Poor sleep if low Vitamin D, Magnesium, or Vitamin B6 (NHANES)

Created June 2019

Analysis of NHANES 2005-2016 Data Showed Significant Association Between Micro and Macronutrient Intake and Various Sleep Variables

Curr Dev Nutr. 2019 Jun 13;3(Suppl 1). pii: nzz031.P06-103-19. doi: 10.1093/cdn/nzz031.P06-103-19. eCollection 2019 Jun.

Note: Vitamin B6 improves digestion, which may increase bio-availability of both Vitamin D and MagnesiumSearch Vitamin D Life for (sleep OR insomnia) Magnesium 228 items as of June 2019* Poor sleep 1.5 X more likely if less than 20 ng of Vitamin D – Feb 2019* Sleep may be regulated by Vitamin D via two pathways – Nov 2018* Children short sleep 12 percent more likely for each 1 ng lower vitamin D at birth – Oct 2018* Sleep problems cured by vitamin D, etc. – workshops and patient workbooks – Gominak 2018* Sleep, Vitamin D, B Vitamins, jaw, etc. Dr. Gominak transcript - 2016* Insomnia treatment 12X less likely to be effective if low vitamin D – Oct 2017* Sleep disorders nicely treated by Vitamin D (50,000 IU twice a month) – RCT May 2017* Sleep Apnea patients – 98 percent had low vitamin D – Feb 2016

Note: there appears to be no study for this abstract

Ikonte C1, Reider C2, Fulgoni V 3rd3, Mitmesser S1.

1 Pharmavite LLC.

2 Pharmavite.

3 Nutrition Impact LLC.

OBJECTIVES: To understand the association between micro and macronutrient intake and sleep variables from the National Health and Nutrition Evaluation Survey (NHANES, 2005-2016).

METHODS:

Data analysis was performed using SAS 9.4; regression analysis was used to assess the relationship (p < 0.05) of nutrient intake with sleep variables. All nutrients were individual usual intakes determined using the National Cancer Institute method from food plus supplements; covariates included age, gender, ethnicity, poverty income ration, current smoking status and physical activity level. Individuals 16+ years of age were included in the analysis; pregnant or lactating females and those with unreliable dietary recalls were excluded in the analysis. Seven (7) Sleep variables included in the analysis were short sleep hours (<7 hrs of sleep) and trouble sleeping (NHANES 2005-2016), sleep disorder (NHANES, 2005-2014) and poor sleep quality, insomnia, sleep latency, and use of sleeping pills >5 times in the last month (NHANES 2005-2008).

RESULTS:

In adults (males and females) 19+ years,

  • 32.7% experienced short sleep;

  • 47.3% poor sleep quality;

  • 8.94% a sleep disorder;

  • 37.9% sleep latency;

  • 9.30% used sleeping pills;

  • 15.1% exhibited insomnia; and

  • 27.7% experienced sleep trouble.

Within this population, short sleep was significantly (p < 0.05) associated with the greatest number of nutrients; showing an inverse association with

  • magnesium,

  • niacin,

  • vitamin D ,

  • calcium, and

  • dietary fiber intake.

Across all seven sleep variables , however,

  • magnesium,

  • niacin and

  • vitamin D

demonstrated significant (p < 0.05) inverse association within this population.

Inverse associations were also found for

  • dietary fiber intake and short sleep and sleep disorder;

  • phosphorus intake and poor sleep quality,

  • sleep latency and sleep pill use; and

  • vitamin K intake and poor sleep quality, sleep disorder, sleep latency and sleep pill use in the gender combined adults 19+ years.

Within this population however, there were direct associations for the intakes of protein and vitamin B6 and short sleep, sleep disorder and sleep trouble; for the intakes of sodium and vitamin A and poor sleep quality, sleep latency and sleep pill use; for the intake of vitamin B12 and poor ADL and insomnia; and for the intake of zinc and sleep quality, sleep latency, sleep pill use, poor ADL and insomnia.

Among female adults 19+ years, dietary fiber was the only nutrient that showed an inverse association with all seven sleep variables .

CONCLUSIONS: These findings demonstrate the importance of micro and macronutrient intake on numerous sleep variables.

FUNDING SOURCES : This analysis was funded by Pharmavite, LLC.

PMID: 31223980 PMCID: PMC6574146 DOI: 10.1093/cdn/nzz031.P06-103-19