Increased Quality of Life with increased vitamin D

Created April 2014

Vitamin D and health-related quality of life in a community sample of older Canadians.

Qual Life Res. 2014 Apr 24. [Epub ahead of print]

Chao YS1, Ekwaru JP, Ohinmaa A, Griener G, Veugelers PJ.

School of Public Health, University of Alberta, 3-50 University Terrace, 8303 - 112 Street, Edmonton, AB, T6G 2T4, Canada.

Vitamin D levels 36 ng average, and as high as 128 ngWe believe that the participants were encouraged to supplement with vitamin D40 ng increase in vitamin D associated with fewer reported problems* Mobility 40% fewer* Usual activities 30% fewer* Depression and anxiety 30% fewer 1. See also Vitamin D Life* * Quality of Life category listing has items * * Vitamin D associated with 2X better health and less stress, both before and after Breast Cancer – Dec 2014* Vitamin D supplementation improved quality of life – Aug 2015 later publication by many of the same authors

PURPOSE:

To assess how vitamin D status is associated with health-related quality of life (HRQOL) among older residents of Canada.

DESIGN:

We analysed baseline data of 1,493 Canadians aged 50 years and over in Alberta on HRQOL (EQ-5D-5L) and serum 25-hydroxyvitamin D (25(OH)D) as a measure of vitamin D status. We applied multivariable regression methods to examine the association between vitamin D status and each of the five dimensions and the summary index of the EQ-5D-5L.

RESULTS:

Participants with higher serum 25(OH)D levels were significantly less likely to report problems with mobility, usual activities, and depression and anxiety. Specifically, age- and gender-adjusted odds ratios for reporting problems with mobility, usual activities, and depression and anxiety were 0.58 (95 % confidence interval 0.44-0.78), 0.67 (0.50-0.89), and 0.67 (0.51-0.88) per 100 nmol/L increase in 25(OH)D, respectively. No significant associations were observed for problems with self-care and with pain and discomfort. HRQOL scores combining the responses of each of the five dimensions increased significantly with increasing serum 25(OH)D levels.

CONCLUSIONS:

This is the first study to reveal the importance of vitamin D for the five dimensions of HRQOL in a community-based sample. The observed associations of vitamin D and HRQOL call for intervention studies to strengthen the evidence of the potential benefits of vitamin D supplementation for HRQOL among older adults.

PMID: 24760533

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Tags: Canada Quality of Life