The effect of vitamin D supplement on the score and quality of sleep in 20-50 year-old people with sleep disorders compared with control group.
Nutr Neurosci. 2017 May 5:1-9. doi: 10.1080/1028415X.2017.1317395. [Epub ahead of print]
Majid MS1, Ahmad HS1, Bizhan H1, Mohammad Hosein HZ2, Mohammad A3.
- 1 Dept of Nutritional Science, Paramedical Faculty , Ahvaz Jundishapur Medical Sciences University , Ahvaz , Iran.
- 2 Dept Biostatistics, School of Health , Ahvaz Jundishapur University of Medical Science , Ahvaz , Iran.
- 3 Department of Nutritional Science , Arvand International Division of Ahvaz Jundishapur University of Medical Sciences , Ahvaz , Iran.
Scores would have been much better if the trial has lasted longer than 8 weeks or if they had started with a loading dose
- One pill every two weeks gives you all the vitamin D most adults need
- Poor sleep associated with 2X increase risk of Metabolic problems (both low Vitamin D) – May 2019
- 50,000 IU every 2 weeks, the same as this sleep study
- Sleep disorders cured by 60-80 ng of vitamin D and some B vitamins – March 2013
- Vitamin D improves sleep and reduces pain – review of studies July 2017
- The Better Sleep Vitamin (Vitamin D) – nice 3 dollar book Feb 2015
- Insomnia treatment 12X less likely to be effective if low vitamin D – Oct 2017
- Poor sleep associated with low vitamin D (again) – July 2017
- Poor sleep if low Vitamin D, Magnesium, or Vitamin B6 (NHANES) – June 2019
Description of the study at Examine.com
includes the following data (made into a table by Vitamin D Life)
| Vitamin D | Placebo | |
| Sleep duration | 6.5 hours | 5.2 hours |
| Time to fall asleep | 33 minutes | 59 minutes |
| % of time in bed spent asleep | 87% | 81% |
| Subjective sleep quality Smaller is better | 1.2 | 1.5 |
Download the PDF from SciHub via Vitamin D Life
- Numbers have been reported as percentage or mean ± SD.
- P1: comparison of mean and SD of anthropometric indexes between two groups of vitamin D recipients and placebo recipients (independent sample t-test for hip circumference and weight variables and Mann–Whitney U statistical test for other variables).
- P2: comparison of mean and SD of anthropometric indexes between two groups of vitamin D recipients and placebo recipients after modifying job effect (ANCONA statistical test).
- P3: comparison of mean and SD of anthropometric indices in each group at the beginning and at the end of the study (paired sample t-test for weight, BMI and pelvic circumference variables and Wilcoxon statistical test for other variables).
OBJECTIVES:
Sleep quality may be directly related with vitamin D serum level. Some studies found that people with lower vitamin D serum level experienced a lower sleep quality. Consequently, this study aimed at determining the effect of vitamin D supplements on sleep score and quality in 20-50 year-old people with sleep disorders.
METHODS:
This double blind, clinical trial was performed in November 2015-February 2016 on 89 people with sleep disorders based on Petersburg's Sleep Index. Patient samples were divided randomly into two groups: intervention and placebo. At the end of the study, the data on 89 subjects (44 in intervention group and 45 people in placebo group) were examined. Intervention group received a 50 000-unit vitamin D supplement, one in a fortnight for 8 weeks. Meanwhile, placebo group received placebo. Before and after intervention, Petersburg's Sleep Quality Questionnaire, International Physical Activity Questionnaire, general information questionnaire, sun exposure, vitamin D serum level and 3-day food record questionnaire were assessed and recorded for all participants. To analyze data, t-test, chi square, ANCOVA, U-Mann-Whitney and Wilcoxon statistical tests were used.
FINDINGS:
Based on the results of the present study, at the end of the study sleep score (PSQI) reduced significantly in vitamin recipients as compared with placebo recipients (P < 0.05). This difference was significant even after modifying confounding variables (P < 0.05).
CONCLUSION:
This study shows that the use of vitamin D supplement improves sleep quality, reduces sleep latency, raises sleep duration and improves subjective sleep quality in people of 20-50 year-old with sleep disorder.