Child movement disorders reduced in 1 week by Vitamin D injection (China)

Created October 2019

Clinical features of vitamin D deficiency in children: A retrospective analysis.

J Steroid Biochem Mol Biol. 2019 Oct 3:105491. doi: 10.1016/j.jsbmb.2019.105491.

Zhang X1, Liu Z2, Xia L3, Gao J4, Xu F5, Chen H6, Du Y7, Wang W8.

All children with Vitamin D deficiency (< 15ng) were given Calcium then injected with Vitamin D 3 days later Amazingly, the study does not seem to indicate how much Vitamin D nor Calcium was given No mention was made of ongoing vitamin D Injection (expensive) is generally not required * Vitamin D deficiency in China – only 1 in 18 have even 30 ng, fewer if young or female – Feb 2015* 2000 IU vitamin D not enough to get most Chinese to 20 ng level – RCT Feb 2015* Beijing extremely vitamin D deficient even in the fall: 10 ng – April 2013Items in both categories Intervention - non daily and Infant-Child are listed here: {category}Items in both categories Loading Dose and Infant-Child are listed here: {category}Infant-Child category has items and starts with{include}{include}

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Most children improved in 1 week

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Most children had 12 to 28 ng 1 month after injection

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Vitamin D is very important for children's health. Previous studies have shown that vitamin D deficiency leads to a series of diseases in adults. However, pediatricians are mostly aware of rickets caused by vitamin D deficiency in children and poorly aware of other symptoms. This study aimed to retrospectively analyze the different clinical features of vitamin D deficiency to enhance identification by pediatricians, thus minimizing misdiagnosis. In this study, we retrospectively analyzed the clinical features of vitamin D deficiency in 268 children aged 0-14 years from June 2016 to May 2018 in the Third Affiliated Hospital of Zhengzhou University. Serum 25-hydroxy vitamin D [25(OH)D] levels were determined using the chemiluminescence method.

Of the 268 cases,

  • 101 cases showed movement disorder (37.7 %) and

  • 167 nervous system abnormalities (62.3%).

Among all cases, 6 were misdiagnosed as febrile seizures (2.23%), 5 as epilepsy (1.86 %), 2 as Tourette syndrome (0.74%), and 2 as developmental retardation (0.74%).

There were significant differences in patients with clinical characteristics of movement disorder and nervous system abnormalities partly between Pre-and post-vitamin D treatment. This analysis revealed that vitamin D deficiency occurs not only in children but also in adolescents, with diverse clinical features. Therefore, pediatricians should pay more attention to clinical different signs and symptoms, and future studies should be conducted to confirm the mechanisms of these processes.

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Tags: Infant-Child Injection Orient