In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly

Effect of Vitamin D Supplementation in Live Birth Rate of in Vitro Fertilization Outcome

NCT04547530

“Subjects allocated to the vitamin D group will take vitamin D 50,000IU per week from recruitment for 4 weeks, followed by 50,000IU once every 2 weeks throughout the IVF cycle until fetal viability is confirmed at 6 weeks (if pregnant), after which they will be switched to Materna. If not pregnant, they will continue Vitamin D 50,000IU once every 2 weeks until 6 months from randomization, during which they can undergo frozen-thawed embryo transfer.”

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Vitamin D Life comments, references

• Requested update from trial manager, May 2026
• ~2X more successful if also give 50,000 IU to the male as well.
• ~1.5X more succesful if give loading dose of 50,000 IU daily for 7 days (350,000 IU total)
  instead of weekly for just 4 weeks (200,000 IU total)
• Vitamin D greatly improves Fertility
• 50,000 IU of VItamin D every two weeks fights all of the following*
• Ensure a healthy pregnancy and baby - take Vitamin D before conception