15 million in the US have 1 or more autoimmune diseases
Mayo Clinic
- 15 million have one or more of 105 autoimmune diseases.
- 65% of patients had one autoimmune disease.
- 24% of patients had two autoimmune diseases.
- etc.
Many of the top 20 autoimmune diseases are treated by high-dose Vitamin D
4.6% of people in the US have an autoimmune disease
Some of the related pages in Vitamin D Life
- Autoimmune
- Gut-Friendly Vitamin D
- Gastrointestinal Health, Vitamin D, and VDR - May 2026
- Video by Dr. Coimbra – 95 % of autoimmune diseases cured with Vitamin D in high doses
- How Vitamin D Cures Autoimmune Disease - Video Dec 2025
- Autoimmune and high-dose vitamin D (Dr. Coimbra) - Dr. Mahtani video and transcript
1) Rheumanoid Arthritis
- Rheumanoid Arthritis: Best VDR activators are Curcumin and Omega-3
- Overview Rheumatoid Arthritis and Vitamin D
- Rheumatoid Arthritis
- Autoimmune Rheumatologic Diseases and High-Dose Vitamin D
2) Psoriasis
3) T1 Diabetes
- Type 1 Diabetes might be prevented by Vitamin D - Dec 2025
- Type 1 diabetes helped with 50,000 IU of Vitamin D every two weeks
- Type 1 Diabetes is prevented and treated by Vitamin D – review of 16 studies
- Type 1 diabetes trial having problems – too many taking Vitamin D or Omega-3
- Type 1 Diabetes association with poor Vitamin D Receptor: 39 studies
4) Graves Disease
5) Thyroiditis (Hashimoto's)
- Hashimoto's thyroiditis: Vitamin D was the most important of 11 variables
- Hashimoto's Thyroiditis and Vitamin D - multiple studies
6) Crohn's Disease
- Crohn's and Vitamin D - many studies
- Crohn's disease associated with 7.6X deactivation of Vitamin D receptor
- Crohn’s disease helped when vitamin D level raised above 30 ng – RCT
- Crohn’s disease associated with vitamin D and latitude – meta-analysis
7) Multiple Sclerosis
- Multiple sclerosis (relapsing-remitting) decreases activation of Vitamin D Receptor by 6.6 X
- Multiple Sclerosis and Vitamin D Receptor Activators: Omega-3, Curcumin, Resveratrol, etc.
- Coimbra Protocol (using Vitamin D) is safe and effective for Multiple Sclerosis and Autoimmune diseases
8) Lupus
- Lupus
- Lupus summary of Vitamin D Life by Perplexity AI - Feb 2026
- Every aspect of Lupus is associated with low Vitamin D
- Lupus patients are 5 X more likely to have low vitamin D – many meta-analyses
- Lupus 3.8 X more likely if a poor Vitamin D Receptor
9) Ulcerative Colitis
- Ulcerative Colitis and Vitamin D - many studies
- Ulcerative Colitis treated 4X better when Vitamin D was added – Meta-Analysis
- Ulcerative Colitis inflammation treated by weekly vitamin D (40,000 IU)
- Turmeric stopped Ulcerative Colitis – RCT
Tumeric activates the Vitamin D Receptor
10) Sjögren’s syndrome
11) Celiac Disease
12) Polymyalgia Rheumatica
- Polymyalgia Rheumatica treated by raising Vitamin D above 40 ng
- Statins associated with 14X increase in Polymyalgia Rheumatica (a new disease)
Many Statins decrease Vitamin D levels
13) Autoimmune Gastritis (often due to H. Pylori)
14) Vitiligo
- Vitiligo (spotty skin) and Vitamin D, UVB - many studies
- Vitiligo associated with low vitamin D (Note: Vit. D and UV has treated it for over a decade) – meta-analysis
- Vitiligo (spotty skin coloring) is 4 X more likely if poor Vitamin D Receptor – meta-analysis
17) Alopecia Areata
- Spot Baldness (Alopecia Areata) associated with low vitamin D – many studies
- Alopecia areata (spot baldness) associated with 8.5 ng lower levels of vitamin D – meta-analysis
18) Juvenile Rheumatoid Arthritis
LIst of 105 autoimmune diseases
Click here to see names of 105 autoimmune diseases
Achalasia, Addison’s Disease, Adult Still’s Disease, Agammaglobulinemia, Alopecia Areata, Amyloidosis, Ankylosing Spondylitis, Anti-GBM/Anti-TBM Nephritis, Antiphospholipid Syndrome, Autoimmune Angioedema, Autoimmune Dysautonomia, Autoimmune Encephalitis, Autoimmune Hepatitis, Autoimmune Inner Ear Disease , Autoimmune Myocarditis, Autoimmune Oophoritis, Autoimmune Orchitis, Autoimmune Pancreatitis, Autoimmune Pulmonary Alveolar Proteinosis , Autoimmune Retinopathy, Autoimmune Urticaria, Axonal & Neuronal Neuropathy , Baló Disease, Behcet’s Disease, Benign Mucosal Pemphigoid , Bullous Pemphigoid, Castleman Disease (CD), Celiac Disease, Chagas Disease, Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Chronic Lyme Disease, Chronic Recurrent Multifocal Osteomyelitis (CRMO), Churg-Strauss Syndrome (CSS) , Cicatricial Pemphigoid, Cogan’s Syndrome, Cold Agglutinin Disease, Complex Regional Pain Syndrome , Congenital Heart Block, Coxsackie Myocarditis, CREST Syndrome, Crohn’s Disease, Dermatitis Herpetiformis, Dermatomyositis, Devic’s Disease, Discoid Lupus, Dressler’s Syndrome, Endometriosis, Eosinophilic Esophagitis , Eosinophilic Fasciitis, Erythema Nodosum, Essential Mixed Cryoglobulinemia, Evans Syndrome, Fibromyalgia, Fibrosing Alveolitis, Giant Cell Arteritis (Temporal Arteritis), Giant Cell Myocarditis, Glomerulonephritis, Goodpasture’s Syndrome, Granulomatosis with Polyangiitis, Graves’ Disease, Guillain-Barre Syndrome, Hashimoto’s Thyroiditis, Hemolytic Anemia, Henoch-Schonlein Purpura (HSP), Herpes Gestationis or, Hidradenitis Suppurativa (HS) (Acne Inversa), IgA Nephropathy, IgG4-Related Sclerosing Disease, Immune Thrombocytopenic Purpura (ITP), Inclusion Body Myositis (IBM), Interstitial Cystitis (IC), Juvenile Arthritis, Juvenile Diabetes (Type 1 Diabetes), Juvenile Myositis (JM), Kawasaki Disease, Lambert-Eaton Syndrome, Lichen Planus, Lichen Sclerosus, Ligneous Conjunctivitis, Linear IgA Disease (LAD), Lupus, Meniere’s Disease, Microscopic Polyangiitis (MPA), Mixed Connective Tissue Disease (MCTD), Mucha-Habermann Disease, Multifocal Motor Neuropathy , Multiple Sclerosis (MS), Myasthenia Gravis, Myelin Oligodendrocyte Glycoprotein Antibody Disorder, Myositis, Narcolepsy, Neonatal Lupus, Neuromyelitis Optica (NMO), Neutropenia, Ocular Cicatricial Pemphigoid, Optic Neuritis, Palindromic Rheumatism (PR), PANDAS , Paraneoplastic Cerebellar Degeneration (PCD), Paroxysmal Nocturnal Hemoglobinuria (PNH), Pars Planitis (Peripheral Uveitis), Parsonage-Turner Syndrome, Pemphigus, Peripheral Neuropathy, Perivenous Encephalomyelitis, Pernicious Anemia (PA), POEMS Syndrome, Polyarteritis Nodosa, Polyglandular Syndromes Type I, II, III, Polymyalgia Rheumatica, Polymyositis, Postmyocardial Infarction Syndrome, Postpericardiotomy Syndrome, Primary Biliary Cholangitis, Primary Sclerosing Cholangitis, Progesterone Dermatitis, Progressive Hemifacial Atrophy (PHA), Parry Romberg Syndrome, Psoriasis, Psoriatic Arthritis, Pulmonary Alveolar Proteinosis (PAP), Pure Red Cell Aplasia (PRCA), Pyoderma Gangrenosum, Raynaud’s Phenomenon, Reactive Arthritis, Relapsing Polychondritis, Restless Legs Syndrome (RLS), Retroperitoneal Fibrosis, Rheumatic Fever, Rheumatoid Arthritis, Sarcoidosis, Schmidt Syndrome or Autoimmune Polyendocrine Syndrome Type II, Scleritis, Scleroderma, Sjögren’s, Stiff Person Syndrome (SPS), Susac’s Syndrome, Sympathetic Ophthalmia (SO), Takayasu’s Arteritis, Temporal Arteritis/Giant Cell Arteritis, Thrombocytopenic Purpura (TTP), Thrombotic Thrombocytopenic Purpura (TTP), Thyroid Eye Disease (TED), Tolosa-Hunt Syndrome (THS), Transverse Myelitis, Type 1 Diabetes, Ulcerative Colitis (UC), Undifferentiated Connective Tissue Disease (UCTD), Uveitis, Vasculitis, Vitiligo, Vogt-Koyanagi-Harada Disease, Warm Autoimmune Hemolytic Anemia