- Vitamin D Levels in COVID-19 and NonCOVID-19 Pediatric Patients and Its Relationship with Clinical and Laboratory Characteristics
- Vitamin D Life -
56 studies in both of the categories Infant-Child and Virus - Vitamin D Life -
9 studies in both of the categories Infant-Child and Iron Vitamin D Levels in COVID-19 and NonCOVID-19 Pediatric Patients and Its Relationship with Clinical and Laboratory Characteristics
Biomedicines 2024, 12, 905. https://doi.org/10.3390/biomedicines12040905
Maria Totan -1,2, Ioana-Octavia
Matacuta-Bogdan *, Adrian Hasegan and Ionela Maniu 3,4,*
Faculty of Medicine, Lucian Blaga University of Sibiu, 2A Lucian Blaga Str., 550169 Sibiu, Romania; maria.totan at ulbsibiu.ro (M.T.); adrian.hasegan at ulbsibiu.ro (A.H.)
Clinical Laboratory, Pediatric Clinical Hospital Sibiu, 2-4 Pompeiu Onofreiu Str., 550166 Sibiu, Romania
Research Team, Pediatric Clinical Hospital Sibiu, 550166 Sibiu, Romania
Research Center in Informatics and Information Technology, Mathematics and Informatics Department, Faculty of Sciences, Lucian Blaga University of Sibiu, 550025 Sibiu, Romania
25-hydroxyvitamin D [25(OH)D] is a marker with an important role in regulating the inflammatory response. Low concentrations of this vitamin are often found among the population, correlated with increased risk of respiratory tract infections. The aim of the study is to evaluate the relationship between vitamin D levels and clinical and laboratory markers in children and adolescents hospitalized with and without COVID-19. A retrospective study, including all patients tested for SARS-CoV-2 and having vitamin D measured, was performed. All included hospitalized cases, 78 COVID-19 patients and 162 NonCOVID-19 patients, were divided into subgroups according to their 25(OH)D serum levels (<20 ng/mL—deficiency, 20-30 ng/mL—insufficiency, >30 ng/mL—normal or <30 ng/mL, >30 ng/mL) and age (<2 years, >2 years). Vitamin D deficiency and insufficiency increased with age, in both COVID-19 and NonCOVID-19 groups. All symptoms were encountered more frequently in cases of pediatric patients with COVID-19 in comparison with NonCOVID-19 cases. The most frequently encountered symptoms in the COVID-19 group were fever, loss of appetite, and nasal congestion. In the NonCOVID-19 group, serum 25(OH)D concentrations were positively correlated with leukocytes, lymphocytes, and LMR and negatively correlated with neutrophils, NLR, and PLR while no significant correlation was observed in the case of COVID-19 group. Differences between vitamin D status and clinical and laboratory parameters were observed, but their clinical significance should be interpreted with caution. The results of this study may offer further support for future studies exploring the mechanisms of the relationship between vitamin D and clinical and laboratory markers as well as for studies investigating the implications of vitamin D deficiency/supplementation on overall health/clinical outcomes of patients with/without COVID-19.
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56 studies in both of the categories Infant-Child and Virus This list is automatically updated
- Children in hospital: those with COVID had lower Vitamin D, Iron, etc. – April 2024
- US has the most vaccinations before age 1 and the most deaths - March 2024
- 18,000 schoolchildren in Canada to be suspended for not being vaccinated - Feb 2024
- COVID Vaccinated Children 1.25 X More Likely to Be Hospitalized for Respiratory Illness - CDC Jan 2024
- France has injected 200,000 infants with RSV vaccine, based on no long-term data - Here we go again - Dec 2023
- Brazil mandates COVID-19 vaccine for children - Nov 2023
- Doctors in NY cannot opt out of COVID boosters for children - Oct 2023
- Infants getting lots of vaccinations are 2X more likely to die - July 2023
- COVID, Long-COVID and Vitamin D in children - Review April 2023
- Multisystem Inflammatory Syndrome of COVID in Children 3X more likely if low Vitamin D – Feb 2023
- PICU layoffs due to pandemic lulls, but children are now getting 3 years of viral infection all at once – Oct 2022
- COVID 5.5 X more likely to be severe if low Vitamin D (children in this case) – Oct 2022
- Tripledemic: Flu, COVID, and RSV (all fought by Vitamin D) - Oct 2022
- CDC advised to recommended annual COVID vaccination of all children over 6 months old – Oct 20, 2022
- 6X increase in excess deaths of children since vaccinations were started - Oct 2022
- Early puberty during pandemic (low vitamin D) - several studies
- COVID kids were more likely to have a poor VDR (4.3 X), than low Vitamin D (2.6 X) – Sept 2022
- Recent increases in pediatric endocrine problems may be decreased by Vitamin D – Aug 2022
- COVID children helped by Vitamin D, trial terminated: unethical to not give Vitamin D to all: – RCT July 2022
- Increase in children with low vitamin D and with tibia fractures during COVID – June 2022
- 28,859 deaths and 238,412 serious injuries due to vaccines, how many more when add ages 0.5 - 5 – June 2022
- Pandemic Vitamin D levels dropped by 3.3 ng (perhaps less D, more health problems) – May 2022
- Problems after childhood vaccinations - many studies
- FDA approved 5-11 vaccine booster (based tiny unpublished study without asking advisory panel) May 2022
- Remdesivir approved to treat COVID in Infants, yet Vitamin D is 3000 X more cost effective and widely used - April 2022
- Risk factors for severe COVID in children are all related to low vitamin D (same as adults) - April 2022
- Hepatitis normally rare in children: huge increase after lockdown (Adenovirus, low Vitamin D) - April 2022
- Children with higher Vitamin D had less severe COVID (no surprise) – April 2022
- Children have less severe COVID, but just as much long-haul as adults - April 2022
- Croup (due to viruses) has surged with Omicron - March 2022
- COVID children with multisystem inflammatory syndrome have less than 10 ng of vitamin D – March 2022
- 16,000 Physicians and Scientists Agree Kids Shouldn’t Get COVID Vaccine - Dec 15, 2021
- Younger are much less likely to die of COVID than elderly (posters) - Nov 2021
- COVID Vaccination trial for kids: 11 red flags - Oct 25, 2021
- Children and COVID - many studies
- 8 of 10 pediatric COVID-19 infections were Vitamin D deficient (49 patients) – May 2021
- Severe pediatric COVID 5.5 more likely if low vitamin D (review of 6 studies) -July 2021
- Sudden Infant Deaths (SIDS) soon after vaccination - several studies
- Hospitalized children with COVID-19 and inflammation had lower vitamin D – March 2021
- Severe childhood COVID-19 associated with Vitamin D deficiency (hospital in Turkey) – March 2021
- Vitamin D might reduce Multisystem Inflammatory Syndrome in children – March 2021
- 87 percent of children with COVID–19 had low vitamin D (small study) – Feb 2021
- Vaccinations resulted in increased office visits for children 16 months later - Nov 2020
- 13 possible reasons why COVID-19 is less severe in children – Dec 1, 2020
- Vitamin D associated with reduced COVID-19 risks in children - Grassroots Nov 2020
- Children with low vitamin D far more likely to hospitalized with COVID-19 – Oct 2020
- Respiratory viral infection (RSV) and low vitamin D - many studies
- Increased weight in children 8X more likely for each unit increase in adenovirus (if ignore Vitamin D) – Nov 2019
- Severe hand, foot, and mouth virus is 2.9 X more likely if poor Vitamin D receptor – Oct 2018
- More US infants die in 1st day than in all other developed countries COMBINED (and US gives vaccine in first day) – May 2013
Vitamin D Life -
9 studies in both of the categories Infant-Child and Iron This list is automatically updated
- Anemia 8X more likely in infants if low vitamin D – Sept 2023
- Early brain development helped by Iron, Iodine, Vitamin D, Omega-3. Zinc etc. – Oct 2021
- Vitamin D deficiency 2.5 X more likely in iron-deficient children – Dec 2018
- Anemia in children 3.5 X more likely if low vitamin D – March 2018
- Autistic children have lower levels of Iron, Vitamin D, Magnesium, etc – Oct 2017
- Breastfed infants 6 times more likely to deficient in Vitamin D and Iron – Aug 2015
- Anemia 1.9X more likely in white children having lowish vitamin D – Jan 2014
- Review of Micronutrients such as vitamin D for women and childhood – Aug 2013
- Infants who have iron deficiency anemia are 4X more likely to be vitamin D deficient – March 2013
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