Vitamin D supplementation guidelines (adults – 50,000 IU per week) – Feb 2017

The Journal of steroid biochemistry and molecular biology · Feb 2017, DOI: 10.1016/j.jsbmb.2017.01.021
Pawel Pludowski, Michael F. Holick, William B., Grant, Jerzy Konstantynowicz, Mario R. Mascarenhas, Afrozul Haq, Vladyslav Povoroznyuk, Nataliya Balatska, Ana Paula Barbosa, Tatiana Karonova, Ema Rudenka, Waldemar, Misiorowski, Irina Zakharova, Alena Rudenka, Jacek Łukaszkiewicz, Ewa Marcinowska-Suchowierska, Natalia Łaszcz, Pawel Abramowicz, Harjit P. Bhattoa, Sunil J. Wimalawansa

Group	Age	IU/day	mcg/day
Neonates	< 1 month	1,000 IU	25 mcg
Infants	1 - 12 months	2000-3000 IU	50-75 mcg/
Children and adolescents	1 - 18 years	3000-5000 IU	75–125 mcg
Adults and the elderly	18+ years	7000–10,000 IU 50,000 IU/week	175–250 mcg

 Download the SciHub PDF (accepted manuscript) via Vitamin D Life

Clips from PDF

• “It is generally accepted that a serum 25(OH)D concentration of up to 100 ng/mL is safe for children and adults, with the exception of those who have a hypersensitivity to vitamin D.”
• ““The Endocrine Society guidelines concluded that vitamin D toxicity is not only extremely rare, but 25(OH)D concentration of at least 150 ng/mL is required before there would be evidence of vitamin D toxicity.”
• “25(OH)D concentrations of 30-50 ng/mL (75-125 nmol/L) are beneficial for overall health

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This study does not address

1. Increased vitamin D needs for Overweight/Obese, Pregnant, Premies, Sick, etc.
2. People with genes (5 kinds) which restrict blood vitamin D from getting to the cells
3. Cofactor adjustments when Vitamin D level is > 30 ng for > 1 year
4. Loading dose - to quickly restore vitamin D levels
5. Other types of vitamin D - for those with poor guts, vegitarians, . .
6. Other forms of vitamin D: topical, injection, inhaled, Calcitriol, etc.
7. Hypersensitivity is often due to low levels of Magnesium
8. When to take the vitamin D (with largest meal of the day)

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Getting Vitamin D into your body has the following chart

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See also Vitamin D Life

• 1000 IU should be the new vitamin D RDA (if you think 20 ng is enough) - May 2017
• Vitamin D math mistake had been made, adults need at least 8000 IU – July 2017
• 50,000 IU of vitamin D every two weeks – Jordan conclusion - RCT July 2017
• Vitamin D needs in 2004:1000 IU, 10 years later same author says 3,500 IU Dr. Holick
• Is 50 ng of vitamin D too high, just right, or not enough
• Vitamin D Recommendations around the world - IU and ng has the following 2012 chart