Retinopathy Linked to Vitamin D Deficiency MedPageToday – with CME
- “In a meta-analysis that included 11 publications and involved studies that included about 6,000 individuals, diabetic patients with vitamin D deficiency were 26.7% more likely to have diabetic retinopathy than patients who were not deficient in the so-called sunshine vitamin (OR 1.267 [95% CI 1.168-1.373, P<0.001]), said Anawin Sanguankeo, MD, a resident in medicine at Bassett Medical Center, Cooperstown, N.Y.”
- . . “annual meeting of the American Association of Clinical Endocrinologists”
- “. . .mean difference of -2.25 ng/mL (95% CI: -3.64 to -0.87, P=0.001),”
- . . “vitamin D deficiency was defined as a serum level less than 20 ng/mL; optimal vitamin D level was defined as a serum level greater than 30 ng/mL.”
 Download the Abstract from Vitamin D Life Publisher wants $36 for the PDF http://dx.doi.org/10.1016/j.jcjo.2016.10.004
Meta-analysis published in 2017 - same 27%, probably the same meta-analysis
__Relationship between vitamin D deficiency and diabetic retinopathy: a meta-analysis
Jason Zhang, MD, Sikarin Upala, MD, MS'Correspondence information about the author MD, MS Sikarin UpalaEmail the author MD, MS Sikarin Upala, Anawin Sanguankeo, MD
DOI: http://dx.doi.org/10.1016/j.jcjo.2016.10.004 |
The purpose of this study was to evaluate the evidence for an association between diabetic retinopathy (DR) and vitamin D deficiency.
Design: Meta-analysis.
Methods: We included 14 observational studies with 10 007 participants who had undergone assessment for both DR and vitamin D deficiency. Pooled odds ratios (ORs) and 95% CIs were calculated using a random-effect, Mantel–Haenszel analysis.
Results: There was a statistically significant association between DR and vitamin D deficiency with an overall pooled OR of 1.27 (95% CI, 1.17–1.37; P = 0.001; I2 = 80%; Pheterogeneity = 0.01). There was also a statistically significant lower serum vitamin D level in patient subgroups with DR versus control groups, with an overall mean difference of –1.32 ng/mL (95% CI, –2.50 to –0.15; P = 0.001; I2 = 89%; Pheterogeneity = 0.01).
Conclusion: There is a statistically significant association between vitamin D deficiency and DR.
Publisher wants $36 for the PDF
See also Vitamin D Life
Overview Diabetes and vitamin D contains the following summary
- Diabetes is 5X more frequent far from the equator
- Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
- Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
- Sedentary people get less sun / Vitamin D
- Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
- Elderly get 4X less vitamin D from the same amount of sun
Elderly also spend less time outdoors and have more clothes on - All items in category Diabetes and Vitamin D
454 items: both Type 1 and Type 2 Vitamin D appears to both prevent and treat diabetes
- Appears that >2,000 IU will Prevent
- Appears that >4,000 IU will Treat , but not cure
- Appears that Calcium and Magnesium are needed for both Prevention and Treatment
- which are just some of the vitamin D cofactors
Number of articles in both categories of Diabetes and:
- Dark Skin
22 ; Intervention 49 ; Meta-analysis 28 ; Obesity 26 ; Pregnancy 39 ; T1 (child) 34 ; Omega-3 10 ; Vitamin D Receptor 18 ; Genetics 10 ; Magnesium 18 Click here to see details - All items in category Diabetes and Vitamin D
454 items - All items in category Vision and Vitamin D
77 items The items in both Diabetes and Vision are listed here:
- Diabetic Retinopathy twice as likely if a T2 Diabetic has low level of vitamin D – meta-analysis March 2017
- Diabetic Retinopathy 2 X more likely if poor Vitamin D Receptor – meta-analysis Nov 2016
- Diabetic Retinopathy 27 percent more likely if low vitamin D – meta-analysis May 2016
- Diabetic Neuropathy sometimes can be reversed by vitamin D
- Worse diabetic vision is associated with low vitamin D or high PTH - Nov 2012
- Diabetics have more retina problems as they have less vitamin D – Sept 2011
Diabetic Retinopathy 27 percent more likely if low vitamin D – meta-analysis May 20162403 visitors, last modified 22 Feb, 2018, This page is in the following categories (# of items in each category) - All items in category Diabetes and Vitamin D