Use of vitamin D and infection in patients with chronic kidney disease.
Rev Bras Enferm. 2018;71(suppl 6):2792-2799. doi: 10.1590/0034-7167-2018-0640.
[Article in English, Portuguese]
Silva ECD1, Taminato M1, Fonseca CDD1, Moraes GM1, Longo MCB1, Grothe CE1, Belasco AGS1, Barbosa DA1. ~ha~ dulce.barbosa at unifesp.br
Study amazingly does not state the size of loading nor maintenance doses
Unsure the time period for infection statistics – 0-6 months, 3-6 months? 5-6 months?
Did all chronic kidney patients get maintenance dose?
Kidney category starts with
Kidney category listing hassee also Overview Kidney and vitamin D
Search Vitamin D Life for dialysis OR haemodialysis 878 items not in PDF as of Aug 2020
Search Vitamin D Life for kidney transplant 798 items as of June 2019
"Chronic Kidney Disease" OR CKD 874 items as of Jan 2018
Kidney Intervention trials using Vitamin D:
- Chronic Kidney Disease (stage 3) slowed by 30 ng of Vitamin D and Calcitriol – Dec 2019
- Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT Jan 2019
- Hemodialysis patients (CKD) helped by weekly 50,000 IU of vitamin D – Jan 2017
- Kidney disease helped by active or high dose Vitamin D - Feb 2014
- Peritoneal Dialysis nicely treated by active vitamin D – July 2013
- 7100 IU (50000 weekly) restored vitamin D levels for those with Chronic Kidney Disease – July 2012
- Chronic Kidney Disease reduced with 3600 IU vitamin D (50000 twice a month)– RCT Aug 2012
- Overview Kidney and vitamin D
Overview Kidney and vitamin D contains the following summary
- FACT: Kidney is the primary way to activate vitamin D
- FACT: When the Kidney has problems, there is less active vitamin D (Calcitriol) for the body
- FACT: When the Kidney has problems, there is increased death due to many factors - many of which are associated with lack of Calcitriol
- FACT: There are many on-going intervention clinical trials trying to determine how much of what kind of vitamin D is needed to treat the problem
- FACT: One Randomized Controlled Trial has proven that Vitamin D treats CKD
- FACT: Taking extra Vitamin D, in various forms, does not cause health problems - even if poor kidney
- Suggestion: Increase vitamin D getting into body now - and increase co-factors so that the vitamin D can be better used
Sun, UV lamp, Vitamin D supplement - probably > 5,000 IU,
Calcitriol - which bypasses the need for the kidney to activate vitamin D
Problems with Calcitriol however: typically only lasts for a few hours, also, possible complications
Update: Pre-cursor of active vitamin D made from plants is better than calcitriol – Sept 2012 - Category Kidney and Vitamin D contains
193 items Download the PDF from Vitamin D Life
Supplement Infection Vitamin D 16 % No D 32 % Blood level Loading Dose Maint. Dose <20 ng/mL 3 months 3 months? 20–19 ng/mL 3 month; 3 months? >30 ng/mL no maintenance dose
3 month or 6 month?
OBJECTIVE:
To evaluate the effectiveness of vitamin D supplementation as protection factor against infection of patients with chronic kidney disease on conservative treatment.METHOD:
Retrospective cohort study carried out between 2013 and 2016 in the Conservative Treatment Outpatient Clinics (Ambulatório de Tratamento Conservador) of the Hypertension and Kidney Hospital (Hospital do Rim e Hipertensão) of the Universidade Federal de São Paulo. Data on sociodemographic factors, comorbidity, infection episodes and use or nonuse of vitamin D supplementation for at least 6 months were collected from medical records. The primary outcomes considered in both groups were: presence or absence of infection anywhere on the body (bloodstream, urinary, respiratory and surgical sites).RESULTS:
A total of 263 patients were included and those who received (n=43) vitamin D had 59% less chance of developing infections (OR=0.41; 95%CI; 0.15-0.99), when compared to those who did not receive.CONCLUSION: Vitamin D supplementation was a protective factor against infections of all causes.
Half as much chronic kidney disease infection if supplement with Vitamin D – 2018Printer Friendly PDF this page! Follow this page for updates779 visitors, last modified 15 Mar, 2019,