Top 10 chronic health problems of children, women, pregnancies, seniors, and darker skins are fought by Vitamin D
Top 10 chronic health problems of CHILDREN
| Rank | Chronic Health Condition | Prevalence Rate | Age Group | Key Details |
| 1 | Dental Caries (Tooth Decay) | 23% - 29% | 2-11 years | 23% in ages 2-5; 29% in ages 9-11 1 10 19 |
| 2 | Obesity | 12.7% - 20.7% | 2-18 years | 12.7% (ages 2-5); 20.7% (ages 6-11) 1 6 11 |
| 3 | Seasonal Allergies | 18.9% | 0-17 years | Boys are more affected (20%) than girls (17.7%) 14 |
| 4 | Developmental Delays | 16-18% | School-age | Includes various developmental disorders 4 |
| 5 | ADHD/ADD | 11.1% (1 in 9) | 5-17 years | Approximately 7 million children diagnosed in 2022 4 12 |
| 6 | Eczema | 10.8% | 0-17 years | Highest in ages 6-11 (12.1%) 14 |
| 7 | Asthma | 8.5% | 0-18 years | More common in boys (7.0%) than girls (5.4%) 4 16 |
| 8 | Learning Disabilities | 9% | School-age | Affects academic performance and development 4 |
| 9 | Food Allergies | 5.8% | 0-17 years | Higher among Black children (7.6%) 14 16 |
| 10 | Autism Spectrum Disorder | 3.2% (1 in 31) | 8 years | 22% increase since 2020; demographic shift observed 4 13 |
Top 10 chronic health problems of WOMEN
Perplexity AI June 2025
| Chronic Health Problem | Incidence/Prevalence in Women |
| Cardiovascular Disease | 44% of women (over 60 million women in the US) 1 |
| Depression | 10.4% current prevalence; 36.7% lifetime prevalence 2 |
| Breast Cancer | 13% lifetime risk; 316,950 new cases projected for 2025 3 |
| Diabetes | 13.7% total prevalence (9.7% diagnosed) 4 |
| Rheumatoid Arthritis | Women 3 times more likely than men to develop RA 5 |
| Osteoporosis | 19.6% prevalence in women aged 50+ (2017-2018 data) 6 |
| Lupus (Autoimmune Disease) | 90% of lupus patients are women; affects 9 out of 10 women vs men 7 8 |
| Asthma/COPD | 14.5% asthma prevalence; 42% of women with asthma develop COPD 9 |
| Fibromyalgia | 80-96% of fibromyalgia diagnoses are women 10 |
| Migraine | 20.7% global prevalence; up to 17% annual prevalence in US women 11 12 |
Cardiovascular Disease, Depression and Mental Health Disorders, Cancer, Diabetes, Arthritis and Rheumatoid Arthritis, Osteoporosis, Autoimmune Diseases, Chronic Respiratory Conditions, Chronic Pain Conditions, Migraine Headaches
π Entire Perplexity report PDF
Top 10 health problems of WOMEN
| Anxiety - Depression | 8.7% | 1 |
| Type 2 Diabetes | 8.0% | 2 |
| Dementia | 7.4% | 3 |
| Ischaemic Heart | 6.1% | 4 |
| Stroke | 3.8% | 5 |
| Breast Cancer | 3.5% | 6 |
| Lung Cancer | 3.5% | 7 |
| COPD | 2.8% | 8 |
| Asthma | 2.4% | 9 |
| Osteoarthritis | 2.2% | 10 |
Top 10 surprise costs of Pregnancy if Vitamin D is low
| Pregnancy complication | Avg. extra cost per pregnancy* (US $) | Relative risk reduction at β₯ 40 ng/mL | New cost after vitamin D sufficiency (US $) | Cost saved per pregnancy (US $) |
| Anemia | 900 | 75% lower risk1 | 225 | 675 |
| Miscarriage | 1 200 | 49% lower risk vs. deficient (< 20 ng/mL) 2 3 | 624 | 576 |
| Antenatal / Post-partum depression | 960 | β60% lower risk when 25(OH)D β₯ 40 ng/mL 4 5 | 384 | 576 |
| Pre-term birth / labour | 15 750 | 57% lower risk (RR 0.43) at β₯ 40 ng/mL 6 7 | 6 773 | 8 978 |
| Gestational hypertension / pre-eclampsia | 1 760 | 45% lower risk with supplementation raising levels to sufficiency 8 9 | 968 | 792 |
| Gestational diabetes | 1 050 | 49% lower risk with adequate vitamin D 10 11 | 536 | 515 |
| Severe haemorrhage / PPH | 1 750 | 78% lower risk in women with β₯ 30β35 ng/mL vs. deficient 12 13 | 385 | 1 365 |
| Maternal infections / sepsis | 1 350 | 60% lower neonatal-sepsis risk when mothers are sufficient 14 15 | 540 | 810 |
| Hyperemesis gravidarum | 240 | 43% lower risk (MR analysis)16 | 137 | 103 |
| Placental disorders (abruption/previa) | 800 | 69% lower risk with sufficiency 1718 19 | 248 | 552 |
- βExtra cost per pregnancyβ equals prevalence Γ average treatment cost.
>40 ng helps a lot
Routine screening and targeted supplementation (2 000β4 000 IU D3/day) can reliably raise most pregnant women to β₯ 40 ng/mL within 8β12 weeks20.
Because cost savings scale with population size, nationwide optimisation of vitamin D status could translate into multi-billion-dollar annual reductions in US maternity expenditures while simultaneously improving maternal-infant outcomes.
References
https://www.grassrootshealth.net/blog/two-new-studies-show-higher-risk-miscarriage-lower-vitamin-d/
https://journals.sagepub.com/doi/full/10.1177/20503121231212093
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2018.00007/full
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.816480/full
https://rep.bioscientifica.com/view/journals/rep/153/5/R163.xml
https://foodandnutritionresearch.net/index.php/fnr/article/view/5574
https://www.grassrootshealth.net/blog/preterm-birth-statistics-reduced/
https://www.sciencedirect.com/science/article/pii/S0261561419330274
https://asean-endocrinejournal.org/index.php/JAFES/article/view/839
https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0180483
https://www.sciencedirect.com/science/article/abs/pii/S0009898122013237
https://www.sciencedirect.com/science/article/pii/S092966462300058X
https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1514148/full
https://jamanetwork.com/journals/jamapediatrics/fullarticle/2681636
https://journals.plos.org/plosmedicine/article?id=10.1371%2Fjournal.pmed.1003973
https://www.sciencedirect.com/science/article/abs/pii/S2405457722002492
https://journals.plos.org/plosmedicine/article?id=10.1371%2Fjournal.pmed.1004260
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2773815
https://www.sciencedirect.com/science/article/pii/S2475299123090728
https://www.sciencedirect.com/science/article/abs/pii/S0261561418300888
https://www.ijrcog.org/index.php/ijrcog/article/download/13754/8526/55226
https://journals.lww.com/jocn/fulltext/2021/10030/25hydroxyvitaminddeficiencyapotential_risk.2.aspx
https://www.jwatch.org/na32365/2013/09/30/vitamin-d-deficiency-and-risk-sepsis
https://www.sciencedirect.com/science/article/pii/S0015028222002588
https://www.sciencedirect.com/science/article/pii/S026156141831197X
https://obgyn.onlinelibrary.wiley.com/doi/10.1111/aogs.14719
https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0080686
https://www.sciencedirect.com/science/article/abs/pii/S0899900714003347
https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1111/aogs.14019
https://journals.lww.com/ebp/fulltext/2021/09000/doesvitaminddeficiencyinpregnancyincrease.28.aspx
https://www.sciencedirect.com/science/article/abs/pii/S2468784723001459
1. Surprise costs are amortized across healthy pregnanciescalculated as prevalence Γ average $ per pregnancy for each of the top 10 pregnancy-related health problems:

The average extra cost per pregnancy of the top 10 health problems during pregnancy
Preterm Birth/Labor clearly emerges as the highest in terms of average extra cost per pregnancy ($15,750), due to both high prevalence and extremely elevated costs associated with neonatal intensive care.
Gestational Hypertension/Preeclampsia and Hemorrhage/Severe Bleeding follow, with average extra costs of $1,760 and $1,750 per pregnancy, respectively, reflecting both their moderate prevalence and substantial treatment costs.
Miscarriage , Infections/Sepsis , and Mental Health Conditions also contribute notably, with average extra costs ranging from $960 to $1,350 per pregnancy.
Gestational Diabetes , Anemia , Placental Problems , and Hyperemesis Gravidarum have more moderate average extra costs per pregnancy, ranging from $240 to $1,050.
This visualization highlights how preterm birth is not only a leading health complication in pregnancy, but also the single greatest cost driver when accounting for both how frequently it occurs and the resources required for management.
1. Failed to considerCaesarean expensive
emotional costs, scores of sleepless nights,
Respiratory infection, children and Vitamin D - many studies
Increased Cancer during childhood - many studies
Sudden Infant Deaths (SIDS) soon after vaccination - many studies
Overview Autism and vitamin D most of the risk factors are reduced by Vitamin D
1. <a href="/pages/top-10-chronic-health-problems-of-seniors-are-all-related-to-low-vitamin-d/">Top 10 chronic health problems of SENIORS</a>1. Hypertension (High Blood Pressure)
Affects 73.7% of women aged 65-74 and 84.1% of women aged 75+ 1
71.8% of men aged 65-74 and 83.2% of men aged 75+ have hypertension 1
The most common chronic condition affecting seniors 2
2. High Cholesterol
Affects 55.1% of older adults 3
Second most frequently reported condition among seniors 3
Closely linked to cardiovascular disease risk 2
3. Arthritis
Affects 51.3% of older adults 3
Third most frequently reported condition among seniors 3
52% of 85-year-olds had a diagnosis of osteoarthritis in clinical studies 4
4. Obesity
38.0% of men aged 60 and older 1
39.6% of women aged 60 and older 1
Affects approximately 42% of adults 60 and older 5
5. Diabetes
Affects 26% of adults aged 65 and older 6
12.1% of all adults have diabetes, with higher rates among seniors 3
Diabetes prevalence among American older adults may increase by more than 400% by 2050 4
6. Heart Disease
Affects 6.5% of adults overall, with higher rates among seniors 3
Cardiovascular disease and osteoporosis are common chronic conditions at age 85 4
Leading cause of death but lower prevalence than other chronic conditions 7
7. Cancer
8.0% of adults overall report cancer (excluding skin cancer) 3
Higher incidence rates in older adults, particularly those over 65 3
34% of those above age 65 have been affected by osteoarthritis 6
8. Chronic Obstructive Pulmonary Disease (COPD)
6.2% of adults have COPD 3
Chronic respiratory diseases affected 11.7 million adults in 2022 8
More common in older populations 4
9. Depression
16% of older adults sought treatment for depression in Medicare data 5
20.2% of all adults report depression 3
Not a normal part of aging but significantly affects quality of life 5
10. Stroke (Cerebrovascular Disease)
3.4% of adults report stroke history 3
Third leading cause of death among seniors 1
Higher incidence with advanced age 4
Hypertension, High Cholesterol, Arthritis, Obesity, Diabetes, Diabetes, Heart Disease, Cancer, COPD, Depression, Stroke
1. <a href="/pages/perhaps-4000-dollars-annual-less-health-care-costs-if-supplement-with-5-dollars-of-vitamin-d/">$4,000 dollars saved annually for each veteran getting Vitamin D</a>Some hospitals in the Veterans Administration found $4,000 annual savings per patient when giving Vitamin D

Data from both US Veterans and Germans (senior)
1. <a href="/pages/all-of-the-top-10-chronic-health-problems-of-blacks-are-associated-with-low-vitamin-d/">Top 10 chronic health problems of those with DARKER SKIN</a>1. Hypertension (High Blood Pressure)
56.8% of Black men and 61.0% of Black women aged 20+ have hypertension 1
African Americans develop hypertension earlier in life than other groups 2
One in three African Americans suffers from high blood pressure 3
2. Obesity
49.6% of African Americans have obesity compared to 42.2% of non-Hispanic whites 4
African American women have rates of 56.9% vs. 41.1% for African American men 4
Highest obesity rates among all racial groups 4
3. Diabetes (Type 2)
African Americans are 60% more likely to be diagnosed with diabetes than white adults 5
Over twice as likely to develop diabetes compared to white Americans 6
More likely to suffer complications like end-stage renal disease and amputations 7
4. Heart Disease
Leading cause of death among African Americans 1
African Americans aged 18-49 are two times more likely to die of heart disease 3
Young Black patients have an increasing burden of cardiovascular disease risk factors 8
5. Stroke
African Americans were 50% more likely to have a stroke than non-Hispanic white adults in 2018 9
Black men had stroke death rates 2-3 times higher than other groups 10
Higher stroke mortality rates in all regions, especially the South 10
6. Chronic Kidney Disease
African Americans are more than 3 times as likely to have kidney failure compared to white Americans 11
18 times greater risk of end-stage renal disease due to hypertension in some regions 12
Higher rates of kidney disease requiring dialysis or transplant 12
7. Asthma
Black people are 40% more likely to have asthma than white people 13
Black women are 84% more likely to have asthma than Black men 13
Higher rates of emergency department visits and complications 14
8. Cancer
African American men are 50% more likely to get lung cancer 7
Higher rates of prostate cancer among Black men 7
African American women under 35 are twice as likely to develop cancer 7
9. Depression and Anxiety
20% more likely to experience serious mental health problems 15
Depression was the most frequently examined chronic condition (70.2%) in African American families 16
Lower rates of mental health treatment utilization 15
10. HIV/AIDS
Black people account for 39% of new HIV diagnoses despite being 12% of the population 17
HIV incidence rate of 45.0 per 100,000 among Black Americans vs. 5.3 for whites 18
Black women account for 55% of new HIV infections among women 18
Hypertension, Obesity, Diabetes, Heart Disease, Stroke, Chronic Kidney Disease, Asthma, Cancer, Depression and Anxiety, HIV/AIDS
1. <a href="/pages/top-10-causes-of-death-low-vitamin-d-is-associated-with-every-cause/">Top 10 causes of death</a>2018

1. <a href="/pages/fertility-and-sperm/">Fertility</a> improved if high level of Vitamin DVitamin D is needed for human fertility β goal is 50 ng β Sept 2018
Infertile patients 1.7X more-likely to become pregnant if take Vitamin D β meta-analysis Feb 2023
If diagnosed infertile, more likely to have live birth if Vitamin D fortification β Feb 2020
Birth rates doubled with Vitamin D - 300,000 IU for infertile men β RCT Nov 2017
Conception was 3.7X more likely if the male had a good level of Vitamin D β July 2022
In Vitro Fertilization
In-vitro Fertilization costs at least 10,000 dollars, Vitamin D costs 5 dollars
In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly β Dec 2024
IVF 4X more successful for white women with lots of vitamin D β many studies
1. Vitamin D improves the immune system to fight:- Glyphosate Addictions Ultra-processed foods Microplastics
99 health problems once every 2 weeks proven to prevent/treat 27 health problems (80% of adults got >40 ng for just $5/year)
Diabetes + Heart Failure + Chronic Pain + Depression + Autism + Breast Cancer + Colon Cancer + Prostate Cancer + BPH (prostate) + Preeclampsia + Premature Birth + Falls + Cognitive Decline + Respiratory Tract Infection + Influenza + Tuberculosis + Chronic Obstructive Pulmonary Disease + Lupus + Inflammatory Bowel Syndrome + Urinary Tract Infection + Poor Sleep + Growing Pain + Multiple Sclerosis + PMS + Schizophrenia + Endometriosis + Smoking**
1. Vitamin D Life - <a href="/pages/the-top-10-medical-expenses-can-all-be-decreased-by-vitamin-d/">The top 10 medical expenses can all be decreased by vitamin D</a>| Problem | Cost | Vitamin D Life |
| Heart Conditions: | $555 Billion | Overview Cardiovascular and vitamin D |
| Diabetes: | $245 Billion | Overview Diabetes and vitamin D |
| Cancer: | $225 Billion | Overview Cancer and vitamin D and 17+ subcategories |
| Obesity: | $190 Billion | Overview Obesity and Vitamin D |
| COPD and Asthma: Between | $100-290 Billion | COPD fought by Vitamin D - many studies Overview Asthma and Vitamin D |
| Traffic Injuries: | $99 Billion | Vitamin D is needed before most surgeries |
| Mental Disorders: | $89 Billion | Overview Alzheimer's-Cognition and Vitamin D Depression Brain and Vitamin D - many studies |
| Low Back and Neck Problems: | $87 Billion | Back Pain |
| Joint Disorders: | $80 Billion | Overview Osteoporosis and vitamin D |
| High Blood Pressure: | $46 Billion | Overview Hypertension and Vitamin D |
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