Loading...
 
Toggle Health Problems and D

Folate and Vitamin B6 decrease mortality – May 2022


Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort

Nutrients 2022, 14(11), 2253; https://doi.org/10.3390/nu14112253
by Yacong Bo 1,Huadong Xu 2ORCID,Huanhuan Zhang 1,Junxi Zhang 3,Zhongxiao Wan 1ORCID,Xin Zhao 4,* andZengli Yu 1,3,*
1The Fifth Affiliated Hospital, School of Public Health, Zhengzhou University, Zhengzhou 450000, China
2 School of Public Health, Hangzhou Medical College, Hangzhou 310013, China
3 NHC Key Laboratory of Birth Defects Prevention, Henan Key Laboratory of Population Defects Prevention, Zhengzhou 450000, China
4 The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China

Image
Image
The evidence regarding the intake of dietary folate, vitamin B6, and vitamin B12 in relation to mortality in the general population is limited. This study aimed to examine the relationship between dietary intakes of folate, vitamin B6, and vitamin B12 in relation to all-cause and cause-specific mortality in a large U.S. cohort. This study included a total of 55,569 adults from the Third National Health and Nutrition Examination Survey (NHANES III) and NHANES 1999–2014. Vital data were determined by linking with the National Death Index records through 31 December 2015. Cox proportional hazards models were used to investigate the relationships of all-cause and cause-specific mortality with dietary folate, vitamin B6, and vitamin B12 intake. Dietary intakes of folate and vitamin B6 were inversely associated with mortality from all-cause, cardiovascular disease, and cancer for men and with mortality from all-cause and cardiovascular disease for women. In men, the multivariable hazard ratios (95% confidence intervals) for the highest versus lowest quintiles of folate and vitamin B6 were 0.77 (0.71–0.85) and 0.79 (0.71–0.86) for all-cause mortality, 0.59 (0.48–0.72) and 0.69 (0.56–0.85) for CVD mortality, and 0.68 (0.56–0.84) and 0.73 (0.60–0.90) for cancer mortality, respectively. Among women, the multivariable hazard ratios (95% confidence intervals) for the highest versus lowest quintiles of folate and vitamin B6 were 0.86 (0.78–0.95) and 0.88 (0.80–0.97) for all-cause mortality and 0.53 (0.41–0.69) and 0.56 (0.44–0.73) for CVD mortality, respectively. No significant associations between dietary vitamin B12 and all-cause and cause-specific mortality were observed. In conclusion, higher dietary intakes of folate and vitamin B6 were significantly associated with lower all-cause and cardiovascular mortality. Our findings suggest that increasing the intake of folate and vitamin B6 may lower the mortality risk among U.S. adults.
 Download the PDF from Vitamin D Life


Vitamin D Life pages with FOLATE in title (15 as of May 2022)

This list is automatically updated

Items found: 16
Title Modified
High dose vitamin D fights Folate gene changes by COVID, autoimmune, CVD, ALZ – Oct 2022 06 Oct, 2022
Folate and Vitamin B6 decrease mortality – May 2022 27 May, 2022
Important Role of Micronutrients during COVID-19 (Zinc, Vitamin D, C, Folate) – May 5, 2021 06 May, 2021
Higher vitamin D is associated with higher Folate or higher Vitamin B-12 – June 2020 13 Jul, 2020
Sweat types, folate, binding protein, lighter skin in females and Vitamin D – Jan 2020 19 Jan, 2020
Glyphosate (Roundup) kills both weeds and the microbes in your gut that produce Folate – July 2019 11 Jul, 2019
Dr. Coimbra interview covering Vitamin D, Magnesium, Folate, Vaccines - Oct 2018 24 Nov, 2018
Neural tube defects more likely due to low vitamin D than low Folate – April 2017 15 Sep, 2018
Off topic – Folate can be produced by micro-organisms, can avoid synthetic Folic Acid – Aug 2018 02 Aug, 2018
First-Episode Psychosis associated with low Vitamin D, Vitamin C and Folate – meta-analysis Nov 2017 22 Dec, 2017
Increased cows milk allergy if Folic acid or Folate added to vitamin D during pregnancy – June 2016 05 Apr, 2017
Autism 17 times more likely with excessive Folate and B-12 (now added to bread) – May 2016 09 Jun, 2016
Autism 17X more likely when have excessive levels of Folate and B-12 – May 2016 12 May, 2016
Vitamin D and Folate fortification of foods - April 2012 25 Apr, 2015
Neural tube defects of pregnant mice reduced by Vitamin D (perhaps less Folate needed) – April 2015 25 Apr, 2015
Hypothesis – Increasing Folate or vitamin D decreases probability of skin cancer – July 2012 02 Aug, 2012



Created by admin. Last Modification: Friday May 27, 2022 17:30:48 GMT-0000 by admin. (Version 3)

Attached files

ID Name Comment Uploaded Size Downloads
17675 Mortality B6.jpg admin 27 May, 2022 17:28 24.91 Kb 46
17674 Mortality Folate.jpg admin 27 May, 2022 17:28 40.29 Kb 55
17673 Mortality B vitamins.pdf PDF 2022 admin 27 May, 2022 17:27 583.59 Kb 39
See any problem with this page? Report it (WORKS NOV 2021)