Research prioritization of interventions for the primary prevention of preterm birth: An international survey.
Eur J Obstet Gynecol Reprod Biol. 2019 Jan 25. pii: S0301-2115(19)30048-X. doi: 10.1016/j.ejogrb.2019.01.021.
Allotey J1, Matei A2, Husain S3, Newton S4, Dodds J5, Armson AB2, Khan KS5, Vogel JP6.
- Preterm births are VERY costly – Feb 2017
- Preterm birth rate reduced by vitamin D – 78 percent if non-white, 39 percent if white – July 2017
Omega-3
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- Preterm births strongly related to Vitamin D, Vitamin D Receptor, Iodine, Omega-3, etc
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Vitamin D Receptor
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- Preterm birth far more likely if previous miscarriage and poor Vitamin D receptor – Aug 2017
- Vitamin D Receptor is associated with preeclampsia, gestational diabetes and preterm birth – Nov 2017
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Just Vitamin D5 (1.0) Affordability to women The intervention will be affordable to women 5 (1.0) Affordability to HCP The intervention will be affordable to health careproviders 5 (1.0) Acceptability to women The intervention will be acceptable to women 5 (0) Acceptability to HCP The intervention will be acceptable to health careproviders 5 (1.0) Implementation The intervention can be implemented 5 (1.0) Sustainability The intervention can be sustained in the long-term 4 (2.0) Equity The intervention will reach the most vulnerablegroups and reduce health inequity 4 (2.0) Effectiveness of an RCT An RCT on this intervention is likely to demonstrate desirable or beneficial effects 5 (1.0) Feasibility of an RCT An RCT on this intervention would be feasible 5 (1.0 Summary Score Vitamin D, Omega-3, etc
OBJECTIVE:
To identify research priorities of interventions for the primary prevention of preterm birth (PTB), by conducting an international stakeholder survey.STUDY DESIGN:
A prospective cross-sectional online survey was conducted in November 2016. Fifteen interventions to prevent spontaneous PTB were identified and ranked by stakeholders (n = 159) in the field of maternal and perinatal health research, using nine equally weighted criteria. Medians and interquartile ranges (IQRs) were calculated and the interventions ranked accordingly.RESULTS:
Respondents to the survey were from 46 different countries, mostly from low and middle-income countries (62%, 99/159) and were mainly clinicians (80%, 127/159). Of the fifteen interventions ranked, the following five were identified as research priorities in the primary prevention of PTB: dietary counselling and nutritional education, risk scoring, vitamin D supplementation, exercise and antioxidant supplementation.CONCLUSION:
We have identified research priorities of interventions to prevent spontaneous PTB through a global stakeholder survey. The interventions prioritized in this exercise can be used by researchers, grant funding bodies and research-policy decision makers to inform calls on future clinical trials or individual patient data meta-analyses on the primary prevention of PTB.Preterm birth might be prevented by Vitamin D, Omega-3, etc. (International survey) – Jan 2019Printer Friendly PDF this page! Follow this page for updates940 visitors, last modified 04 Feb, 2019, This page is in the following categories (# of items in each category)Pregnancy750 Attached files
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