Neonatal hypocalcemia and its relation to vitamin D and calcium supplementation.
Saudi Med J. 2018 Mar;39(3):247-253. doi: 10.15537/smj.2018.3.21679.
Elsary AY1, Elgameel AA, Mohammed WS, Zaki OM, Taha SA.
Department of Public Health, Faculty of Medicine, Fayoum University, Fayoum, Egypt. E-mail. asmaa_elsary at yahoo.com.
- Mandatory Vitamin D screening for all patients – vitamin D conference in Middle East – March 2017
- Much more than 2,000 IU of vitamin D is needed daily (Middle East studies agree) – meta-analysis Nov 2016
- Vitamin D given to ALL high schools girls in Iran – 75 percent deficiency dropped to 6 percent – April 2016
Items in both categories Infant-Child and Middle East are listed here:
- Turkey needs to give Vitamin D to children too (infants get D for free) – June 2019
- Children in India – 1 in 7 extremely low Vitamin D, 1 in 10 prediabetic – Sept 2019
- All preteen aged girls in India taking 2,000 IU of vitamin D got levels above 20 ng – RCT Nov 2018
- Low levels of Vitamin D in UAE juveniles (virtually none had 30 ng) – Jan 2018
- Saudi infants – 4 in 10 have low Vitamin D, 8 in 10 have low Calcium (hypocalcemia) – March 2018
- Type II Diabetes in children in India increased 4 X in 20 years – Nov 2016
- Newborns in sunny Jordan have very low Vitamin D (histogram) – Nov 2013
- Took 4 months of 400 IU vitamin D for Iranian infants to get serum level of 30 ng – June 2013
- Rickets in 30 percent of infants in India who had low vitamin D – March 2011
- Turkey gave 400 IU vitamin D to all infants and reduced Rickets by 60X - 2011
- Arab pre-term infants often have less than 10 ng of vitamin D - 2010
- Majority of infant seizures in India due to lack of vitamin D - July 2010
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To assess the prevalence of hypocalcemia in outpatient clinic neonates and its relation to vitamin D and calcium supplementation.
Methods: This cross-sectional analytical study was conducted at the University Teaching Hospital from May to October 2016. Data were collected from 100 neonates by interviewing mothers using a structured questionnaire; which included socio-demographic information, maternal and neonatal history; in addition to investigations of serum calcium total and ionized and serum vitamin D level.
Results: The prevalence of hypocalcemia was 76%, late hypocalcemia represent 52% of hypocalcemic neonates. The prevalence of hypovitaminosis D was 38%. Hypocalcemia was found more prevalent among neonates with no history of vitamin D supplementation (98.7%), no history of maternal calcium supplementation (57.9%), while they had a history of neonatal jaundice on phototherapy (46.1%) which increased to 53.8% with late hypocalcemia.
Conclusion: Neonatal hypocalcemia is widely prevalent in Fayoum governorate with significant association with a history of neonatal jaundice on phototherapy, not receiving maternal calcium or neonatal vitamin D supplementation.