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Strong proof that TAKING vitamin D reduces diseases - currently 20
| Health Problem | Reduction | Notes | # |
| Hypertension | 149=>142 | RCT, mm Hg, 2400 IU | 1 |
| Cardiovascular | 32 % | Death after heart failure, 1000 IU | 2 |
| Diabetes T1 | 85 % | 12000 kids, 2000 IU | 3 |
| Diabetes T2 | 62 % | RCT, CRP reduction, 4000 IU | 4 |
| Back Pain | 95 % | 5000/10000 IU | 5 |
| Influenza | 90 % | RCT, 2000 IU | 6 |
| Falls | 19 % | RCT, 1000 IU | 7 |
| Hip Fractures | 30 % | Meta-analysis 800 IU | 8 |
| Rickets | 98 % | Turkey, 400 IU | 9 |
| Raynaud's pain | 40 % | RCT, visual scale, 20000 IU avg | 10 |
| Menstrual Pain | 76 % | RCT, visual scale, 7000 IU avg | 11 |
| Pregnancy risks | 50 % | RCT, 4000 IU | 12 |
| C-section, unplanned | 50 % | RCT was underpowered 4000 IU | 13 |
| Low birth weight | 60 % | Meta-analysis 1000 IU of D2 | 14 |
| TB | 60 % | RCT 800 IU | 15 |
| Breast Cancer | 60 % | RCT 1100 IU | 16 |
| RA pain reduction | 40 % | RCT 500 IU, added to DMARD | 17 |
| Cystic Fibrosis | 75 % | RCT pilot 4X fewer deaths 250,000 IU | 18 |
| Chronic Kidney | 90=>70 PTH | RCT 3500 IU | 19 |
| Respiratory Tract Infection | 50 % | RCT 300 IU, children | 20 |
101 NEW Vitamin D INVERVENTION trials were registered during the first 7 months of 2012
It is getting to be very popular to take a group of people and give vitamin D to half and see what happens.
The results of these trials provides data for the above table.
Anticipate having proof that vitamin D helps 30+ diseases by Spring 2013
Vitamin D levels in healthy populations around the globe - Aug 2012 with a link to similar publication in Aug 2011
Infants and Children
Unsupplemented infants were 19X more likely to be vitamin D deficient - May 2012
Omega-3
US supplements survey - 34 % take omega-3, 30 % take vitamin D - Aug 2012
Omega 3 increased by 60% the ACTIVE vitamin D in the blood - Aug 2012
Looking very important to take BOTH Omega-3 and Vitamin D
Note: standard blood test does NOT measure ACTIVE vitamin D
Bone and muscle loss associated with have low vitamin D
Loss of muscle strength -sarcopenia - one of the suspects is vitamin D - Aug 2012
NASA thinks spacestation personnel only need 800 IU of vitamin D - Sept 2012
It took NASA 40+ years to realize that bone loss in space might be due to lack of vitamin D
NASA has not yet considered that the muscle loss in space might also be due to lack of vitamin D: see the sarcopenia item above as well
5X increase in hip fracture rates in 65 years similar to the decline in vitamin D
Breathing
Just 300 IU daily of vitamin D reduced respiratory infections by 50% - RCT Aug 2012
Many studies have shown breathing associated with higher levels of vitamin D
In this study 100 % of Acute Respiratory Failure patients had low vitamin D
When
How often should I take 50,000 IU of vitamin D Every 30, 15, 10, 7, 5, or 3 days?
50,000 IU vitamin D3 is by far the lowest cost vitamin D size, and is easy to recall when to take it.
50,000 IU vitamin D3 is the only size available by prescription (in the US, at least)
Just mark your calendar for vitamin D days - example on monthly calendar, every two weeks
Other vitamin D
Would you be opposed to my getting more vitamin D? A way of wording your question to your doctor
This phrasing minimizes the doctor's need to answer with minimum liability exposure
If you are obese, use sunscreen, or don't drink milk you may be vitamin D deficient - March 2012
Other studies find that use of sunscreen INCREASES vitamin D - perhaps because the sunscreen is not put on very well, or replenished.
NYC Vitamin D Conference Sept 21, 2012
PDF with audio will be available after the conference for those who cannot attend
2X higher death rate if have 13 ng instead of 20 ng of vitamin D Not just the elderly!!
Some people on Chinese beaches appear to really want whiter and/or wrinkle-free faces
Multiple Sclerosis Overview was recently revised
Ann Romney (yes, his wife) had been diagnosed with MS, but is in remission after being outdoors a lot
Neurology J. had 4 items on Multiple Sclerosis and Vitamin D - review by MS Soc Aug 2012
3X more vitamin D from the sun if take MS drug Interferon-?
By the way: in July 2012 JAMA announced that Interferon-? does not reduce MS outcomes
Half-life of vitamin D varies longest = UVB, middle = D3, shortest = D2
The half life also varies with the amount of vitamin D in your blood.
Other Diseases
>30 ng of vitamin D probably needed for long-latency diseases - Aug 2012
A study way back in 2006 showed decrease in diseases with increasing Vitamin D levels
Hypertension 2X more likely when vitamin D levels lower than 14 ng - meta-analysis May 2012
Increase vitamin D lowers hypertension very quickly
Statins associated with 14X increase in Polymyalgia Rheumatica (a new disease) - Aug 2012
7100 IU (50,000 weekly) restored vitamin D levels for those with Chronic Kidney Disease - July 2012
Probability of Type I diabetes reduced 29 % with vitamin D - systematic review July 2012
Major depression associated with low vitamin D and low bone density - July 2012
Death due to cystic fibrosis reduced about 4X due to 250,000 IU of vitamin D - RCT June 2012
CDC published the latest chart on increase in Diabetes 1980==> 2010
Hospitals
Several papers on Vitamin D for critically ill children in Journal of Pediatrics - Aug 2012
Plasma exchange cut vitamin D levels in half - June 2012
This is a big surprise. 300,000 people get plasma exchanges each year
(plasma exchanges remove the vitamin D carrier from the blood)
Intravenous Feeding in hospitals still only provides 200 IU of Vitamin D per day
Low replenishment just when people need the healing features of vitamin D the most.
And, while being in the hospital a person is very unlikely to get outdoors in the sunshine
UVB (vitamin D) from lamps and the sun
UVB lamp produced 8X as much vitamin D as same intensity from the sun - July 2012
Perhaps the 8X more vitamin D was due to the greatly reduced level of UVA
Sperti UVB lamp is the only one which the FDA has approved for generation of Vitamin D
At $425, it is about 1/5 the cost of a tanning bed, but 20X the cost of vitamin D supplements for 5 years
Note: Sperti has about 100X less UVA than the sun or tanning beds - so it MAY produce a lot of vitamin D per minute of exposure
New Zealand doctors are starting to prescribe more sunshine - Aug 2012
Following so many decades if avoiding the sun with: slip, slop, slap in NZ and Australia
The following figure shows
- You get only 10% of UVB you get while standing with lots of clothes on vs lying down in swim suit
- There is no UV Winter unless you are very very far from the equator
- You continue to get some UVB/vitamin D after your shadow is longer than you are.
Vitamin D from the sun thru a special window or it could be used as a heat shield near the equator
You can filter out all but UVB by putting very thin silver foil on a special plexiglass window
Cartoon: prescription for sunshine
How much vitamin D?
Really hard to specify how many IU of vitamin D an individual should have
3X variation between people in response to dose of vitamin D – meta-analysis June 2012
Chart has 3 different recommendations for Vitamin D
Including the latest from Europe for the maximum levels (4,000 IU for ages >10)
2900 IU of vitamin D (20,000 weekly) kept levels above 20 ng during the winter – Aug 2012
Age
Your intestines absorb less vitamin D less as you age
So many ideas in such a simple chart
Vitamin D levels decrease with age
Hard to get 1,000 IU of vitamin D with skin types II and III
It costs a lot of money to go on a vacation to a sunny climate to get 1,000+ IU per day
Chart from Germany also shows that
Low vitamin D levels (right hand column) occur more frequently as you age (bottom of the column)
Overview of Parkinson's Disease updated
Breast Cancer
CLICK HERE for all Breast Cancer Web pages
Breast Cancer rate increased 3X in 35 years (while vitamin D levels fell dramatically)
Compelling evidence - Breast Cancer and vitamin D - Dissertation June 2012
Recent new categories of information in Vitamin D Life
Europe Canada Aust-NZ
Falls and Fractures Infant-Child Sleep High Risk groups Fortification
Intervention Hypertension Cognitive Decline Stroke
CLICK HERE for All categories in Vitamin D Life
Major updates to many Overviews in Vitamin D Life including:
Vitamin K2 Pregnancy Parkinson's Disease Multiple Sclerosis
Vitamin D News - July 2012
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