Title of this page (without 800 IU) is from Reuters article
More precise title for the article would have been:
"Once again it has been proven that 800 IU of vitamin D is not enough to prevent heart attacks or reduce cancer"
Need at least 2,000 IU of vitamin D to start to PREVENT Cancer or heart attacks
Similar article: 800 IU Vitamin D does not help heart – meta-analysis Aug 2011
The following chart shows how much vitamin D has to be in blood to prevent many medical problems
It is virtually impossible for 800 IU to result in a 40 ng vitamin D level in the blood
CLICK HERE for larger image and more charts of disease incidence
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The article
Long-Term Follow-Up for Mortality and Cancer in a Randomized Placebo-Controlled Trial of Vitamin D3 and/or Calcium (RECORD Trial).
J Clin Endocrinol Metab. 2011 Nov 23.
Avenell A, Maclennan GS, Jenkinson DJ, McPherson GC, McDonald AM, Pant PR, Grant AM, Campbell MK, Anderson FH, Cooper C, Francis RM, Gillespie WJ, Robinson CM, Torgerson DJ, Wallace WA; the RECORD Trial Group.
Health Services Research Unit (A.A., G.S.M., D.J.J., G.C.M., A.M.M., P.R.P., A.M.G., M.K.C.), University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom; Geriatric Medicine (F.H.A.), Developmental Origins of Health and Disease, Research Division, and Medical Research Council Lifecourse Epidemiology Unit (C.C.), University of Southampton, Southampton SO16 6YD, and Institute of Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, United Kingdom; Institute for Ageing and Health (R.M.F.), Newcastle University, Newcastle upon Tyne NE4 5PL, United Kingdom; Hull York Medical School (W.J.G.), University of Hull, Hull HU6 7RX, United Kingdom; Royal Infirmary of Edinburgh (C.M.R.), Edinburgh EH3 9HB, United Kingdom; York Trials Unit (D.J.T.), University of York, York YO10 5DD, United Kingdom; and Medical and Surgical Sciences (W.A.W.), University of Nottingham, Nottingham NG7 2UH, United Kingdom.
Context:Vitamin D or calcium supplementation may have effects on vascular disease and cancer.Objective:Our objective was to investigate whether vitamin D or calcium supplementation affects mortality, vascular disease, and cancer in older people.Design and Setting:The study included long-term follow-up of participants in a two by two factorial, randomized controlled trial from 21 orthopedic centers in the United Kingdom.Participants:Participants were 5292 people (85% women) aged at least 70 yr with previous low-trauma fracture.
Interventions:Participants were randomly allocated to daily vitamin D(3) (800 IU), calcium (1000 mg), both, or placebo for 24-62 months, with a follow-up of 3 yr after intervention. Main Outcome Measures:All-cause mortality, vascular disease mortality, cancer mortality, and cancer incidence were evaluated.Results:In intention-to-treat analyses, mortality [hazard ratio (HR) = 0.93; 95% confidence interval (CI) = 0.85-1.02], vascular disease mortality (HR = 0.91; 95% CI = 0.79-1.05), cancer mortality (HR = 0.85; 95% CI = 0.68-1.06), and cancer incidence (HR = 1.07; 95% CI = 0.92-1.25) did not differ significantly between participants allocated vitamin D and those not. All-cause mortality (HR = 1.03; 95% CI = 0.94-1.13), vascular disease mortality (HR = 1.07; 95% CI = 0.92-1.24), cancer mortality (HR = 1.13; 95% CI = 0.91-1.40), and cancer incidence (HR = 1.06; 95% CI = 0.91-1.23) also did not differ significantly between participants allocated calcium and those not. In a post hoc statistical analysis adjusting for compliance, thus with fewer participants, trends for reduced mortality with vitamin D and increased mortality with calcium were accentuated, although all results remain nonsignificant.
Conclusions:Daily vitamin D or calcium supplementation did not affect mortality, vascular disease, cancer mortality, or cancer incidence.
PMID: 22112804