Rheumatoid Arthritis pain reduced by monthly 100,000 IU of Vitamin D – Oct 2018

An exploratory study on the role of vitamin D supplementation in improving pain and disease activity in rheumatoid arthritis.

Mod Rheumatol. 2018 Oct 4:1-8. doi: 10.1080/14397595.2018.1532622.
Adami G1, Rossini M1, Bogliolo L2, Cantatore FP3, Varenna M4, Malavolta N5, Del Puente A6, Muratore M7, Orsolini G1, Gatti D1, Viapiana O1; Study Group on Osteoporosis and Metabolic Skeletal Diseases of the Italian Society of Rheumatology (SIR).

PDF is available free at Sci-Hub   10.1080/14397595.2018.1532622

RA pain before and after 3 months
effectively after 2 doses of 100,000 IU
Visual Pain scale of 0-10

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101 RA items     See also Overview Rheumatoid Arthritis   Autoimmune  Inflammation   Pain - Chronic

    Highlights of RA studies in Vitamin D Life
RA worse if low Vitamin D

• Rheumatoid arthritis pain was 5.8 X more likely if low vitamin D – Aug 2017
• Adaptive and innate immune system, vitamin D genes, and Rheumatoid Arthritis – June 2019
• Every patient with rheumatoid arthritis had low vitamin D, severity was proportional to degree of deficiency – June 2014
• Active Rheumatologic disease was 5X more likely with low vitamin D – June 2013
• Rheumatoid Arthritis strongly associated with low vitamin D – meta-analysis April 2016
• Rheumatoid Arthritis associated with lower vitamin D and higher latitude – meta-analysis Jan 2016

RA and Vitamin D Receptor

• Arthritis runs in Pakistani families (Vitamin D Receptor) – March 2019
• Resveratrol Role in Autoimmune Disease-A Mini-Review. – Dec 2016
• Rheumatoid arthritis is 40 percent more likely if vitamin D Receptor problem – 2 meta-analyses 2015

RA Treated by Vitamin D

• Rheumatoid Arthritis pain reduced by monthly 100,000 IU of Vitamin D – Oct 2018
• Rheumatoid arthritis reduced by 440,000 IU of Vitamin D over 4 months – Oct 2015
• Connective tissue disorders (Lupus, RA, etc) treated by vitamin D – May 2016
• 43 percent of Rheumatoid Arthritis patients have Vitamin D prescriptions (15 countries) – June 2017
• Big increase in vitamin D supplementation in just 2 years after Swiss rheumatology report – Dec 2013
• High dose vitamin reduced pain of fibromyalgia, osteoarthritis, and rheumatoid arthritis - July 2015
  • Note: Vitamin D receptor problems (such as RA) are best treated by infrequent large doses of Vitamin D