Eighth Annual AACR International Conference on Frontiers in Cancer Prevention Research

1. Abenaa M. Brewster1,
2. Sherri L. Patterson1,
3. Michele R. Forman1,
4. Chanita Hughes-Halbert2,
5. Paul J. Limburg3,
6. Frank G. Ondrey4,
7. Electra D. Paskett5,
8. David W. Wetter1 and
9. Ernest T. Hawk1
1. Authors' Affiliations:1The University of Texas M.D. Anderson Cancer Center, Houston, Texas; 2University of Pennsylvania, Philadelphia, Pennsylvania; 3Mayo Clinic, Rochester, Minnesota; 4University of Minnesota, Minneapolis, Minnesota; and 5The Ohio State University, Columbus, Ohio
1. Corresponding Authors:
Abenaa M. Brewster, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1360, Houston, TX 77030. Phone: 713-745-4928; Fax: 713-745-4230; E-mail: abrewster at mdanderson.org or spatterson at mdanderson.org.
The Eighth Annual Frontiers in Cancer Prevention Research meeting was held in Houston, Texas, in November 2009. This report highlights significant presentations that advance the fields of chemoprevention, clinical trial recruitment and retention, cancer screening including optical imaging, energy balance, and nutritional epidemiology, and health communications and decision making. In findings from the randomized Reduction by Dutasteride of Prostate Cancer Events trial, dutasteride reduced the risk of biopsy-detectable prostate cancer in high-risk men by 23% compared with placebo.

Important clues about the dosing and window of susceptibility for supplementation with choline, vitamin D, and folate were revealed from epigenetic research that has implications for future nutritional epidemiology research. Noninvasive optical imaging techniques using endoscopic ultrasound and autofluorescence for the early detection of cancers in the lung, pancreas, and oral cavity are being studied. The report also addresses the challenges of promoting cancer prevention. Understanding how individuals process risk information and make sustained behavior changes and the effect of socioeconomic status on health disparities were identified as critical areas of research. This multidisciplinary research meeting of basic, clinical, and behavioral scientists and epidemiologists continues to play a major role in identifying the research priority areas of cancer prevention, elucidating new mechanisms of carcinogenesis for targeted chemoprevention therapies and delivering a comprehensive strategy for engaging individuals in the unifying goal to reduce cancer incidence. Cancer Prev Res; 3(8); 1044–8. ©2010 AACR.