Gene problem discovered by taking Vitamin D, sibling had same gene problem – Dec 2019

Example of gene problem running in a family
CYP24A1 problem allowed Vitamin D to accumulate in the body, resulting in hypercalcemia.
It was discovered that a sibling had the same gene problem

• Vitamin D Heritability: twin studies – 20 percent to 85 percent, GWAS 5 percent – Oct 2018
• Health problems that run in families are often associated with low vitamin D
• Health problems can persist through many generations – Epigenetics and Vitamin D

Genetics category listing contains the following

see also

• 384 articles in Vitamin D Receptor
• 141 articles in Vitamin D Binding Protein = GC
• 35 articles in CYP27B1
• Topical Vitamin D
• Nanoemulsion Vitamin D may be a substantially better form
• Getting Vitamin D into your body

Vitamin D blood test misses a lot

• Snapshot of the literature by Vitamin D Life as of early 2019
• Vitamin D from coming from tissues (vs blood) was speculated to be 50% in 2014, and by 2017 was speculated to be 90%
• Note: Good blood test results (> 40 ng) does not mean that a good amount of Vitamin D actually gets to cells
• A Vitamin D test in cells rather than blood was feasible (2017 personal communication)
•    Commercially available 2019
  • However test results would vary in each tissue due to multiple genes
• Good clues that Vitamin D is being restricted from getting to the cells
  1) A vitamin D-related health problem runs in the family
  • especially if it is one of 51+ diseases related to Vitamin D Receptor
  
  2) Slightly increasing Vitamin D show benefits (even if conventional Vitamin D test shows an increase)
  3) Vitamin D Receptor test (<$30) scores are difficult to understand in 2016
  • easier to understand the VDR 23andMe test results analyzed by FoundMyFitness in 2018
  
  4) Back Pain
  • probably want at least 2 clues before taking adding vitamin D, Omega-3, Magnesium, Resveratrol, etc
    • The founder of Vitamin D Life took action with clues #3&4