The effect of vitamin D as supplementary treatment in patients with moderately advanced pulmonary tuberculous lesion.
Acta Med Indones. 2006 Jan-Mar;38(1):3-5.
Nursyam EW1, Amin Z, Rumende CM.
1Departement of Internal Medicine, Faculty of Medicine, University of Indonesia-dr.Cipto Mangunkusumo Hospital, Jakarta.
- People with TB and one geneotype benefited more from 10000 IU of vitamin D - Jan 2011
- Overview Tuberculosis and Vitamin D
- Less likely to catch Tuberculosis if have OK level of vitamin D – Nov 2014
Intervention studies of TB in Vitamin D Life
- TB not treated by average daily 10,000 IU of vitamin D (previous RCTs disagree) – RCT Sept 2017
- Tuberculosis recovery speeded up by single 450,000 IU dose of vitamin D – RCT Jan 2017
- Tuberculosis treatment greatly helped by injection of 200,000 IU of vitamin D – RCT April 2016
- Tuberculosis -100 percent cure rate with 10,000 IU of vitamin D daily – RCT 2006
- Tuberculosis not treated by lots of vitamin D for 16 weeks – RCT Sept 2015
- Every TB patient benefited from 2 doses of 600,000 IU of vitamin D – RCT Jan 2013
- TB treatment helped with Vitamin D – RCT Sept 2012
- Probability of getting TB reduced 60 percent with just 800 IU of vitamin D – RCT Aug 2012
- Overview Tuberculosis and Vitamin D
- Evaluating the vitamin D evidence - Heaney Dec 2010
AIM:
to compare the vitamin D group of pulmonary tuberculosis patients with a placebo group in terms of clinical improvement, nutritional status, sputum conversion, and radiological improvement.
METHODS:
sixty seven tuberculosis patient visiting the Pulmonary Clinic, of Cipto Mangunkusumo Hospital, Jakarta, from January 1st to August 31st, 2001 were included in this study. The subjects were randomised to receive vitamin D (0.25 mg/day) or placebo in a double blind method, during the 6th initial week of Tb treatment. The rate of sputum conversion, complete blood counts, blood chemistry as well as radiologic examination were evaluated.
RESULTS:
there were more male patients than females (39:28), 78.7% were in the productive age group, 71.6% had low nutritional status, 62.4% with low education level, and 67.2% with low income. One hundred percent of the vitamin D group and only 76.7% of the placebo group had sputum conversion. This difference is statistically significant (p=0.002).
CONCLUSION:
the sputum conversion had no correlation with the hemoglobin level, blood clotting time, calcium level, lymphocyte count, age, sex, and nutritional status. There were more subjects with radiological improvement in the vitamin D group.
PMID: 16479024