Top 10 chronic health problems of children, women, pregnancies, seniors, and darker skins are fought by Vitamin D

Top 10 chronic health problems of CHILDREN

Rank Chronic Health Condition Prevalence Rate Age Group Key Details
1 Dental Caries (Tooth Decay) 23% - 29% 2-11 years 23% in ages 2-5; 29% in ages 9-11 1 10 19
2 Obesity 12.7% - 20.7% 2-18 years 12.7% (ages 2-5); 20.7% (ages 6-11) 1 6 11
3 Seasonal Allergies 18.9% 0-17 years Boys are more affected (20%) than girls (17.7%) 14
4 Developmental Delays 16-18% School-age Includes various developmental disorders 4
5 ADHD/ADD 11.1% (1 in 9) 5-17 years Approximately 7 million children diagnosed in 2022 4 12
6 Eczema 10.8% 0-17 years Highest in ages 6-11 (12.1%) 14
7 Asthma 8.5% 0-18 years More common in boys (7.0%) than girls (5.4%) 4 16
8 Learning Disabilities 9% School-age Affects academic performance and development 4
9 Food Allergies 5.8% 0-17 years Higher among Black children (7.6%) 14 16
10 Autism Spectrum Disorder 3.2% (1 in 31) 8 years 22% increase since 2020; demographic shift observed 4 13

Top 10 chronic health problems of WOMEN

Perplexity AI June 2025

Chronic Health Problem Incidence/Prevalence in Women
Cardiovascular Disease 44% of women (over 60 million women in the US) 1
Depression 10.4% current prevalence; 36.7% lifetime prevalence 2
Breast Cancer 13% lifetime risk; 316,950 new cases projected for 2025 3
Diabetes 13.7% total prevalence (9.7% diagnosed) 4
Rheumatoid Arthritis Women 3 times more likely than men to develop RA 5
Osteoporosis 19.6% prevalence in women aged 50+ (2017-2018 data) 6
Lupus (Autoimmune Disease) 90% of lupus patients are women; affects 9 out of 10 women vs men 7 8
Asthma/COPD 14.5% asthma prevalence; 42% of women with asthma develop COPD 9
Fibromyalgia 80-96% of fibromyalgia diagnoses are women 10
Migraine 20.7% global prevalence; up to 17% annual prevalence in US women 11 12

Cardiovascular Disease, Depression and Mental Health Disorders, Cancer, Diabetes, Arthritis and Rheumatoid Arthritis, Osteoporosis, Autoimmune Diseases, Chronic Respiratory Conditions, Chronic Pain Conditions, Migraine Headaches

πŸ“„ Entire Perplexity report PDF


Top 10 health problems of WOMEN

Anxiety - Depression 8.7% 1
Type 2 Diabetes 8.0% 2
Dementia 7.4% 3
Ischaemic Heart 6.1% 4
Stroke 3.8% 5
Breast Cancer 3.5% 6
Lung Cancer 3.5% 7
COPD 2.8% 8
Asthma 2.4% 9
Osteoarthritis 2.2% 10

Top 10 surprise costs of Pregnancy if Vitamin D is low

Pregnancy complication Avg. extra cost per pregnancy* (US $) Relative risk reduction at
β‰₯ 40 ng/mL
New cost after vitamin D sufficiency (US $) Cost saved per pregnancy (US $)
Anemia 900 75% lower risk1 225 675
Miscarriage 1 200 49% lower risk vs. deficient
(< 20 ng/mL) 2 3
624 576
Antenatal / Post-partum depression 960 β‰ˆ60% lower risk when 25(OH)D
β‰₯ 40 ng/mL 4 5
384 576
Pre-term birth / labour 15 750 57% lower risk (RR 0.43)
at β‰₯ 40 ng/mL 6 7
6 773 8 978
Gestational hypertension / pre-eclampsia 1 760 45% lower risk with supplementation raising levels to sufficiency 8 9 968 792
Gestational diabetes 1 050 49% lower risk with adequate vitamin D 10 11 536 515
Severe haemorrhage / PPH 1 750 78% lower risk in women with β‰₯ 30–35 ng/mL vs. deficient 12 13 385 1 365
Maternal infections / sepsis 1 350 60% lower neonatal-sepsis risk when mothers are sufficient 14 15 540 810
Hyperemesis gravidarum 240 43% lower risk (MR analysis)16 137 103
Placental disorders (abruption/previa) 800 69% lower risk with sufficiency 1718 19 248 552
  • β€œExtra cost per pregnancy” equals prevalence Γ— average treatment cost.
>40 ng helps a lot
  • Routine screening and targeted supplementation (2 000–4 000 IU D3/day) can reliably raise most pregnant women to β‰₯ 40 ng/mL within 8–12 weeks20.

  • Because cost savings scale with population size, nationwide optimisation of vitamin D status could translate into multi-billion-dollar annual reductions in US maternity expenditures while simultaneously improving maternal-infant outcomes.

    References

  1. https://pmc.ncbi.nlm.nih.gov/articles/PMC4625596/

  2. https://www.grassrootshealth.net/blog/two-new-studies-show-higher-risk-miscarriage-lower-vitamin-d/

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  6. https://pubmed.ncbi.nlm.nih.gov/26554936/

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  20. https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2011/07/vitamin-d-screening-and-supplementation-during-pregnancy

  21. https://pmc.ncbi.nlm.nih.gov/articles/PMC5585545/

  22. https://pmc.ncbi.nlm.nih.gov/articles/PMC10660864/

  23. https://foodandnutritionresearch.net/index.php/fnr/article/view/5574

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  48. https://www.mdpi.com/2227-9067/11/10/1160

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  53. https://www.nature.com/articles/s41387-024-00296-0

  54. https://journals.lww.com/jocn/fulltext/2021/10030/25hydroxyvitaminddeficiencyapotential_risk.2.aspx

  55. https://examine.com/research-feed/study/1wyP49/

  56. https://academic.oup.com/humrep/article/37/10/2465/6644520

  57. https://www.jwatch.org/na32365/2013/09/30/vitamin-d-deficiency-and-risk-sepsis

  58. https://www.contemporaryobgyn.net/view/lack-of-association-found-between-vitamin-d-and-miscarriage-risk

  59. https://www.jcgo.org/index.php/jcgo/article/view/473

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    1. Surprise costs are amortized across healthy pregnancies

calculated as prevalence Γ— average $ per pregnancy for each of the top 10 pregnancy-related health problems:

image

The average extra cost per pregnancy of the top 10 health problems during pregnancy

  • Preterm Birth/Labor clearly emerges as the highest in terms of average extra cost per pregnancy ($15,750), due to both high prevalence and extremely elevated costs associated with neonatal intensive care.

  • Gestational Hypertension/Preeclampsia and Hemorrhage/Severe Bleeding follow, with average extra costs of $1,760 and $1,750 per pregnancy, respectively, reflecting both their moderate prevalence and substantial treatment costs.

  • Miscarriage , Infections/Sepsis , and Mental Health Conditions also contribute notably, with average extra costs ranging from $960 to $1,350 per pregnancy.

  • Gestational Diabetes , Anemia , Placental Problems , and Hyperemesis Gravidarum have more moderate average extra costs per pregnancy, ranging from $240 to $1,050.

This visualization highlights how preterm birth is not only a leading health complication in pregnancy, but also the single greatest cost driver when accounting for both how frequently it occurs and the resources required for management.


    1. Failed to consider

  1. <a href="/pages/top-10-chronic-health-problems-of-seniors-are-all-related-to-low-vitamin-d/">Top 10 chronic health problems of SENIORS</a>

1. Hypertension (High Blood Pressure)

  • Affects 73.7% of women aged 65-74 and 84.1% of women aged 75+ 1

  • 71.8% of men aged 65-74 and 83.2% of men aged 75+ have hypertension 1

  • The most common chronic condition affecting seniors 2

2. High Cholesterol

  • Affects 55.1% of older adults 3

  • Second most frequently reported condition among seniors 3

  • Closely linked to cardiovascular disease risk 2

3. Arthritis

  • Affects 51.3% of older adults 3

  • Third most frequently reported condition among seniors 3

  • 52% of 85-year-olds had a diagnosis of osteoarthritis in clinical studies 4

4. Obesity

  • 38.0% of men aged 60 and older 1

  • 39.6% of women aged 60 and older 1

  • Affects approximately 42% of adults 60 and older 5

5. Diabetes

  • Affects 26% of adults aged 65 and older 6

  • 12.1% of all adults have diabetes, with higher rates among seniors 3

  • Diabetes prevalence among American older adults may increase by more than 400% by 2050 4

6. Heart Disease

  • Affects 6.5% of adults overall, with higher rates among seniors 3

  • Cardiovascular disease and osteoporosis are common chronic conditions at age 85 4

  • Leading cause of death but lower prevalence than other chronic conditions 7

7. Cancer

  • 8.0% of adults overall report cancer (excluding skin cancer) 3

  • Higher incidence rates in older adults, particularly those over 65 3

  • 34% of those above age 65 have been affected by osteoarthritis 6

8. Chronic Obstructive Pulmonary Disease (COPD)

  • 6.2% of adults have COPD 3

  • Chronic respiratory diseases affected 11.7 million adults in 2022 8

  • More common in older populations 4

9. Depression

  • 16% of older adults sought treatment for depression in Medicare data 5

  • 20.2% of all adults report depression 3

  • Not a normal part of aging but significantly affects quality of life 5

10. Stroke (Cerebrovascular Disease)

  • 3.4% of adults report stroke history 3

  • Third leading cause of death among seniors 1

  • Higher incidence with advanced age 4

Hypertension, High Cholesterol, Arthritis, Obesity, Diabetes, Diabetes, Heart Disease, Cancer, COPD, Depression, Stroke


    1. <a href="/pages/perhaps-4000-dollars-annual-less-health-care-costs-if-supplement-with-5-dollars-of-vitamin-d/">$4,000 dollars saved annually for each veteran getting Vitamin D</a>

Some hospitals in the Veterans Administration found $4,000 annual savings per patient when giving Vitamin D

  • image
    • imageData from both US Veterans and Germans (senior)

  1. <a href="/pages/all-of-the-top-10-chronic-health-problems-of-blacks-are-associated-with-low-vitamin-d/">Top 10 chronic health problems of those with DARKER SKIN</a>

1. Hypertension (High Blood Pressure)

  • 56.8% of Black men and 61.0% of Black women aged 20+ have hypertension 1

  • African Americans develop hypertension earlier in life than other groups 2

  • One in three African Americans suffers from high blood pressure 3

2. Obesity

  • 49.6% of African Americans have obesity compared to 42.2% of non-Hispanic whites 4

  • African American women have rates of 56.9% vs. 41.1% for African American men 4

  • Highest obesity rates among all racial groups 4

3. Diabetes (Type 2)

  • African Americans are 60% more likely to be diagnosed with diabetes than white adults 5

  • Over twice as likely to develop diabetes compared to white Americans 6

  • More likely to suffer complications like end-stage renal disease and amputations 7

4. Heart Disease

  • Leading cause of death among African Americans 1

  • African Americans aged 18-49 are two times more likely to die of heart disease 3

  • Young Black patients have an increasing burden of cardiovascular disease risk factors 8

5. Stroke

  • African Americans were 50% more likely to have a stroke than non-Hispanic white adults in 2018 9

  • Black men had stroke death rates 2-3 times higher than other groups 10

  • Higher stroke mortality rates in all regions, especially the South 10

6. Chronic Kidney Disease

  • African Americans are more than 3 times as likely to have kidney failure compared to white Americans 11

  • 18 times greater risk of end-stage renal disease due to hypertension in some regions 12

  • Higher rates of kidney disease requiring dialysis or transplant 12

7. Asthma

  • Black people are 40% more likely to have asthma than white people 13

  • Black women are 84% more likely to have asthma than Black men 13

  • Higher rates of emergency department visits and complications 14

8. Cancer

  • African American men are 50% more likely to get lung cancer 7

  • Higher rates of prostate cancer among Black men 7

  • African American women under 35 are twice as likely to develop cancer 7

9. Depression and Anxiety

  • 20% more likely to experience serious mental health problems 15

  • Depression was the most frequently examined chronic condition (70.2%) in African American families 16

  • Lower rates of mental health treatment utilization 15

10. HIV/AIDS

  • Black people account for 39% of new HIV diagnoses despite being 12% of the population 17

  • HIV incidence rate of 45.0 per 100,000 among Black Americans vs. 5.3 for whites 18

  • Black women account for 55% of new HIV infections among women 18

Hypertension, Obesity, Diabetes, Heart Disease, Stroke, Chronic Kidney Disease, Asthma, Cancer, Depression and Anxiety, HIV/AIDS


  1. <a href="/pages/top-10-causes-of-death-low-vitamin-d-is-associated-with-every-cause/">Top 10 causes of death</a>

2018

image


  1. <a href="/pages/fertility-and-sperm/">Fertility</a> improved if high level of Vitamin D

In Vitro Fertilization


  1. Vitamin D improves the immune system to fight:

  1. Vitamin D Life - <a href="/pages/the-top-10-medical-expenses-can-all-be-decreased-by-vitamin-d/">The top 10 medical expenses can all be decreased by vitamin D</a>
Problem Cost Vitamin D Life
Heart Conditions: $555 Billion Overview Cardiovascular and vitamin D
Diabetes: $245 Billion Overview Diabetes and vitamin D
Cancer: $225 Billion Overview Cancer and vitamin D and 17+ subcategories
Obesity: $190 Billion Overview Obesity and Vitamin D
COPD and Asthma: Between $100-290 Billion COPD fought by Vitamin D - many studies
Overview Asthma and Vitamin D
Traffic Injuries: $99 Billion Vitamin D is needed before most surgeries
Mental Disorders: $89 Billion Overview Alzheimer's-Cognition and Vitamin D
Depression  Brain and Vitamin D - many studies
Low Back and Neck Problems: $87 Billion Back Pain
Joint Disorders: $80 Billion Overview Osteoporosis and vitamin D
High Blood Pressure: $46 Billion Overview Hypertension and Vitamin D

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Tags: Cost savings