids: 11 red flags - Oct 25, 2021
- Children and COVID - many studies
- 8 of 10 pediatric COVID-19 infections were Vitamin D deficient (49 patients) – May 2021
- Severe pediatric COVID 5.5 more likely if low vitamin D (review of 6 studies) -July 2021
- Sudden Infant Deaths (SIDS) soon after vaccination - several studies
- Hospitalized children with COVID-19 and inflammation had lower vitamin D – March 2021
- Severe childhood COVID-19 associated with Vitamin D deficiency (hospital in Turkey) – March 2021
- Vitamin D might reduce Multisystem Inflammatory Syndrome in children – March 2021
- 87 percent of children with COVID–19 had low vitamin D (small study) – Feb 2021
- Vaccinations resulted in increased office visits for children 16 months later - Nov 2020
- 13 possible reasons why COVID-19 is less severe in children – Dec 1, 2020
- Vitamin D associated with reduced COVID-19 risks in children - Grassroots Nov 2020
- Children with low vitamin D far more likely to hospitalized with COVID-19 – Oct 2020
- Respiratory viral infection (RSV) and low vitamin D - many studies
- Increased weight in children 8X more likely for each unit increase in adenovirus (if ignore Vitamin D) – Nov 2019
- Severe hand, foot, and mouth virus is 2.9 X more likely if poor Vitamin D receptor – Oct 2018
- More US infants die in 1st day than in all other developed countries COMBINED (and US gives vaccine in first day) – May 2013
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