Vitamin D and Neurological Diseases: An Endocrine View
Int. J. Mol. Sci. 2017, 18, 2482; doi:10.3390/ijms18112482
Carolina Di Somma , Elisabetta Scarano , Luigi Barrea , Volha V. Zhukouskaya 2,
Silvia Savastano 2, Chiara Mele<1,5, Massimo Scacchi4,6 , Gianluca Aimaretti ,
Annamaria Colao 2 and Paolo Marzullo paolo.marzullo at med.uniupo.it
Types of evidence that Vitamin D helps brain problems - 2014
- Multiple Sclerosis, Alzheimer’s and Parkinson’s need more than 30 ng of Vitamin D – review Nov 2017
- ALS treated by vitamin D
- Overview Parkinsons and Vitamin D
- Overview MS and vitamin D
- Alzheimer’s, Parkenson’s, and Multiple Sclerosis – vitamin D may prevent and treat – Oct 2017
Alzheimers-Cognition - Overview has the following summary
- FACT: Cognitive decline is 19X more likely if low vitamin D
- FACT: Dementia is associated with low vitamin D levels.
- FACT: Alzheimer’s 21 % more likely if low vitamin D
- FACT: Alzheimer's Disease is 4X less likely if less likely if high vitamin D
- FACT: Every single risk factor listed for Alzheimer's Disease is also a risk factor for low vitamin D levels
- FACT: Elderly cognition gets worse as the elderly vitamin D levels get even lower (while in senior homes)
- OBSERVATION: Reports of increased vitamin D levels result in improved cognition
- OBSERVATION: Alzheimer’s patients 3X more likely to have a malfunctioning vitamin D receptor gene – 2012
- OBSERVATION: Alzheimer's Disease has been seen to halt when vitamin D was added.
- OBSERVATION: 39 vitamin D and Alz. or Cognition lntervention trials as of Sept 2018
- OBSERVATION: 2 Meta-analysis in 2012 agreed that Alzheimer's Disease. associated with low vitamin D
- OBSERVATION: 50X increase in Alzheimer's while decrease in vitamin D
- OBSERVATION: Vitamin D reduces Alzheimer’s disease in 11 ways
- OBSERVATION: Alzheimer’s cognition improved by 4,000 IU of vitamin D
- OBSERVATION: Plaque removed in mice by equiv. of 14,000 IU daily
- FACT: Vitamin D is extremely low cost and has very very few side effects
- CONCLUSION: Everyone concerned about cognitive decline or Alzheimer's Disease should take vitamin D
- PREDICTION: By 2024 Omega-3 and high dose Vitamin D will be found to reverse Alzheimer's in humans
- As of 2018 that combination has worked well with Multiple Sclerosis, Sleep, and Cluster Headaches
- All items in category Cognition and vitamin D
290 Dementia
- Dementia risk factor is increased by 1.5 if low vitamin D – meta-analysis Jan 2017
- Dementia less likely with increased levels of Magnesium etc.
- Dementia 19X more likely if low vitamin D – Jan 2012
- Dementia 13X more likely in elderly with low vitamin D – May 2014
- Dementia risk significantly increased if have 4 chronic diseases – all associated with low vitamin D – Sept 2015
- Search Vitamin D Life for dementia anywhere in text 960 items Nov 2017
Endocrine and Genes
- Autocrine, Paracrine and Endocrine - simple chart
- Brain cells can probably activate Vitamin D without liver or kidney (at least in rats) – Sept 2017
Vitamin D blood test misses a lot
Download the PDF from Vitamin D LifeAbstract: Vitamin D system comprises hormone precursors, active metabolites, carriers, enzymes, and receptors involved in genomic and non-genomic effects. In addition to classical bone-related effects, this system has also been shown to activate multiple molecular mediators and elicit many physiological functions. In vitro and in vivo studies have, in fact, increasingly focused on the "non-calcemic" actions of vitamin D, which are associated with the maintenance of glucose homeostasis, cardiovascular morbidity, autoimmunity, inflammation, and cancer. In parallel, growing evidence has recognized that a multimodal association links vitamin D system to brain development, functions and diseases. With vitamin D deficiency reaching epidemic proportions worldwide, there is now concern that optimal levels of vitamin D in the bloodstream are also necessary to preserve the neurological development and protect the adult brain. The aim of this review is to highlight the relationship between vitamin D and neurological diseases.
Vitamin D and Multiple Sclerosis, Alzheimer's, Parkinson's ,Dementia, and ALS - review Nov 2017(Cached) Printer Friendly PDF this page! Follow this page for updates1822 visitors, last modified 07 Dec, 2017, This page is in the following categories (# of items in each category)Multiple Sclerosis356 Parkinson 82 Top news 814 Cognitive 290 Attached files
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