Vitamin D would probably help both CKD and Kidney transplant (PDF behind paywall)
Native vitamin D in CKD and renal transplantation: meaning and rationale for its supplementation
Journal of Nephrology https://doi.org/10.1007/s40620-024-02055-x $39 paywall
Carlo Alfieri, Paolo Molinari, Simone Vettoretti, Maria Fusaro, Jordi Bover, Giuseppe Cianciolo, Anna Maria Pisacreta, Margherita Di Naro & Giuseppe Castellano
Chronic kidney disease (CKD) poses a significant epidemiological challenge, necessitating effective patient management strategies. Nutritional intervention, particularly vitamin D supplementation, has garnered attention for its potential therapeutic utility in CKD. Despite widespread acknowledgment of the importance of vitamin D, particularly in bone and mineral metabolism, its supplementation in CKD patients for non-skeletal purposes remains contentious due to limited evidence. Hypovitaminosis D linked with CKD substantially contributes to disturbances in mineral and bone metabolism, increasing the risks of cardiovascular complications and skeletal disorders. Notably, CKD patients experience progressive vitamin D deficiency, exacerbating as the disease progresses. Guidelines recommend monitoring 25-hydroxyvitamin D (25 (OH)-D) levels due to their correlation with mineral metabolism parameters, although robust evidence for recommending supplementation is lacking. The primary aim of this paper is to focus on the main open questions regarding vitamin D supplementation in CKD, reporting the current evidence concerning the role of vitamin D supplementation in CKD and in renal transplant recipients.
50 online references include
Vervloet MG, Hsu S, de Boer IH (2023) Vitamin D supplementation in people with chronic kidney disease. Kidney Int 104(4):698–706. https://doi.org/10.1016/j.kint.2023.07.010
Nonskeletal and skeletal effects of high doses versus low doses of vitamin D3 in renal transplant recipients: results of the VITALE (VITamin D supplementation in renAL transplant recipients) study, a randomized clinical trial. Am J Transplant 23(3):366–376 FREE PDF
Lips P, Bilezikian JP, Bouillon R (2019) Vitamin D: giveth to those who needeth. JBMR Plus FREE PDF
Vitamin D Life – Overview Kidney and vitamin D contains
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Vitamin D Life – Chronic Kidney - many studies contains
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