A paltry 400 IU Vitamin D recommended during pregnancy - NICE UK Dec 2018

NICE (National Institute of Health Care Excellence) Summary

NICE 2018 previous guidelines = 2008

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• Just 400 IU of daily Vitamin D reduced miscarriage (recurrent) by 3.5 times – RCT July 2016
  • 400 IU is thus proven to provide some benefit
• UK proposes that 10 ng level and 400 IU is enough Vitamin D for everybody (no and no)- July 2015
• Vitamin D pill meets new UK guidelines (400 IU) - Dec 2016
• Intervention - Vitamin D Of the 330 trials, only 4 found success with 400 IU vitamin D (Dec 2016)
  • Note: Only Korea recommends a smaller dose size = 200 IU
• 4,000 IU of Vitamin D is OK - 19 organizations agree - 2018

Benefits of >4,000 IU during pregnancy

Healthy pregnancies need lots of vitamin D has the following summary

Problem	Reduces	Evidence
0. Chance of not conceiving	3.4 times	Observe
1. Miscarriage	2.5 times	Observe
2. Pre-eclampsia	3.6 times	RCT
3. Gestational Diabetes	3 times	RCT
4. Good 2nd trimester sleep quality	3.5 times	Observe
5. Premature birth	2 times	RCT
6. C-section - unplanned	1.6 times	Observe
Stillbirth - OMEGA-3	4 times	RCT - Omega-3
7. Depression AFTER pregnancy	1.4 times	RCT
8. Small for Gestational Age	1.6 times	meta-analysis
9. Infant height, weight, head size      within normal limits		RCT
10. Childhood Wheezing	1.3 times	RCT
11. Additional child is Autistic	4 times	Intervention
12.Young adult Multiple Sclerosis	1.9 times	Observe
13. Preeclampsia in young adult	3.5 times	RCT
14. Good motor skills @ age 3	1.4 times	Observe
15. Childhood Mite allergy	5 times	RCT
16. Childhood Respiratory Tract visits	2.5 times	RCT

RCT = Randomized Controlled Trial

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Pregnancy category starts with

750 items in Pregnancy category

 - see also

• Overview Pregnancy and vitamin D
• Number of articles in both categories of Pregnancy and:
  Dark Skin 25;   Depression 17;   Diabetes 39;   Obesity 12;  Hypertension 35;   Breathing 29;  Omega-3 30;  Vitamin D Receptor 18
• All items in category Infant/Child 606 items
• breastfed 887 items as of Jan 2018
• Preeclampsia 825 items as of Jan 2018
• Pre-term 4710 items as of Dec 2018
• "polycystic ovary syndrome" OR PCOS 303 items as of Jan 2018
• Gestational Diabetes
• c-section OR "caesarean section" (various spellings) 937 items as of Aug 2020
• postpartum depression 208 items as of Aug 2018
• Search VitaminDiiki for MISCARRIAGE OR "Spontaneous abortion" 794 as of Feb 2020
• Search Vitamin D Life for "Assisted reproduction" 33 items as of Feb 2017
• Fertility and Sperm category listing has 109 items along with related searches
• (Stunting OR “low birth weight” OR LBW) 1180 items as of June 2020
• Healthy pregnancies need lots of vitamin D
• Ensure a healthy pregnancy and baby - take Vitamin D before conception