Liver, Liver Cancer, and Vitamin D

Current therapies in alleviating liver disorders and cancers with a special focus on the potential of vitamin D

Nutrition & Metabolism201815:13, https://doi.org/10.1186/s12986-018-0251-5

Shahida Khan, Ashraf Ali, Sarah Khan, Ahmed Bakillah, Ghazi Damanhouri, Aziz Khan, Ahmed Makki, Ibtehal AlAnsari and Naheed Banu

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Sections

Link of vitamin D and liver complications with other coexisting health disorders

Vitamin D deficiency in chronic liver diseases

Role of vitamin D in non-alcoholic steatohepatitis-

Vitamin D in alcoholic liver disease (ALD)

Vitamin D in viral hepatitis

Possible route of vitamin D in liver cancer

Pivotal role of vitamin D receptors (VDR) and gene expression

Vitamin D analogs

Factors contributing towards vitamin D deficiency, and its supplementation

Other helpful therapies in alleviating liver disorders

Use of nutraceuticals

Role of fiber, vitamins and minerals

Anabolic steroids and growth hormones

Role of omega-3 fatty acids

Role of amino-acids

Enteral and parenteral nutrition

The microbiota connection

Conclusion and future direction