Association between Parathyroid Hormone, 25 (OH) Vitamin D, and Chronic Kidney Disease: A Population-Based Study.
Biomed Res Int. 2017;2017:7435657. doi: 10.1155/2017/7435657. Epub 2017 Mar 7.
Wang WH1, Chen LW2, Lee CC3, Sun CY3, Shyu YC4, Hsu HR3, Chien RN2, Wu IW3.
Seniors (age 58 ± 13) taking part in a national health survey
19.8 % had Chronic Kidney Disease
Comment by Vitamin D Life
It is truly amazing that there are still CKD studies measuring Calcidiol
They should be measuring Calcitriol the output of the kidney, not the output of the liver
Getting Vitamin D into your body has the following chart
Other ways to increase Vitamin D levels in the cells include Omega-3 and UV
See also Vitamin D Life
Kidney category starts with
Kidney category listing hassee also Overview Kidney and vitamin D
Search Vitamin D Life for dialysis OR haemodialysis 878 items not in PDF as of Aug 2020
Search Vitamin D Life for kidney transplant 798 items as of June 2019
"Chronic Kidney Disease" OR CKD 874 items as of Jan 2018
Kidney Intervention trials using Vitamin D:
- Chronic Kidney Disease (stage 3) slowed by 30 ng of Vitamin D and Calcitriol – Dec 2019
- Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT Jan 2019
- Hemodialysis patients (CKD) helped by weekly 50,000 IU of vitamin D – Jan 2017
- Kidney disease helped by active or high dose Vitamin D - Feb 2014
- Peritoneal Dialysis nicely treated by active vitamin D – July 2013
- 7100 IU (50000 weekly) restored vitamin D levels for those with Chronic Kidney Disease – July 2012
- Chronic Kidney Disease reduced with 3600 IU vitamin D (50000 twice a month)– RCT Aug 2012
- Overview Kidney and vitamin D
Overview Kidney and vitamin D contains the following summary
- FACT: Kidney is the primary way to activate vitamin D
- FACT: When the Kidney has problems, there is less active vitamin D (Calcitriol) for the body
- FACT: When the Kidney has problems, there is increased death due to many factors - many of which are associated with lack of Calcitriol
- FACT: There are many on-going intervention clinical trials trying to determine how much of what kind of vitamin D is needed to treat the problem
- FACT: One Randomized Controlled Trial has proven that Vitamin D treats CKD
- FACT: Taking extra Vitamin D, in various forms, does not cause health problems - even if poor kidney
- Suggestion: Increase vitamin D getting into body now - and increase co-factors so that the vitamin D can be better used
Sun, UV lamp, Vitamin D supplement - probably > 5,000 IU,
Calcitriol - which bypasses the need for the kidney to activate vitamin D
Problems with Calcitriol however: typically only lasts for a few hours, also, possible complications
Update: Pre-cursor of active vitamin D made from plants is better than calcitriol – Sept 2012 - Category Kidney and Vitamin D contains
193 items - Kidney disease helped by active or high dose Vitamin D - Feb 2014
- Chronic Kidney Disease reduced with 3600 IU vitamin D (50000 twice a month)– RCT Aug 2012
- Standard oral vitamin D is not a good way to supplement if have Chronic Kidney Disease – March 2016
- Vitamin D for kidney disease – use native or active form – Jan 2016
- 2.4 times more likely to die if have Chronic Kidney Disease and low vitamin D - Sept 2016
- Kidney failure – still debating what form of vitamin D to use – April 2016
- 4X more Chronic Kidney disease patients are now using vitamin D – March 2014
Download the PDF from Vitamin D LifeSeverity (stages) of CKD for the 20% having CKD
Identification of the accurate risk factor for CKD remains mandatory to combat the high prevalence of diseases. Growing evidence suggests the association of serum vitamin D with diverse health conditions. However, the relationship between vitamin D, intact parathyroid hormone (PTH), and calcium-phosphate metabolism and development of CKD remains controversial. We conduct this cross-sectional observational study to investigate the association between serum 25 (OH) vitamin D, intact PTH, and calcium and phosphate levels with eGFR and albuminuria, as a surrogate marker of CKD, in a community population. A total of 4080 participants were recruited. The mean age was 58.4 ± 13.3 years and 1480 (36.3%) were men. The mean eGFR was 94.1 ± 26.3 mL/min/1.73 m2.
The prevalence of CKD was 19.8%. Serum 25 (OH) vitamin D and log intact PTH levels were inversely correlated with eGFR but positively correlated with log albuminuria. Logistic regression analysis identified the log intact PTH as an independent factor associated with eGFR ≤ 60 mL/min/1.73 m2 and proteinuria. This association was consistent when serum intact PTH was analyzed as continuous as well as categorical variables (as hyperparathyroidism). The relationship remains significant using resampling subset analysis with comparable baseline characteristics and adjustment for 25 (OH) vitamin D, calcium, and phosphate levels. This finding warranted further research to clarify the causal relationship of PTH/25 (OH) vitamin D with the risk of CKD in the general population.PMID: 28367447 PMCID: PMC5359435 DOI: 10.1155/2017/7435657
Chronic Kidney disease in 20 percent of seniors in Taiwan – April 2017Printer Friendly PDF this page! Follow this page for updates2388 visitors, last modified 30 Apr, 2017, This page is in the following categories (# of items in each category)