Air pollution decreases Vitamin D levels (while pregnant in this case) – July 2022

Effect of PM2.5 exposure on Vitamin D status among pregnant women: A distributed lag analysis

Ecotoxicology and Environmental Safety Volume 239, 1 July 2022, https://doi.org/10.1016/j.ecoenv.2022.113642
DongjianYangab1LeiChenab1YaYangcJinjingShiabZhenHuangabMengxiangLiabYuechangYangdXinhuaJiab

Background
Serum vitamin D levels are associated with exposure to air pollution, however, the lagged effect of exposure to air pollution remains unknown in pregnant women.

Methods
Pregnant women who delivered at a maternity center in Shanghai, China, from 2015 to 2019 were included in the present study. The concentration of particulate matter 2.5 (PM2.5) before 25-Hydroxyvitamin D [25(OH)D] detection was estimated using the satellite-based grid models. The distributed lag non-linear models were performed to examine the lagged association between weekly-specific PM2.5 exposure and vitamin D deficiency (VDD) or serum 25(OH)D levels.

Results
Among the 58,025 pregnant women included in the study (mean age at conception, 30.77 ± 3.75 years; mean prepregnancy BMI, 21.09 ± 2.55 kg/m2), 61.32% were diagnosed with VDD. Weekly-specific PM2.5 exposure at weeks 1–10 before the detection of 25(OH)D was significantly associated with an increased incidence of VDD (p < 0.05). For every 10 μg/m3 increase in PM2.5 exposure, the serum 25(OH)D level decreased by 1.346 nmol/L (95%CI: 1.183–1.508 nmol/L). The association between average PM2.5 exposure and VDD at 1–10 weeks was more significant in weather conditions with low mean sunshine hours (OR: 1.246, 95%CI: 1.221–1.271).

Conclusion
Our study provided suggestive evidence that PM2.5 exposure at 1–10 weeks before the 25(OH)D detection may decrease the circulating 25(OH)D levels in pregnant women and increase VDD risk in pregnant women. More attention should be paid to the long-term impact of PM2.5, in particular, during weather conditions with a relatively short duration of sunshine.
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Vitamin D Life - Air Pollution reduces Vitamin D contains

Fact: Pollution reduces the amount of time that people are outdoors
Fact: Pollution is often associated with hot temperatures - another reason to not go outdoors
Fact: Less time outdoors results in lower Vitamin D levels
Fact: Pollution attenuates the amount of UVB getting to the skin (but by only a few percent)
Fact:The body's ability to fight Irritation/Inflammation is aided by vitamin D
Fact: All of the types of PM2.5 deaths are also associated with low vitamin D
       Most air pollutions reduce Vitamin D (PM2.5 is worst) – June 2021
Conclusion: Vitamin D supplementation helps the body fight the effects of pollution.

• There were 60+ references in Air Pollution reduces Vitamin D page as of June 2023
• Inhaled vitamin D might turn out to be especially good form as it goes directly to the lungs.

Vitamin D Life - 5 studies in both categories Deficiency and UV

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Map of air quality levels around the world

Real time

Map of PM2.5 levels around the world

Pollution Decreases both 1) UVB 2) Time outdoors