Vitamin D Insufficiency Is Associated With Diabetes Risk in Native American Children.
Clin Pediatr (Phila). 2011 Oct 20.
Nsiah-Kumi PA, Erickson JM, Beals JL, Ogle EA, Whiting M, Brushbreaker C, Borgeson CD, Qui F, Yu F, Larsen JL.
University of Nebraska Medical Center, Omaha, NE, USA.
Aims/Hypothesis. Vitamin D insufficiency has not been well studied in Native American (NA) children, who are at risk for obesity and diabetes.
The authors examined vitamin D insufficiency and its association with body mass index (BMI) and insulin resistance.
Methods. In a cross-section of NA children 5 to 18 years old (N = 198), anthropometrics, biomarkers of insulin resistance, and 25-hydroxy-vitamin D concentration [25(OH) vitamin D] were measured. BMI% and homeostatic model assessment of insulin resistance (HOMA-IR) were calculated.
Results. Mean age was 10.8 ± 0.3 years (mean ± SEM). Mean serum 25(OH) vitamin D was 17.8 ± 0.4 ng/mL and 97% had vitamin D insufficiency [25(OH) vitamin D <30 ng/mL]. After adjusting for BMI, 25(OH) vitamin D was inversely associated with HOMA-IR (P < .0001) and several other markers of insulin resistance.
Conclusions/Interpretation. Vitamin D insufficiency was nearly universal in this cohort of NA children and was associated with diabetes and vascular risk markers. Whether vitamin D supplementation can improve insulin resistance must be studied further.
PMID: 22019791
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97% < 30 ng/ml of vitamin D
See also Vitamin D Life
- Overview Dark Skin and Vitamin D
- Overview Diabetes and Vitamin D
- Metabolic Syndrome and vitamin D Diabetes is one of the Metabolic Syndrome diseases
- Suicide rate among Native American teens increasing (yet no mention of low vitamin D) – May 2015
Items in both categories Diabetes and Dark Skin:
- Children in India – 1 in 7 extremely low Vitamin D, 1 in 10 prediabetic – Sept 2019
- Blacks die more often than whites of many diseases (they have less vitamin D) – 2012
- Diabetic blacks – 80 percent had low vitamin D (less than 20 ng) a decade before – Sept 2017
- Diabetes is associated with low vitamin D in various races, but not blacks – Sept 2015
- Diabetes (Type 1) 14X more likely in dark skin children with low levels of vitamin D – May 2015
- Obese diabetics with dark skins not benefit from 6,000 IU of vitamin D daily (no surprise) – RCT March 2015
- Diabetic glycation control is inversely related to Vitamin D in India – Feb 2015
- Type I diabetes in dark skin children associated with low vitamin D if far from equator – Jan 2015
- Dr. Holick video on vitamin D - March 2013
- African-Americans at high risk of obesity and diabetes - 2011
- Type 1 Diabetes associated with low vitamin D, especially in dark skinned youths – Dec 2012
- Hyperglycemia in black veterans is associated with low vitamin D – Nov 2012
- Diabetics with darker skin were more vitamin D deficient – May 2012
- Low vitamin D associated with obesity-related diseases for ethnic minorities – Sept 2011
- 97 percent of Native American children have less than 30 ng of vitamin D – Oct 2011
- Diabetic neuropathy and low vitamin D, especially in blacks - July 2011
- Studies linked low vitamin D and dark skin to Obesity, Diabetes, and heart – June 2011
- Not yet certain that vitamin D reduces cardiovascular and diabetes in blacks – Mar 2011
- Diabetes Statistics including more diabetes with darker skin – 2007
- Insulin resistance correlated with low vitamin D levels in Arab Americans – June 2010
- Insulin sensitivity associated with Vit D in A-A April 2010
- Vitamin D deficiency and insulin insensitivity in African Americans - 2010