This Vitamin Is Linked To 75% Lower Depression Risk
https://www.spring.org.uk/2018/12/vitamin-lower-depression-risk.php Psyblog
- "Healthy levels of Vitamin D are linked to a 75% lower risk of depression, new research finds."
- "The Irish study followed almost 4,000 older adults for four years."
- "The results showed that those with a vitamin D deficiency had a 75% higher risk of depression."
Intervention of Vitamin D for Depression
- Depression in psychiatric youths reduced 28 percent after just 1 month of vitamin D – RCT Feb 2020
- Yet another study confirms Depression is treated by weekly Vitamin D – RCT Dec 2019
- Depression decreased after vitamin D (50,000 IU weekly to elderly in the case) – RCT Oct 2019
- Vitamin D - no cure for depression (when you use only 1200 IU) – Aug 2019
- Depression reduced in Diabetics with 3 months of 4,000 IU of vitamin D – RCT July 2019
- Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018
- Women had better sexual desire, orgasm and satisfaction after Vitamin D supplementation – Feb 2018
- Vitamin D depression RCT canceled: too many were taking Vitamin D supplements, etc. Feb 2018
- Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017
- Perinatal depression decreased 40 percent with just a few weeks of 2,000 IU of vitamin D – RCT Aug 2016
- Just 1500 IU of Vitamin D significantly helps Prozac – RCT March 2013
- Reduced depression with single 300,000 IU injection of vitamin D – RCT June 2013
- 40,000 IU vitamin D weekly reduced depression in many obese subjects – RCT 2008
- 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013
Meta-analyses of Vitamin D and Depression
- Mental disorders fought by Omega-3 etc. - meta-meta-analysis Oct 2019
- Depression less likely if more Vitamin D (12 percent per 10 ng) – meta-analysis July 2019
- Anxiety severity reduced if more than 2 grams of Omega-3 – meta-analysis Sept 2018
- Less depression in seniors taking enough Omega-3 – meta-analysis July 2018
- Unipolar depression treated by Omega-3, Zinc, and probably Vitamin D – meta-analysis Oct 2017
- Depression is associated with low Magnesium – meta-analysis April 2015
- Clinical Trials of vitamin D can have “biological flaws” – Jan 2015
- Slight depression not reduced by adding vitamin D if already had enough (no surprise) – meta-analysis – Nov 2014
- Anti-depression medication about as good as big increase in vitamin D – meta-analysis of flawless data April 2014
- Depression might be reduced by vitamin D – meta-analysis March 2014
- Low vitamin D and depression - Study and meta-analysis, April 2013
- 2X more likely to be depressed if low vitamin D (cohort studies) - Meta-analysis Jan 2013
Depression category listing has 215 items along with related searches10 most recently added items in Depression category in Vitamin D Life
- Risk of Major Depressive Disorder increased 2.2 X by a poor Vitamin D receptor – Oct 2020
- 2.3 X increase in COVID-19 death if mentally ill (associations: Mental Illness and Low Vitamin D, Low D and COVID-19 death) – Oct 2, 2020
- Depression strongly associated with low Vitamin D – Review Jan 2020
- Vitamin D reduced depression – single 300,000 IU – RCT Aug 2020
- Middle Eastern women living in Sweden 23X higher risk to be anxious if low vitamin D – Feb 2020
- Depression in psychiatric youths reduced 28 percent after just 1 month of vitamin D – RCT Feb 2020
- Depression associated with poor Vitamin D Receptor (in mice) – Dec 2019
- 95 percent of depressed patients in Egypt had low vitamin D – Feb 2020
- Yet another study confirms Depression is treated by weekly Vitamin D – RCT Dec 2019
- Depression substantially reduced by Vitamin D, Omega-3, Magnesium, etc – many studies
Data for Psyblog report was taken from
Vitamin D Deficiency Is Associated With an Increased Likelihood of Incident Depression in Community-Dwelling Older Adults
Journal of Post-Acute and Long-Term Care Medicine DOI: https://doi.org/10.1016/j.jamda.2018.10.006
Robert Briggs, MB, BCh, BAO MB, BCh, BAO Robert Briggs MB, BCh, BAO Robert Briggs, Kevin McCarroll, MD, Aisling O'Halloran, PhD, Martin Healy, PhD, Rose Anne Kenny, MD, Eamon Laird, PhD
.
Objective :To examine the prospective relationship between vitamin D status and incident depression in a large cohort of nondepressed community-dwelling older people.
Design: Longitudinal study examining the relationship between vitamin D levels at baseline (wave 1) and incident depression at 2 and 4 years (waves 2 and 3), embedded within the Irish Longitudinal Study on Aging. Participants with depression at wave 1 were excluded. Logistic regression models reporting odds ratios were used to analyze the longitudinal association of vitamin D categories with incident depression. Analysis was weighted for attrition.
Setting and Participants: Almost 4000 community-dwelling people aged ≥50 years.
Measures: A score ≥9 on the Center for Epidemiologic Studies Depression Scale-8 at wave 2 or 3 was indicative of incident depression. Vitamin D analysis was performed using liquid chromatography-tandem mass spectrometry and deficiency, insufficiency, and sufficiency were defined as <30, 30–50, and >50 nmol/L, respectively.
Results: The incident depression group (400/3965) had a higher likelihood of baseline vitamin D deficiency (proportional estimation 19.4) [95% confidence interval (CI) 15.1–24.7] vs [12.4 (95% CI 11.1–14.0); Z = 3.93; P < .001]. Logistic regression models demonstrated that participants with vitamin D deficiency had a significantly higher likelihood of incident depression (odds ratio 1.75, 95% CI 1.24–2.46; t = 3.21; P = .001). This finding remained robust after controlling for relevant covariates including physical activity, chronic disease burden, cardiovascular disease and antidepressant use.
Conclusions/Implications: This study demonstrates that vitamin D deficiency is associated with a significant increase in the likelihood of developing depression in later life. These findings are important, given the high prevalence of vitamin D deficiency among older people, the fact that supplementation has a low risk of toxicity or side effects, as well as the significant adverse effect depression can have on functional status and longevity in later life.
This Vitamin Is Linked To 75% Lower Depression Risk - Dec 2018 629 visitors, last modified 11 Feb, 2019,
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10 most recently added items in Depression category in Vitamin D Life
- Risk of Major Depressive Disorder increased 2.2 X by a poor Vitamin D receptor – Oct 2020
- 2.3 X increase in COVID-19 death if mentally ill (associations: Mental Illness and Low Vitamin D, Low D and COVID-19 death) – Oct 2, 2020
- Depression strongly associated with low Vitamin D – Review Jan 2020
- Vitamin D reduced depression – single 300,000 IU – RCT Aug 2020
- Middle Eastern women living in Sweden 23X higher risk to be anxious if low vitamin D – Feb 2020
- Depression in psychiatric youths reduced 28 percent after just 1 month of vitamin D – RCT Feb 2020
- Depression associated with poor Vitamin D Receptor (in mice) – Dec 2019
- 95 percent of depressed patients in Egypt had low vitamin D – Feb 2020
- Yet another study confirms Depression is treated by weekly Vitamin D – RCT Dec 2019
- Depression substantially reduced by Vitamin D, Omega-3, Magnesium, etc – many studies
Data for Psyblog report was taken from
Vitamin D Deficiency Is Associated With an Increased Likelihood of Incident Depression in Community-Dwelling Older Adults
Journal of Post-Acute and Long-Term Care Medicine DOI: https://doi.org/10.1016/j.jamda.2018.10.006
Robert Briggs, MB, BCh, BAO MB, BCh, BAO Robert Briggs MB, BCh, BAO Robert Briggs, Kevin McCarroll, MD, Aisling O'Halloran, PhD, Martin Healy, PhD, Rose Anne Kenny, MD, Eamon Laird, PhD
.
Objective :To examine the prospective relationship between vitamin D status and incident depression in a large cohort of nondepressed community-dwelling older people.
Design: Longitudinal study examining the relationship between vitamin D levels at baseline (wave 1) and incident depression at 2 and 4 years (waves 2 and 3), embedded within the Irish Longitudinal Study on Aging. Participants with depression at wave 1 were excluded. Logistic regression models reporting odds ratios were used to analyze the longitudinal association of vitamin D categories with incident depression. Analysis was weighted for attrition.
Setting and Participants: Almost 4000 community-dwelling people aged ≥50 years.
Measures: A score ≥9 on the Center for Epidemiologic Studies Depression Scale-8 at wave 2 or 3 was indicative of incident depression. Vitamin D analysis was performed using liquid chromatography-tandem mass spectrometry and deficiency, insufficiency, and sufficiency were defined as <30, 30–50, and >50 nmol/L, respectively.
Results: The incident depression group (400/3965) had a higher likelihood of baseline vitamin D deficiency (proportional estimation 19.4) [95% confidence interval (CI) 15.1–24.7] vs [12.4 (95% CI 11.1–14.0); Z = 3.93; P < .001]. Logistic regression models demonstrated that participants with vitamin D deficiency had a significantly higher likelihood of incident depression (odds ratio 1.75, 95% CI 1.24–2.46; t = 3.21; P = .001). This finding remained robust after controlling for relevant covariates including physical activity, chronic disease burden, cardiovascular disease and antidepressant use.
Conclusions/Implications: This study demonstrates that vitamin D deficiency is associated with a significant increase in the likelihood of developing depression in later life. These findings are important, given the high prevalence of vitamin D deficiency among older people, the fact that supplementation has a low risk of toxicity or side effects, as well as the significant adverse effect depression can have on functional status and longevity in later life.
| 629 visitors, last modified 11 Feb, 2019, |