Some diseases block vitamin D by changing gene activation,
by one or more of the following
- Block conversion of light into vitamin D in the skin
- Block oral absorption in the gut
- Block semi-activation in the liver
- Block free semi-activaed vitamin D from getting to the kidneys
- Block full activation in the kidneys
- Destroy the vitamin D before it gets to the cells
- Block semi and fully activation in the cells
- Block activated Vitamin D from entering cell mitochondria
Some diseases block vitamin D (without changing genes)
- The disease just uses/consumes the vitamin D
- The disease upsets the gut, which reduces bio-availability of oral form
- unless a gut-friendly form is used
References