Table of contents
- Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies
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5 studies in both categories Falls/Fractures and Magnesium - Vitamin D Life -
10 studies in both categories Bone and Magnesium - Vitamin D Life - Overview Magnesium and vitamin D Has a venn diagram of relationship of Mg and Vit D
- Vitamin D Life – Falls and Fractures category contains
Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies
Nutrients 2023, 15(6), 1304; https://doi.org/10.3390/nu15061304
by Ligia J. Dominguez 1,2,*,Nicola Veronese 1ORCID,Stefano Ciriminna 1,José Luis Pérez-Albela 3,Vania Flora Vásquez-López 3,Santiago Rodas-Regalado 3,Giovanna Di Bella 1,Angela Parisi 1,Federica Tagliaferri 1 andMario Barbagallo 1ORCID
1 Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, 90133 Palermo, Italy
2 Faculty of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy
3 Instituto Bien de Salud, Lima 15036, Peru
Magnesium, an essential cation for numerous cellular processes, is a major component of bone. However, its relationship with the risk of fractures is still uncertain. The present systematic review and meta-analysis aim to investigate the impact of serum Mg on the risk of incident fractures. A systematic search was conducted using several databases including PubMed/Medline and Scopus from inception to 24 May 2022, including observational studies investigating serum Mg and the incidence of fractures considered as outcomes. Abstract and full-text screenings, data extractions, and risk of bias assessments were conducted by two investigators independently. Any inconsistencies were resolved by consensus with a third author. The Newcastle–Ottawa Scale was used to assess the study quality/risk of bias. Among 1332 records initially screened, 16 were retrieved as full-texts; of them, four papers were included in the systematic review with a total of 119,755 participants.
We found that lower serum Mg concentrations were associated with a significantly higher risk of incident fractures (RR = 1.579; 95%CI: 1.216–2.051; p = 0.001; I2 = 46.9%). Our systematic review with meta-analysis suggests a strong association of serum Mg concentrations with incident fractures. Further research is needed to confirm our results among other populations and to assess whether serum Mg is potentially relevant in the prevention of fractures, which continue to increase and represent a significant health burden due to the associated disability.Download the PDF from Vitamin D Life
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5 studies in both categories Falls/Fractures and Magnesium This list is automatically updated
- Muscles improved in women with 50,000 IU vitamin D weekly (8 weeks) plus daily Magnesium – RCT Sept 2020
- Fractures 1.5 X more-likely if low serum Magnesium – meta-analysis March 2023
- Bone fractures occurred twice as often if low Magnesium – April 2017
- Few Fractures if high Magnesium intake – 2X fewer for men, 2.6X for women – June 2017
- 20 percent fewer male hip fractures if more Magnesium in the water – July 2013
Vitamin D Life -
10 studies in both categories Bone and Magnesium This list is automatically updated
- Magnesium helps bones a bit – meta-analysis Jan 2022
- Magnesium increases Vitamin D, which increases Mg. Both increase bone – Oct 2019
- Vitamin D and Calcium do not increase bone density (also need exercise, Mg, K2, protein etc.) – RCT Aug 2019
- Many seniors do not get enough protein, Vitamin D, Mg, etc. needed for bones – Feb 2019
- More Magnesium makes more bone when there is enough Vitamin D (petri dish) – Jan 2019
- Diagnosis and treatment of osteopenia – Holick 2010
- Adding just vitamin D again failed to add bone density (also need Magnesium, Vitamin K, etc) – RCT Aug 2018
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- Stronger bones after 3 generations of tap water (more Ca and Mg) vs bottled water – March 2015
- Bones grow better with high level of magnesium: rat study – Dec 2013
- 20 percent fewer male hip fractures if more Magnesium in the water – July 2013
- Magnesium may be more important to kids’ bone health than calcium – May 2013
- Healthy bones need: Calcium, Vitamin D, Magnesium, Silicon, Vitamin K, and Boron – 2012
- Vitamin D, K2, Magnesium, etc increase bone density when taking together– Jan 2012
- 400 IU of vitamin D Magnesium and Calcium helped Twin bones – Feb 2011
Vitamin D Life - Overview Magnesium and vitamin D Has a venn diagram of relationship of Mg and Vit D
Vitamin D Life – Falls and Fractures category contains
254 items in FALLS and FRACTURES - Vitamin D and Calcium cost-effectively reduce falls and fractures – April 2019
- see also Overview Seniors and Vitamin D
Falls
- Fall prevention - Vitamin D is one of the ways - umbrella review Jan 2024
- Deaths due to falls doubled in just a decade (age-adjusted, perhaps decreased vitamin D) – June 2019
- Preventing Falls in Older Adults – Vitamin D combination is the best - JAMA Meta-analysis Nov 2017
- Falls cut in half by 100,000 IU vitamin D monthly - RCT 2016
- Falls reduced by a third if achieved 40 ng level vitamin D– RCT Sept 2018
- Note: It took 6 months to get to that level. Most trials last only 3 months
- Vitamin D prevents falls – majority of meta-analyses conclude – meta-meta analysis Feb 2015
- Falls reduced by Vitamin D: 13 percent reduction if more than 700 IU – review of 38 trials – Aug 2022
Fracture
- Hip fractures are predicted by 10 factors – low Vitamin D is the biggest – Aug 2023
- Vitamin D and fractures – 24 meta-analyses and counting – Dec 2014
- Low trauma bone fractures in seniors – considering Vitamin D loading dose for all, without testing – Nov 2019
- Vitamin K (any amount and any kind) reduced bone fractures by 24 percent – meta-analysis – May 2019
- 75+ Hip fracture items in Vitamin D Life title Click here for details
Fractures 1.5 X more-likely if low serum Magnesium – meta-analysis March 2023Printer Friendly Follow this page for updates2667 visitors, last modified 08 Mar, 2023, This page is in the following categories (# of items in each category)Attached files
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