Overview: Omega-3 many benefits include helping vitamin D
Vitamin D and Omega-3 category has items
Omega-3 and Vitamin D separately and together help with Depression, Cardiovascular, Cognition, Pregnancy, Infant, Obesity, Mortality, Breast Cancer, . . .

There are many books on Omega-3: I such as: The Omega-3 Effect
Everything you need to know about the supernutrient for living longer, happier, and healthier
Willian Sears, 2012 Amazon $6 Kindle
Omega-3 content of 3 ounces of (wild, not farmed) fish (150 to 1,900 mg)
Mackerel (Atlantic & Pacific): 1,900 mg EPA + DHA
Herring: 1,330 mg EPA + DHA
Anchovies: 1,200 mg EPA + DHA
Sablefish (Black Cod): 1,200 mg EPA + DHA
Salmon (Atlantic, Chinook, Coho): 1,200 mg EPA + DHA
Sardines (Atlantic & Pacific): 900 mg EPA + DHA
Swordfish: 643 mg EPA + DHA
Trout: 621 mg EPA + DHA
Chat-GPT Dec 2023
Atlantic cod - cooked ~200 mg
Atlantic cod - cooked, farm-raised ~150 mg
Natures Sunshine Omega-3 vs Mercury

Need to take standard Omega-3 with a fatty meal - Google Bard Dec 7, 2023
Does a person need to take Omega-3 with a fatty meal when the Omega-3 is in oil?
Yes, taking Omega-3 oil with a fatty meal is generally recommended for optimal absorption. This is because omega-3 fatty acids are fat-soluble, meaning they require the presence of fat in the digestive system to be properly absorbed into the bloodstream.
Here's why:
Bile acids: A high-fat meal stimulates the production of bile acids by the liver. These bile acids help to emulsify and break down fats, making them easier for the body to absorb. This includes omega-3 fatty acids present in the oil.
Micelles: Bile acids form micelles around the omega-3 fatty acids, creating a water-soluble complex that can be transported through the digestive system and absorbed into the bloodstream.
Absorption rate: Studies have shown that taking omega-3 supplements with a fatty meal can significantly increase their absorption rate compared to taking them on an empty stomach.
Therefore, while you can still absorb some omega-3 oil without a fatty meal, taking it with a meal containing healthy fats like avocado, nuts, seeds, or fatty fish will significantly improve its absorption and maximize its potential health benefits.
Here are some additional tips for taking Omega-3 oil with a fatty meal:
Take the oil at the beginning of the meal, as this allows for better absorption.
Choose a meal that is naturally high in healthy fats.
Avoid taking omega-3 oil with alcohol or caffeine, as these can interfere with absorption.
Of course, it's always best to consult with your healthcare provider for personalized advice regarding the most effective way to take omega-3 supplements for your specific needs.
Emulsified Omega-3 does NOT need a fatty meal: Perplexity AI - May 2024
No, emulsified omega-3 supplements do not need to be taken with fatty meals to be effectively absorbed. Emulsified omega-3 supplements are designed to enhance the bioavailability of omega-3 fatty acids, such as EPA and DHA, without the need for concurrent high-fat meal consumption. This is achieved through the use of self-micro-emulsifying delivery systems (SMEDS) and other emulsification technologies that simulate the emulsification process of bile, facilitating the absorption of omega-3 fatty acids in the absence of dietary fats.
Research has shown that emulsified forms of omega-3 supplements can significantly increase the absorption of EPA and DHA compared to non-emulsified forms, even when consumed in a fasted state or with low-fat or no-fat meals. For instance, a study demonstrated that a novel SMEDS formulation of omega-3 fatty acids resulted in a more than 6-fold increase in absorption compared to control conditions, highlighting the effectiveness of emulsification in enhancing bioavailability under various dietary conditions 1.
Additionally, other studies have corroborated these findings, indicating that emulsified fish oil supplements lead to enhanced absorption of omega-3 fatty acids compared to traditional capsular forms, without the need for a high-fat meal 6 7. This makes emulsified omega-3 supplements particularly beneficial for individuals who are advised to limit their fat intake or find it inconvenient to coordinate their supplement intake with fatty meals.
In summary, emulsified omega-3 supplements are specifically formulated to improve the bioavailability of omega-3 fatty acids without the necessity of accompanying fat intake, making them a convenient option for various dietary preferences and conditions 1 67.
The founder of Vitamin D Life takes Omega-3 emulsion: Coromega
Re-esterified triglyceride form of Omega-3 is about 70% more bioavailable than standard
Popular ones: Viva Naturals, MacuHealth, Fortifeye, Viactiv, and Nordic Naturals (some, not all of their products)
Emulsified Omega-3 (Coromega) is about 300% more bioavailable than standard
Notes by Admin of Vitamin D Life Dec 2012
Aroma of food is stored in the fat.
Certain fats are much more likely to go rancid than others and develop off flavors.
Animals tend to store excess energy in fat.
Linolenic acid in 10X less stable than linoleic acid: This form of Omega-3 has a short shelf life discovered 1952
Israel is the top consumer (per person) of Linoleic acid in the world (30 grams), and have a high rate of heart attack, similar to the US, but with less meat.
Greens are high in Omega-3
Should have a low ratio of Omega-6 to Omega 3: US has a high ratio of 10, Sweden has 5, Japan has only 2
- Japan has highest life expectancy AND highest Omega-3 consumption in the world (as well as a very high consumption of Vitamin K2)
PUFA was the only way to describe all Omegas until 1964
Ratios in foods: Flaxseed oil 0.2, Canola 2, Walnut 5, Corn 46
Far less saturated fat in wild animals than domesticated (1968)
Omega-3 reduced future heart attacks in Intervention clinical trials
- Intervention trial with 11,000 people who already had a heart attack. DHA and EPA 850 mg or placebo.
- Within 3 years 45% fewer Sudden Deaths due to subsequent heart attacks.
Additional thoughts from reading The Queen of Fats
- Omega-3 promoters encounter even more resistance than do Vitamin D3 promoters
- Economic resistance from the food industry (shelf life) only Omega-3, medical industry opposed to change: Omega-3 and D3
- Wonder – do Americans pay more on health care than they do on food?
- Answer YES: 16% on health care and 10% on food - as % of disposable income or % of GDP Breakdown by income level
- 40 years ago the %s of O-3 and O-6 were almost reversed.
The goal of eating a balanced diet without supplements no longer makes sense when our food is no longer balanced
Perspective of the importance of Vit D and co-factors to health

Vitamin D Life - Omega-3 associations with other categories
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See also Vitamin D Life
() items in category Omega-3 and Vitamin D
Typical pregnancy is now 39 weeks – Omega-3 and Vitamin D might restore it to full 40 weeks
Infants getting 1 g of Omega-3 for 12 weeks got better brains – RCT March 2017
Vitamin D Cofactors in a nutshell by Vitamin D Life
Overweight women on caloric restriction diet got 3X benefits from 8 weeks of Omega-3 – RCT Dec 2015
2.7 fewer days in hospital after surgery if had taken Omega-3 (19 RCT) – meta-analysis – June 2017
Sepsis: 4 fewer days in ICU if add Omega-3 – meta-analysis of 12 RCT – June 2017
Consuming more monounsaturated fat increased vitamin D – Aug 2011 has the following
- WikiPedia Good (more vitamin D into bloodstream)= much more BLUE than Green


Almonds and macadamia nuts are examples of good foods to take with vitamin D
Omega-3 product
How To Choose OMEGA-3 Supplements ( Buyer's Guide ) 17 minute Video -Nov 2023
Simple review of >300 Omega-3 products, no mention about bioavailability 2021
https://labdoor.com/rankings/vegan-omega-3 Labdoor 2017? VEGAN
Omega-3 Chewable 400+ items on Amazon Jan 2023
Fish Oil Supplements – Omega-3 Benefits, Side Effects, Dosage & Best Brand
Omega-3 Supplement Guide: What to Buy and Why Dec 2015 Healthline
- Describes ~10 forms
- Fish Oil Review by Consumer Labs Dec 2023 (behind a paywall)
- Consumer Labs offers a 5 day free trial
- 82 page excellent report of 2017 had the following table of contents (updated Dec 2023)

- Statins tended to cancel the benefits of Omega-3
- Emulsiified forms had 3X to 8X more bioavailability when taken with low fat meal (no indication of bioavailability with high fat meal)
- Discusses a huge number of health problems helped by Omega-3: arthritis, gout, ulcerative colitis, dry eye, colorectal cancer, weight loss due to chemotherapy, eye diseases, anxiety, stress, migraine headache, schizophrenia, epilepsy, reading skills, pregnancy, wheezing, cognition, muscle strength
- Dose sizes ranged from 60 mg (children) to 1,460 mg/day
- No difference noticed in prescription forms - other than price
1. See also Omega-3 testingOmega-3 is vital for health, mail-in test is low cost and accurate $43 Fall 2016
- $55 for Omega-3 Index, $80 adds Omega-6/Omega-3 ratio + AA/EPA ratio + transfat index
- They also have a Calculator - input your current index and goal index
1. * <a href="/pages/omega-6-blocks-omega-3-etc-many-studies/">Omega-6 blocks Omega-3 etc. -many studies</a> 1. See also web- Includes Omega-3 extends life by 4.7 years (Framington Heart Study)
Eating fish during pregnancy may boost baby's development, not impair it Medical News today Jan 2015
- Omega-3 may counteract the inflammatory effect of mercury Children followed for 20 years
61 Health Benefits of Omega-3 Fatty Acids Green Med Info Jan 2012
What’s in Your Fish Oil Supplements? New York Times Jan 2014
- Includes reporting on results by LabDoor: accuracy, quality, etc of about 100 fish oil/mega-3 products
- THE HISTORY OF OMEGA 3 LiveStrong March 2011
- Govt recommendations since 1995
History of omega-3s since 1923
TAKE OMEGA 3 UK, lots of reference
Low omega-3 levels could explain why some children have reading problems Sept 2013
- Every one of 493 of the UK kids with cognitive disabilities had low levels of Omega-3
- *PDF is attached at the bottom of this page
- Lard from pigs which never get outdoors has very little vitamin D**
- "Free range" lard has 500 IU vitamin D per teaspoon rare, but you can get it on the internet, etc
- Are Statin Drugs Killing The Health Benefits Of Omega-3 Fat? Green Info Jan 2013
- discussion of BMC study published in Jan 2013: those taking statins to no get heat benefits of Omega-3 full text online
600 mg DHA allowed children underperforming in reading to sleep 1 more hour per night RCT March 2014
Update on Essential Fats Suillivan, 2011 has the following graph

- Huge list of studies of benefits of Omega-3 - sorted by health problem Expertomega3
- 2. OMEGA-3 IN INFLAMMATORY PROCESSES - Obesity. Metabolic syndrome, Diabetes, Rheumatoid arthritis, IBD, Periodontitis
- 3. OMEGA-3 AND THE CARDIOVASCULAR SYSTEM - Blood pressure, Sudden death. Plasma lipids, Platelet aggregation, Arteriosclerosis, Arrhythmias, Atrial fibrillation
- 4. OMEGA-3 IN GESTATION, BREASTFEEDING AND INFANCY - Prevention of preterm birth, Pre-eclampsia, Premature infants, etc
- 5. OMEGA-3 IN GYNAECOLOGY
- 6. OMEGA-3 AND BEHAVIOURAL AND MENTAL DISORDERS - ADHD, Depression, Autism, Bipolar disorder, Borderline personality, Substance abuse, Psychotic disorders
- 7. OMEGA-3 AND CANCER
- 8. OMEGA-3 IN ADULT COGNITION
- 9. OMEGA-3 AND HEARING LOSS
- 10. OMEGA-3 AND VISION, etc
- Organic Meats have 50% more Omega-3 - meta-analysis Feb 2016 NYT
- switching to organic meats only adds about 50 mg of Omega-3 - which is not very much
- And Omega-6 was slightly lower in organic meats
- Cooking oils compared
- InformationIsBeautiful.net March 2016
- Here is a tiny portion of their analysis

1. See also PubMed- The role for dietary omega-3 fatty acids supplementation in older adults Oct 2014
- 📄 Download the PDF from Vitamin D Life.
Evidence-based nutritional advice for patients affected by age-related macular degeneration Feb 2014, free text online
Role of omega-3 Fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials May 2014, free text online
U.S. adults are not meeting recommended levels for fish and omega-3 fatty acid intake: results of an analysis using observational data from NHANES 2003-2008 April 2014, free text online
Helping women to good health: breast cancer, omega-3/omega-6 lipids, and related lifestyle factors March 2014, free text online
ω-3 PUFAs in the Prevention and Cure of Inflammatory, Degenerative, and Neoplastic Diseases. Biomed Res Int. free full text online
Cochraine review found that PUFA reduced MS relapses Dec 2012
Impact of ω-3 fatty acids in Parkinson's disease. PubMed Sept 2011
- Association between fish consumption, long chain omega 3 fatty acids, and risk of cerebrovascular disease:
- systematic review and meta-analysis Oct 2012
Omega-3 fatty acids, insulin resistance and type 2 diabetes Oct 2011 free text online
Association between fish consumption, long chain omega 3 fatty acids, and risk of cerebrovascular disease: systematic review and meta-analysis free text online
Fetal and neonatal levels of omega-3: effects on neurodevelopment, nutrition, and growth 2012 free text online
Celiac disease, inflammation and oxidative damage: a nutrigenetic approach. April 2012
Docosahexaenoic acid (DHA): an ancient nutrient for the modern human brain. May 2011
Omega-3 fatty acids modify human cortical visual processing--a double-blind, crossover study. 2011
10-year cognition in preterms after random assignment to fatty acid supplementation in infancy. Oct 2011
Long-chain omega-3 polyunsaturated fatty acids may be beneficial for reducing obesity-a review.
- Dec 2010 PDF is attached at bottom of this page - it has the following graph of fat loss vs type of fat

- Dietary interventions for multiple sclerosis. Cochrane Dec 2012
- Review of many RCT - Omega-3 reduced MS relapases by 18%, but was not statistically significant
- Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study Sept 2014
- 1080 mg eicosapentaenoic acid+docosahexaenoic acid) was associated with a 33.6% reduction in seizure frequency
- 2000 mg was similar to placebo - no reduction
1. PubMed: Omega-3 Cardio__Omega-3 polyunsaturated fatty acids and cardiac rhythm: an introduction. 2012 full text online
Are the anti-arrhythmic effects of omega-3 fatty acids due to modulation of myocardial calcium handling? 2012 free text online
Omega-3 for patients with cardiovascular disease Nov 2012 free text online
Omega-3 polyunsaturated fatty acids and cardiac rhythm: an introduction. Dec 2012 full text online
- After almost 20 years, still no consensus
Omega-3 index and cardiovascular health Feb 2014 free text online
Omega-3 Fatty acids: anti-arrhythmic, pro-arrhythmic, or both? 2012
Effect of omega-3 polyunsaturated fatty acids and vitamin D on cardiovascular diseases Feb 2014,
- 📄 Download the PDF from Vitamin D Life__


1. PubMed: Omega-3 BrainOmega-3 polyunsaturated fatty acids in the brain: metabolism and neuroprotection. PubMed June 2011
A nutrient combination that can affect synapse formation April 2014, free text online
The older people, omega-3, and cognitive health (EPOCH) trial design and methodology:
- a randomised, double-blind, controlled trial investigating the effect of long-chain omega-3 fatty acids
- on cognitive ageing and wellbeing in cognitively healthy older adults. Oct 2011
1. PubMed: Omega-3 Cancer__- Omega-3 aids chemotherapy (by reducing inflammation) Jan 2013
- Omega-3 reduce the risk only in patients not taking a statin
- Relationship of dietary intake of omega-3 and omega-6 Fatty acids with risk of prostate cancer development Dec 2012 full text online
- a meta-analysis of prospective studies and reviewthe of literature.High intake of ALA may reduce risk of prostate cancer, while intake of long-chain omega-3 fatty acids does not have a significant effect.
- Omega-3 Fats Help Overcome Multi-Drug Resistant CancerNov 2013
- Nothing about Vitamin D, but interesting anyway - mainly colon cancer, but it might apply to others as well.
1. 1,059+ Clinical Trials of Omega-3- INTERVENTION Clinical trials with Omega-3 **1.059 * as of May 2025
- Bacterial and Fungal Diseases, Behaviors and Mental Disorders , Blood and Lymph Conditions
- Cancers and Other Neoplasms , Digestive System Diseases, Diseases and Abnormalities at or before Birth
- Ear, Nose, and Throat Diseases , Eye Diseases, Gland and Hormone Related Diseases
- Heart and Blood Diseases, Immune System Diseases, Mouth and Tooth Diseases
- Muscle, Bone, and Cartilage Diseases, Nervous System Diseases, Nutritional and Metabolic Diseases
- Occupational Diseases, Parasitic Diseases, Respiratory Tract (Lung and Bronchial) Diseases
- Skin and Connective Tissue Diseases, Substance Related Disorders , Symptoms and General Pathology
- Urinary Tract, Sexual Organs, and Pregnancy Conditions; Viral Diseases; Wounds and Injuries
1. 32+ Intervention trials using BOTH Omega and Vitamin D 1. Increase Omega-3 from cows by feeding them more Omega-3- Supplementing different ratios of short- and medium-chain fatty acids to long-chain fatty acids in dairy cows: Changes of milk fat production and milk fatty acids composition
- Journal of Dairy Science, Feb 2013
- The milk fat percentage and total SMCFA concentration in milk fat tended to increase linearly and the proportion of milk total solids increased linearly with increasing ratios of SMCFA to LCFA in the supplements, whereas milk fat yield was not changed.
1. <a href="http://www.eatwild.com/healthbenefits.htm">Omega-3 from cattle vanish after eating grain in the feedlot</a>
Note:By US definitions Grass fed beed can be grain finished in a feedlot since the definitions are not regulations nor are they checked.
Also: the defintions allow feeding grain for about half of the year - when the grass is not growing
Fatty Acid Analysis of Grass-fed and Grain-fed Beef Tallow Masterjohn Jan 2014
Total PUFA Grain: 3.45% Grass: 1.9%
1. NOTE: PDF of a 2010 study of Cattle and Omega-3 is attached at the bottom of this page 1. 100% grassfed has the best Omega-3 / Omega-6 ratio
author also has a GREAT book on eating far healthier heritage fruits and vegitables Eating on the Wild Side**
http://www.eatwild.com/
1. <a href="/pages/vitamin-d-reduced-so-low-that-victorian-age-diseases-are-returning/">Chart showing decreased Vitamin D for decreased Omega</a>
1. Mortality associated with HUFA (Highly Unsaturated Fatty Acids = Omega-6)
1. Images from the web

1. Now I know why the recent Meta-analysis of Omega-3 did not find any reduction in heart deaths - 2018Previous version of the Cochrane analysis had excluded all trials with fewer than 50 deaths
This review looked at 2100 studies and excluded 90% of them
This review did not mention if they had continued that outrageous exclusion.
details in Orthomolecular Nutrtion
I had wondered how the Cochrane Review could possibly have not found a benefit.
The reading of the paper did not indicate the reason. But now I have found out why.
I wonder how many other Cochrane reviews are similarly biased by excluding studies which find a benefit
Henry Lahore, founder of Vitamin D Life Aug 2018
1. FDA battle against Omega-3 as a way to reduce cardiovascular risk - 2020Are We Finally Reaching Consensus About Fish Oil ? Life Extension Magazine editorial Aug 2020
"On February 26, 1987, the FDA conducted an armed raidagainst Life Extension®
The FDA seized our fish oil and brochures describing fish oil’s potential to reduce cardiovascular risk.
We fought a multi-year legal battle that resulted in the government dismissing all charges against Life Extension®, marking the first time in the FDA’s 88-year history that it has been forced to give up on a criminal prosecution"
1. Fatty acids: facts vs. fiction - 2021 (informative charts)Int J Vitam Nutr Res (2021), 1–21 https://doi.org/10.1024/0300-9831/a000713
📄 Download the PDF from Vitamin D Life
1. Rhonda Patrick podcast: Unconventional effects of omega-3s - March 2022Must be a $5/month member to listen
The cardioprotective effects of omega-3s are pretty well established. But the research on omega-3s has also revealed that they're involved in nearly every aspect of human health, eliciting some unconventional effects that influence neurocognitive, immunological, and respiratory health, and lots more – throughout the lifespan.
In this Aliquot, we share a variety of segments from different interviews covering some of the unconventional effects of omega-3 fatty acids and how to overcome some of the roadblocks to obtaining these effects.
00:00:00 - Omega-3s support the brain, the immune system, and healthy aging
00:03:29 - Omega-3's in breastmilk support brain development
00:05:24 - Omega-3s slow epigenetic aging (Dr. Steve Horvath segment)
00:09:19 - EPA and DHA resolve inflammation
00:10:35 - Omega-3s in phospholipid form are better absorbed (discussion w/ Kevin Rose)
00:18:10 - Sources of phospholipid-bound omega-3s
00:26:23 - Rhonda's omega-3 intake
00:28:15 - Risks of omega-3 supplementation
00:30:28 - Is vegetarian ALA equivalent to marine EPA and DHA?
1. 4 experts agree that Omega-3 can save your life (Algae Omega-3 not blocked by Omega-6?) Oct 2024 1. Dr. Rhonda Patrick Omega-3 Overview - May 2023online {FONT(size="18")} 📄 May 2023 PDF * {FONT}