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Virus (adeno-36) increases Obesity which then increases risk of another virus (Influenza) - Oct 2013

Effect of adenovirus and influenza virus infection on obesity.

Life Sci. 2013 Oct 11;93(16):531-5. doi: 10.1016/j.lfs.2013.08.016
Hur SJ1, Kim DH, Chun SC, Lee SK.
Department of Bioresources and Food Science, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 143-701, Republic of Korea.

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The purpose of this review is to provide an overview of the effects of adenovirus and influenza virus infections on obesity in various experimental models. We reviewed studies that were conducted within the past 10 years and were related to virus infection and obesity prevalence. Here, we discuss a different causal relationship between adenovirus and influenza infections with obesity.
Adenovirus infection can cause obesity, whereas obesity can be a risk factor for increasing influenza virus infection and increases the risk of morbidity and mortality. The prevalence of obesity due to adenovirus infections may be due to an increase in glucose uptake and reduction in lipolysis caused by an increase in corticosterone secretion. Adenovirus infections may lead to increases in appetite by decreasing norepinephrine and leptin levels and also cause immune dysfunction. The relationship between obesity and influenza virus infection could be summarized by the following features: decreases in memory T-cell functionality and interferon (IFN)-α, IFN-β, and IFN-γ mRNA expression, increases in viral titer and infiltration, and impaired dendritic cell function in obese individuals. Moreover, leptin resistance may play an important role in increasing influenza virus infections in obese individuals.

In conclusion, prevention of adenovirus infections could be a good approach for reducing obesity prevalence, and prevention of obesity could reduce influenza virus infections from the point of view of viral infections and obesity.

Created by admin. Last Modification: Thursday November 7, 2019 19:10:18 GMT-0000 by admin. (Version 3)

Attached files

ID Name Comment Uploaded Size Downloads
12928 Virus obesity virus.jpg admin 07 Nov, 2019 19:03 106.12 Kb 202
12927 Adeno.pdf admin 07 Nov, 2019 19:03 369.03 Kb 147
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