Hypothesis: Decreasing Magnesium and increasing CaMg ratio are increasing health problems – 2012 - 2013
2 items by A Rosanoff
Suboptimal magnesium status in the United States: are the health consequences underestimated?
Nutr Rev. 2012 Mar;70(3):153-64. doi: 10.1111/j.1753-4887.2011.00465.x. Epub 2012 Feb 15.
Rosanoff A, Weaver CM, Rude RK.
Center for Magnesium Education & Research, 13-1255 Malama Street, Pahoa, HI 96778, USA. [email protected]
In comparison with calcium, magnesium is an "orphan nutrient" that has been studied considerably less heavily. Low magnesium intakes and blood levels have been associated with type 2 diabetes, metabolic syndrome, elevated C-reactive protein, hypertension, atherosclerotic vascular disease, sudden cardiac death, osteoporosis, migraine headache, asthma, and colon cancer. Almost half (48%) of the US population consumed less than the required amount of magnesium from food in 2005-2006, and the figure was down from 56% in 2001-2002. Surveys conducted over 30 years indicate rising calcium-to-magnesium food-intake ratios among adults and the elderly in the United States, excluding intake from supplements, which favor calcium over magnesium.
The prevalence and incidence of type 2 diabetes in the United States increased sharply between 1994 and 2001
as the ratio of calcium-to-magnesium intake from food rose from <3.0 to >3.0.
Dietary Reference Intakes determined by balance studies may be misleading if subjects have chronic latent magnesium deficiency but are assumed to be healthy. Cellular magnesium deficit, perhaps involving TRPM6/7 channels, elicits calcium-activated inflammatory cascades independent of injury or pathogens. Refining the magnesium requirements and understanding how low magnesium status and rising calcium-to-magnesium ratios influence the incidence of type 2 diabetes, metabolic syndrome, osteoporosis, and other inflammation-related disorders are research priorities.
© 2012 International Life Sciences Institute.
PMID: 22364157
Figure 4: Big increase in Diabetes associated with CaMg ratio > 3
Black bars =Ca/Mg ratio for women
Red lines - % of US who were diabetic
Highlights from PDF
symptoms of DM2 have been associated with intracellular calcium-to-magnesium ratios,96-98
The possibility that some portion of the US population, who are assumed to be healthy and fully magnesium replete, in fact have a chronic latent magnesium deficit complicates the true assessment of this population with regard to magnesium[https://www.Vitamin D Life.com/dl2206 status.
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The Magnesium Hypothesis of Cardiovascular Disease - January 2013
**The Missing Mineral—Magnesium (The Strong Link of Low Nutritional Magnesium and High Calcium-to-Magnesium Ratio in the Genesis of Cardiovascular Disease) A Review of the Peer-Reviewed Science
by A. Rosanoff, PhD, Director of Research & Science Information Outr** each Center for Magnesium Education & Research, Pahoa, HI
PDF is attached at the bottom of this page
Contains a huge number of references and charts about Magnesium and many health problems
See also Vitamin D Life
Hypomagnesemia (low Magnesium) is very prevalent in ICU – 1999
Interactions between Magnesium, Vitamin D, and Calcium – April 2016
Magnesium may be an important way to treat brain trauma wonder if decrease brain trauma if have increased Mg or lower Ca/Mg ratio
Heart problems such as Afib related to little Magnesium, Omega-3, Vitamin D getting to tissues
Correcting magnesium deficiencies may prolong life – Space Station Feb 2012
Magnesium and Vitamin D - similar, different and synergistic
See also web
- Supplemental Magnesium for Prevention of Atrial Fibrillation: Role of Diabetes Mellitus Dec 2012 letter, no text