What causes a person to be immunocompromized

Perplexity AI answer - Sept 2024

There are several factors that can cause a person to become immunocompromised:

  1. Medical conditions:
    • HIV/AIDS
    • Cancer, especially cancers of the immune system like leukemia
    • Diabetes
    • Multiple myeloma
  2. Genetic disorders:
    • Primary immunodeficiency disorders like severe combined immunodeficiency (SCID)
    • Common variable immunodeficiency (CVID)
    • Chronic granulomatous disease (CGD)
  3. Medications and treatments:
    • Chemotherapy for cancer
    • Immunosuppressive drugs given after organ transplants
    • Long-term use of corticosteroids
    • Radiation therapy
  4. Other factors:
    • Advanced age
    • Malnutrition, especially protein deficiency
    • Lack of sleep
    • Chronic stress
    • Smoking and excessive alcohol consumption
  5. Temporary causes:
    • Recent infections like influenza or mononucleosis
    • Prolonged hospitalization
  6. Removal of immune system organs:
    • Spleen removal (splenectomy)

Being immunocompromised means the immune system is weakened and less able to fight off infections and diseases. This can lead to more frequent, severe, or difficult-to-treat infections. The degree of immunocompromise can vary depending on the underlying cause and may be temporary or long-lasting.


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What Does It Mean to Be Immunocompromised? - NYT Oct 2024

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Tags: Immunity