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How active vitamin D stops various cancers – abstract Oct 2010

The potential role of vitamin D in the progression of benign and malignant melanocytic neoplasms

Authors: Pinczewski, Joel; Slominski, Andrzej1
Experimental Dermatology, Volume 19, Number 10, October 2010 , pp. 860-864(5)

Hormonally active vitamin D3, 1,25-(OH)2D3, is believed to have a role in the prevention of cancer formation and in limiting the aggressiveness of cancers that do arise. Therefore, much interest is presently being focused on 1,25-(OH)2D3 and its analogues as potential treatments for various cancers including melanoma. This article discusses the evidence in favour of a role for 1,25-(OH)2D3 in protection against the progression of melanocytic lesions and also summarizes the mechanisms by which 1,25-(OH)2D3 may act to protect against melanoma development and progression. DOI: 10.1111/j.1600-0625.2010.01169.x

How active vitamin D stops various cancers – abstract Oct 2010

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