Sepsis is fought by Vitamin D in 9 ways

Vitamin D Deficiency: An Underestimated Factor in Sepsis?

Int. J. Mol. Sci. 2023, 24(3), 2924; https://doi.org/10.3390/ijms24032924

by Charlotte Delrue 1,Reinhart Speeckaert 2,Joris R. Delanghe 3 and Marijn M. Speeckaert 1,4, Belgium

Vitamin D is an important immune modulator that is linked to infection susceptibility. It has been suggested that vitamin D deficiency plays a role in sepsis and septic shock because vitamin-D-related pathways are associated with various immunological, endocrine, and endothelial functions. Previous research has yielded inconclusive results regarding the link between mortality and vitamin D deficiency in sepsis patients. In patients with sepsis and severe vitamin D deficiency, an adequate vitamin D concentration may reduce mortality. Randomized controlled trials to assess the influence of vitamin D supplementation on clinical outcomes in sepsis patients with vitamin D deficiency are uncommon. We will provide an overview of the current knowledge about the relationship between vitamin D and sepsis in this review, as well as consider the potential value of vitamin D supplementation in this situation.

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Vitamin D Life - Sepsis is both prevented and treated by Vitamin D - many studies contains

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