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Central Nervous System protection by Vitamin D - Dec 2023

Molecular Regulation of the CNS by Vitamin D
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Molecular Regulation of the CNS by Vitamin D

Physiol Res 2023 Dec 17;72(S4):S339-S356.
L Máčová 1, R Kancheva, M Bičíková

Factors that are up-regulated are marked in green
factors that are down-regulated are in red.
Vitamin D is a lipid-soluble vitamin that can be found in some foods. It is also produced endogenously (in the presence of ultraviolet light), transported through the blood to the targets organs and this is the reason to consider vitamin D as a hormone. It is known that vitamin D has genomic and non-genomic effects.
This review is focused mainly on

the vitamin D receptors,
the importance of vitamin D as a neuromodulator,
the role of vitamin D in the pathophysiology of devastating neurological disorders
- such as Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease and
the benefit of vitamin D and its derivates in alleviating these disorders.

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Central Nervous System protection by Vitamin D - Dec 2023

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