The End of Alzheimer's and Dementia if adjust Vitamin D, B-12, Iron, Omega-3, etc.
End of Alzheimer's books. publications, videos, web - Dale Bredesen
Alzheimer’s Is Now Optional - Dr. Bredesen video and transcript Sept 2023
The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline Aug 2017
The End of Alzheimer's Program: The First Protocol to Enhance Cognition and Reverse Decline at Any Age - with David Perlmutter Amazon Aug, 2020
The First Survivors of Alzheimer's: How Patients Recovered Life and Hope in Their Own Words - Aug 17, 2021
Transcriptional Effects of ApoE4: Relevance to Alzheimer's Disease June 2018
Reversal of cognitive decline in Alzheimer's disease June 2016
Rationale for a Multi-Factorial Approach for the Reversal of Cognitive Decline in Alzheimer’s Disease and MCI: A Review - Jan 2023 https://doi.org/10.3390/ijms24021659 FREE PDF
Personalized Management and Treatment of Alzheimer’s Disease - March 2022 https://doi.org/10.3390/life12030460 FREE PDF
Inhalational Alzheimer's disease: an unrecognized - and treatable - epidemic - 2016
Neuroprotective Herbs for the Management of Alzheimer’s Disease April 2021 FREE PDF
Alzheimer’s disease as a systems network disorder: chronic stress/dyshomeostasis, innate immunity, and genetics Free PDF, 2020
The Ageless Brain: How to Sharpen and Protect Your Mind for a Lifetime Amazon March 2025
Precision Medicine Approach to Alzheimer’s Disease: Successful Proof-of-Concept Trial May 2021 FREE PDF preprint ALL 25 participants improved
his website "ReCODE Analysis Shows 74% Stabilize or Improve"
End of Alzheimer's video and transcript - Oct 2021 100 minutes
Interview of Dr. Bredesen by Dr. R Patrick Oct 2018
- extensive data, hyperlinks, highlights
The First Survivors of Alzheimer's: How Patients Recovered Life and Hope in Their Own Words Aug 2021 Amazon $13
Dr. Gundrie video interview of Dr. Bredesen - including his new book 57 minutes Dec 2021
ReCODE: The Reversal of Cognitive Decline = Mercola 2017
ReCODE: The Reversal of Cognitive Decline Mercola 2017
Story at-a-glance
Dr. Dale Bredesen’s ReCODE protocol evaluates 150 factors known to contribute to Alzheimer’s disease. This identifies your disease subtype or combination of subtypes, and an effective treatment protocol can be devised
Type 1 Alzheimer’s is primarily caused by inflammatory factors; type 2 involves atrophic responses; type 1.5 is a mix of inflammation and atrophy, and type 3 is primarily caused by toxic exposures
Only 5 percent of Alzheimer’s cases are “familial” Alzheimer’s disease, a genetic condition that causes early onset Alzheimer’s; the rest are caused by lifestyle factors over which we have a great deal of control; hence, we have the ability to improve or even reverse most cases of the disease
Includes interview and transcript of Dr. Bredesen, author
4 Alzheimer’s Subtypes
While these classifications have not become widely accepted yet, Bredesen has published two papers on Alzheimer’s subtypes, based on metabolic profiling.4 These include:
1. Type 1 , inflammatory ( “hot” ) Alzheimer’s: Patients present predominantly inflammatory symptoms. They have high-sensitivity C-reactive protein, interleukin 6 and tumor necrosis factor alpha, reflecting a chronic inflammatory state. When the NF-ĸB part of inflammation is activated, it also alters gene transcription. Two of the genes turned “on” are beta-secretase and gamma-secretase, the latter of which cleaves APP, thereby promoting synaptoclastic processes.
2. Type 1.5, glycotoxic (sugar-toxic, “ sweet , a mixed subtype: This is an in-between subtype that involves both inflammation and atrophy processes, due to insulin resistance and glucose-induced inflammation.
3. Type 2, atrophic or “ cold ”Alzheimer’s: This is classified as patients presenting an atrophic response. While a completely different mechanism from inflammation, it produces the same end result — it pushes APP in the direction of creating amyloid plaques and Alzheimer’s cell signaling.
4. Type 3, toxic (“ vile ”) Alzheimer’s: These are patients with toxic exposures. Many will have chronic inflammatory response syndrome (CIRS) markers, even though most do not fit the official criteria for CIRS. “They act like CIRS patients (in their labs, not necessarily symptoms) with dementia,” Bredesen explains.
Sections of the article include
If You’re ApoE4 Positive, Fasting Is Strongly Indicated to Avoid Alzheimer’s
Mitochondrial Dysfunction Is at the Heart of Alzheimer’s
The ReCODE protocol evaluates 150 different variables, including biochemistry, genetics and historical imaging, to determine which factors are most likely driving the disease.
Alzheimer’s Screening Tests
| Test | Recommended range |
| Ferritin ( Iron ) | 40 to 60 ng/mL |
| GGT | <16 U/L for men and < 9 U/L for women |
| 25-hydroxy vitamin D | 40 to 60 ng/mL |
| High-sensitivity CRP | <0.9 mg/L |
| Fasting Insulin | < 4.5 mg/dL |
| Omega-3 index and Omega 6:3 ratio | Omega-3 index > 8 % |
| TNF alpha | < 6.0 |
| TSH | Less than 2.0 microunits/mL |
| Free T3 | 3.2-4.2 pg/mL |
| Reverse T3 | <20 ng/mL |
| Free T4 | 1.3-1.8 ng/mL |
| Serum copper and zinc ratio | 0.8-1.2 |
| Serum selenium | 110-150 ng/mL |
| Glutathione | 5.0-5.5 ÎĽm |
| Vitamin E (alpha tocopherol) | 12-20 mcg/mL |
| Body mass index | 18-25 |
| ApoE4 (DNA test) | See how many alleles you have: 0, 1 or 2 |
| Vitamin B12 | 500-1,500 |
| Hemoglobin A1c | Less than 5.5 |
| Homocysteine | 4.4-10.8 mcmol/L |
Annual summit on Alzheimer's prevention (June 2023, etc.)
FREE?
Nov 2021 email from End of Alz organization - details and pricing
đź“„ Download the PDF from Vitamin D Life
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Bredesen protocol and Parkinson's
Dr. Dale Bredesen & Karl Sterling Discuss “The End of Alzheimer’s Program” Video July 2021
"Sterling, a neurorehabilitation specialist who focuses on Parkinson’s, and Dr. Bredesen discussed the mechanisms behind cognitive decline and the need to “flip the script” on the current approach of treating diseases Alzheimer’s, Parkinson’s, Lewy Body Dementia, and other forms of neurodegeneration using a precision medicine approach that identifies an individual’s contributors and establishes a treatment plan that reverses symptoms and prevents these diseases"
Episode 5 – Dr. Dale Bredesen and Dr. Craig Tanio on the Prevention of Cognitive Decline unknown date
- "Today, Dr. Craig Tanio, Dr. Dale Bredesen and I will all be discussing multi-modal approaches to neurocognitive decline, his latest research study on Alzheimer’s disease, his upcoming books, mechanisms into Alzheimer’s disease, ALS, Parkinson’s disease , macular degeneration, and much more."
The First Survivors of Alzheimer's by Dr. Dale Bredesen Aug 2021
- "...the potential for adapting the successful Alzheimer's protocol to other diseases such as Parkinson's disease and macular degeneration"
REVERSAL OF ALZHEIMER’S DISEASE WITH DR. DALE BREDESEN: RATIONAL WELLNESS PODCAST 209 May 2021
26:31 The conditions that are associated with cognitive decline include the following:
. Alzheimer’s disease, the most common form.
. Lewy Body Disease.
Parkinson’s.
Vascular dementia.
Normal pressure hydrocephalus. etc.
Frontotemporal dementia,
LATE. Limbic-predominant age-associated TDP-43 encephalopathy.
Multiple Sclerosis.
PSP. Progressive supranuclear palsy.
Corticobasal degeneration.
CTE, which is chronic traumatic encephalopathy.
TBI. Traumatic brain injury.
Post-COVID-19 related encephalopathy? Long haul?
Vitamin D Life - Overview Alzheimer's-Cognition and Vitamin D start with
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See also Vitamin D Life
Comparing High-dose vitamin D therapies one column is The End of Alzheimer's
Vitamin D reduces Alzheimer’s disease in at least 11 ways – Jan 2013
Genes which reduce blood-level vitamin D increase the risk of Alzheimer’s disease – Dec 2016
Alzheimer’s patients 3X more likely to have a malfunctioning vitamin D receptor gene – 2012
Alzheimer’s (apoE4) may require more than Omega-3 - May 2017
Cognitive Impairment 1.8 times more likely if low Omega-3– Oct 2016
Schizophrenia relapses reduced 3X by Omega-3 – RCT Mar 2015
Cognition of Alzheimer’s patients improved by daily 4,000 IU of vitamin D – RCT Jan 2015
Poor cognition 26 percent more likely if low Vitamin D (29 studies) – meta-analysis July 2017
Cognitive category starts with the following
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See also web
Reverse Alzheimer's With The Bredesen Protocol - ReCODE MyBioHack Feb 2020
The 3 Vitamins that Prevent Brain Loss Aug 2017
- "Our body can detoxify homocysteine, though, using three vitamins: folate, vitamin B12, and vitamin B6"
- " B-vitamin treatment reduces, by as much as seven-fold] the brain atrophy in the regions specifically vulnerable to the Alzheimer’s disease process."
Reversal Of Cognitive Decline Using Network Medicine - Dale Bredesen, MD Video, 2022 107 minutes