Serum 25-hydroxyvitamin D levels, obesity and the metabolic syndrome among Korean children.
Nutr Metab Cardiovasc Dis. 2012 Jul 2.
Lee SH, Kim SM, Park HS, Choi KM, Cho GJ, Ko BJ, Kim JH.
Department of Family Medicine, College of Medicine, Korea University, Seoul, Republic of Korea.
BACKGROUND AND AIM:
Evidence of the relationship between serum vitamin D levels and cardiovascular risk factors in children is limited. We investigated the associations between serum vitamin D levels (25-hydroxyvitamin D [25(OH)D]) and obesity and metabolic syndrome and its components in Korean children.
METHODS AND RESULTS:
We recruited 1660, nine-year-old, Korean children (904 boys and 756 girls) who voluntarily participated in this study while being examined during school-based health examinations. We measured anthropometric variables (height and weight), metabolic parameters (blood pressure, fasting plasma glucose, triglyceride, and HDL cholesterol levels) and serum vitamin D levels. We analyzed the data using multivariate logistic regression models. Mean 25(OH)D levels were lower in children defined as obese or abdominally obese (P < 0.001). When serum levels of 25(OH)D were divided into quartiles, BMI, waist circumference, and triglyceride levels were lower, and HDL cholesterol levels were higher, as vitamin D levels increased.
Using children from the highest quartile of 25(OH)D levels as a referent, the adjusted ORs (95% CI) for obesity in those in the third, second, and lowest quartiles of 25(OH)D levels were
- 1.55 (1.01-2.40),
- 1.87 (1.22-2.85), and
- 2.59 (1.71-3.90), respectively (P for trend <0.001).
For abdominal obesity the ORs (CI) were
- 2.08 (1.20-3.60),
- 2.32 (1.36-3.95), and
- 2.96 (1.75-5.00) (P for trend<0.001),
and for metabolic syndrome they were
- 2.60 (1.08-6.30),
- 4.00 (1.73-9.26), and
- 4.25 (1.84-9.85), respectively (P for trend <0.05).
CONCLUSIONS:
We found low vitamin D levels in Korean children to be associated with obesity and metabolic syndrome.
Insufficient serum vitamin D levels in children may be a risk factor of obesity and metabolic syndrome.
Copyright © 2012 Elsevier B.V. All rights reserved.
PMID: 22762845
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See also Vitamin D Life
- All items in category Obesity and vitamin D 124 items as of July 2012
- Overview Obesity and Vitamin D
- Korean teens more likely to be obese if have less than 18 ng of vitamin D – June 2012 same department in Korea
- Virtually all young Koreans had less than 30 ng of vitamin D – 2012
- Teen obesity strongly associated with vitamin D deficiency – April 2012
- Obese teens needed 4000 IU of vitamin D - Nov 2011