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Vitamin D important papers from 1645 to 2013 – Nov 2013

Historically important and highly-cited vitamin D papers Nov 14, 2013

William B. Grant 1 and Barbara J. Boucher 2
1Sunlight, Nutrition, and Health Research Center (SUNARC)
P.O. Box 641603, San Francisco, CA 94164-1603, USA, www.sunarc.org, wbgrant at infionline.net

2Centre for Diabetes and Metabolic Medicine Bart's and
The London School of Medicine and Dentistry Institute of Cell and Molecular Science
4 Newark Street , London E1 2AT UK , bboucher at doctors.org.uk

This bibliography is based on historically important and/or highly-cited papers on vitamin D.
By historically important we mean papers that were either first on a particular topic or papers that opened the doors to additional studies.
By highly cited, we mean papers with large number of citations for the time of publication based on citations listed at Scholar.Google.com. Scholar.Google.com includes citations from journal papers, reports, and books. The number of citations at Scholar.Google.com is up to a factor of two higher than at the Web of Science, which limits citations to selected journals. The advantages of Scholar.Google.com include that the sources citing the papers of interest are given, that the website has open access, and that if a full text version of the paper is available on the web, a link to it is provided.
(Here is Google Scholar for Vitamin D)

The history of vitamin D has several phases.
The first phase, dating from 1645, was based on understanding the risk factors for rickets.
The effect of vitamin D on calcium and bones remained the primary concern of vitamin D studies through at least 1960.
There were studies of the effect of vitamin D and sunlight on risk of dental caries starting in 1928 [Mellanby et al., 1928],

The second phase starts in 1922 with the identification of vitamin D as a vitamin by McCollum et al. [1922].

The third phase might be considered to start in 1961 with a consideration of the role of vitamin D in the risk of coronary heart disease [Ross and Campbell, 1961].
This appears to be the first consideration of a role for vitamin D for noncalcemic effects although the effect of vitamin A was considered stronger than that of vitamin D.
In 1974, it was proposed that vitamin D affected risk of multiple sclerosis [Goldberg, 1974].
The ultraviolet-B–vitamin D–cancer hypothesis was proposed by the brothers Cedric and Frank Garland in 1980 [Garland and Garland, 1980].
   This paper is considered to have led to over three thousand papers on the topic, which has very strong scientific support now.

Table 1: 18 important milestones regarding the noncalcemic effects of vitamin D

Year Health outcome Reference
1922 Separation of vitamin D from vitamin A McCollum et al., 1922
1928 Dental caries Mellanby et al., 1928
1974 Multiple sclerosis Goldberg, 1974
1980 Colon cancer Garland and Garland, 1980
1980 Insulin control Norman et al., 1980
1980 Crohn’s disease Harries et al., 1985
1986 Skeletal muscle function Boland, 1986
1990 Myocardial infarction Scragg et al., 1990
1993 Vitamin D receptor-retinoid-X receptor-alpha interaction Carlberg et al., 1993
1998 Syndrome ‘X’ Boucher, 1998
1999 Schizophrenia McGrath, 1999
2001 Type 1 diabetes mellitus Hypponen et al., 2001
2001 Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase Zehnder et al., 2001
2003 Non-specific musculoskeletal pain Plotnikoff and Quigley, 2003
2006 Influenza Cannell et al., 2006
2006 Type 2 diabetes mellitus Pittas et al., 2006
2008 Autism Cannell, 2008

191 papers

Note: (xxx GS) means number of citations found at scholar.google.com in October 2013

  • 1645 Whistler D: De morbo puerili Anglorum, quem patrio idiomate indigenae vocant The Rickets. Leiden, ex. Off. W.C. Boxii, 1645.
  • 1660 Glisson F: A treatise of the rickets being a disease common to children. Cambridge, Cambridge University, 1660.
  • 1824 Schütte D: Beobachtungen über den Nutzen des Berger Leberthrans (Oleum jecoris Asseli, von Gadus asellus L.). Arch med Erfahr 1824; 2: 79–92. (7 GS)
  • 1849 Trousseau A, Lasègue C: Du rachitisme et de l ’osteomalacie comparés. Arch Gen Med 1849; 19: 257.
  • 1885 Pommer G: Untersuchungen über Osteomalacie und Rachitis. Leipzig, F.C.W. Vogel, 1885. (113 GS)
  • 1890 Palm TA: The geographical distribution and etiology of rickets. Practitioner 1890; 45: 270–279.
  • 1919 Huldschinsky K. Heilung von Rachitis durch Kunstliche Hohensonne. [Rickets Cured by Ultraviolet Irradiation.] Dtsch Med Wochenschr 1919;45: 712–713. (258 GS) Rickets
  • 1919 Mellanby E, Cantag MD. Experimental investigation on rickets. Lancet 1919;196:407-412. (287 GS)
  • 1921 Mellanby E. Experimental rickets. Medical Research (G.B.), Special Report Series SRS-1921;61:1-78. (121 GS)
  • 1922 McCollum EV, Simmonds N, Becker JE, Shipley PG. Studies on experimental rickets, XXI: an experimental demonstration of the existence of a vitamin which promotes calcium deposition. . 1922;:293–312. (410 GS)
  • 1923 Rollier A. London, England: Henry Frowde and Hodder & Stoughton; 1923.
  • 1923 Steenbock H, Nelson EM. Fat-soluble vitamine, XIII: light in its relation to ophthalmia and growth. . 1923;:355–373. (236 GS)
  • 1924 Steenbock H, Black A. Fat-soluble vitamins: the induction of growth-promoting and calcifying properties in a ration by exposure to ultra-violet light. J Biol Chem. 1924;61:405–422. (267 GS)
  • 1926 Chick H, Roscoe MH. Influence of diet and sunlight upon the amount of vitamin A and vitamin D in the milk afforded by a cow. . 1926;20(3):632-49. (26 GS)
  • 1926 Rosenheim O, Webster TA. The anti-rachitic properties of irradiated sterols. . 1926;20(3):537-44. (40 GS) Rickets
  • 1926 Windaus A . (1926) Sterine und antirachitisches Vitamin. Nachrichten von der Gesellschaft der Wissenschaften zu Göttingen :175-184. (21 GS)
  • 1927 Tisdall FF, Brown A. Seasonal variation of the antirachitic effect of sunshine. Am J Dis Child. 1927;34(5):721-736. (31 GS) Rickets
  • 1928 Mellanby M, Pattison CL. The action of vitamin D in preventing the spread and promoting the arrest of caries in children. Brit Med J 1928;2,:1079-82. (28 GS)
  • 1934 Copping AM. Origin of vitamin D in cod-liver oil: vitamin D content of zooplankton. . 1934;28(4):1516-20. (33 GS)
  • 1934 Murray FG. Pigmentation, sunlight, and nutritional disease. Am Anthropologist. 1934; :438-45. (63 GS)
  • 1935 Bills CE. Physiology of the sterols, including vitamin D. Physiol Rev. 1935;15:1-97. (111 GS)
  • 1936 Brockmann, H. Die Isolierung des antirachitischen Vitamins aus Thunfischleberol. H.-S.Zeit. Physiol. Chem. 241:104-115 (1936). (36 GS)
  • 1936 Stearns G, Jeans PC, Vandecar V. The effect of vitamin D on linear growth in infancy. J Pediatrics. 1936;9:1-10. (47 GS)
  • 1937 Albright F, Butler AM, Bloomburg E. Rickets resistant to vitamin D therapy. Am J Dis Child. 1937;54(3):529-547. (421 GS) Rickets
  • 1946 Bauer JM, Freyberg RH. Vitamin D intoxication with metastatic calcification. JAMA. 1946;130(17):1208-1215 (93 GS)
  • 1947 McCance RA. Osteomalacia with Looser's nodes (Milkman's syndrome) due to a raised resistance to vitamin D acquired about the age of 15 years. . 1947 Jan;16(61):33-46. (194 GS)
  • 1948 Howard JE, Meyer RJ. Intoxication with vitamin D. . 1948 Nov;8(11):895-910. (66 GS)
  • 1950 Harrison HE, Harrison HC. The uptake of radiocalcium by the skeleton: the effect of vitamin D and calcium intake. . 1950 Aug;185(2):857-67. (68 GS)
  • 1952 Carlsson A. Tracer experiments on the effect of vitamin D on the skeletal metabolism of calcium and phosphorus. . 1952 Sep 10;26(2-3):212-20. (127 GS)
  • 1954 Anderson J, Harper C, Dent CE, Philpot GR. Effect of cortisone on calcium metabolism in sarcoidosis with hypercalcaemia; possibly antagonistic actions of cortisone and vitamin D. . 1954 Oct 9;267(6841):720-4. (224 GS)
  • 1956 British Pediatric Association. Hypercalcemia in infants and vitamin D. . 1956;:149. (47 GS)
  • 1956 Forfar JO, Balf CL, Maxwell GM, Tompsett SL. Idiopathic hypercalcaemia of infancy; clinical and metabolic studies with special reference to the aetiological role of vitamin D. . 1956 Jun 23;270(6930):981-8. (75 GS)
  • 1961 Harrison HE, Harrison HC. Intestinal transport of phosphate: action of vitamin D, calcium, and potassium. . 1961 Dec;201:1007-12. (195 GS)
  • 1961 Ross FC, Campbell AH. The effect of vitamin A and vitamin D capsules upon the incidence of coronary heart disease and blood cholesterol. . 1961 Aug 19;48(2):307-11. (12 GS)
  • 1962 DeLuca HF, Engstrom GW, Rasmussen H. The action of vitamin D and parathyroid hormone in vitro on calcium uptake and release by kidney mitochondria. . 1962 Sep 15;48:1604-9. (125 GS)
  • 1963 Rasmussen H, DeLuca H, Arnaud C, Hawker C, Vonstedingk M. The relationship between vitamin D and parathyroid hormone. . 1963 Dec;42:1940-6. (181 GS)
  • 1966 Wasserman RH, Taylor AN. Vitamin d3-induced calcium-binding protein in chick intestinal mucosa. . 1966 May 6;152(3723):791-3. (668 GS)
  • 1968 Blunt JW, DeLuca HF, Schnoes HK. 25-hydroxycholecalciferol. A biologically active metabolite of vitamin D3. . 1968 Oct;7(10):3317-22. (502 GS)
  • 1968 Wasserman RH, Corradino RA, Taylor AN. Vitamin D-dependent calcium-binding protein. Purification and some properties. . 1968 Jul 25;243(14):3978-86. (446 GS)
  • 1969 Ponchon G, Kennan AL, DeLuca HF. "Activation" of vitamin D by the liver. . 1969 Nov;48(11):2032-7. (303 GS)
  • 1970 Dent CE, Richens A, Rowe DJ, Stamp TC. Osteomalacia with long-term anticonvulsant therapy in epilepsy. . 1970 Oct 10;4(5727):69-72. (415 GS)
  • 1970 Fraser DR, Kodicek E. by of a . Nature. 1970;228:764-766. (1110 GS)
  • 1970 Myrtle JF, Haussler MR, Norman AW. Evidence for the biologically active form of cholecalciferol in the intestine. . 1970 Mar 10;245(5):1190-6. (79 GS)
  • 1971 Holick MF, Schnoes HK, DeLuca HF, Suda T, Cousins RJ. Isolation and identification of 1,25-dihydroxycholecalciferol. A metabolite of vitamin D active in intestine. . 1971 Jul 6;10(14):2799-804. (349 GS)
  • 1971 Lawson DE, Fraser DR, Kodicek E, Morris HR, Williams DH. Identification of 1,25-dihydroxycholecalciferol, a new kidney hormone controlling calcium metabolism. . 1971 Mar 26;230(5291):228-30. (403 GS)
  • 1971 Norman AW, Myrtle JF, Midgett RJ, Nowicki HG, Williams V, Popják G. 1,25-dihydroxycholecalciferol: identification of the proposed active form of vitamin D3 in the intestine. . 1971 Jul 2;173(3991):51-4. (166 GS)
  • 1972 Garabedian M, Holick MF, Deluca HF, Boyle IT. Control of 25-hydroxycholecalciferol metabolism by parathyroid glands. . 1972 Jul;69(7):1673-6. (637 GS)
  • 1972 Mawer EB, Backhouse J, Holman CA, Lumb GA, Stanbury SW. The distribution and storage of vitamin D and its metabolites in human tissues. . 1972 Sep;43(3):413-31. (182 GS)
  • 1972 Mawer EB, Backhouse J, Holman CA, Lumb GA, Stanbury SW. The distribution and storage of vitamin D and its metabolites in human tissues. . 1972 Sep;43(3):413-31. (181 GS)
  • 1972 Raisz LG, Trummel CL, Holick MF, DeLuca HF. 1,25-dihydroxycholecalciferol: a potent stimulator of bone resorption in tissue culture. . 1972 Feb 18;175(4023):768-9. (529 GS)
  • 1972 Rasmussen H, Wong M, Bikle D, Goodman DB. Hormonal control of the renal conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. . 1972 Sep;51(9):2502-4. (292 GS)
  • 1973 Fraser D, Kooh SW, Kind HP, Holick MF, Tanaka Y, DeLuca HF. Pathogenesis of hereditary vitamin-D-dependent rickets. An inborn error of vitamin D metabolism involving defective conversion of 25-hydroxyvitamin D to 1 alpha,25-dihydroxyvitamin D. . 1973 Oct 18;289(16):817-22. (316 GS)
  • 1973 Fraser DR, Kodicek E. Regulation of 25-hydroxycholecalciferol-1-hydroxylase activity in kidney by parathyroid hormone. . 1973 Feb 7;241(110):163-6. (410 GS)
  • 1974 Goldberg P. Multiple sclerosis: vitamin D and calcium as environmental determinants of prevalence: (A viewpoint) part 2. biochemical and genetic factors. International J Environ Studies. 1974;6:121-9. (123 GS)
  • 1974 Lumb GA, Stanbury SW. Parathyroid function in human vitamin D deficiency and vitamin D deficiency in primary hyperparathyroidism. . 1974 Jun;56(6):833-9. (104 GS)
  • 1975 Corless D, Boucher BJ, Cohen RD, Beer M, Gupta SP. Vitamin-D status in long-stay geriatric patients. . 1975 Jun 28;1(7922):1404-6. (131 GS)
  • 1975 Preece MA, TomlinsonS, Ribot CA, Pietrek J, Korn HT, Davies DM, Ford JA, Dunnigan MG, O'Riordan JL. Studies of vitamin D deficiency in man. . 1975 Oct;44(176):575-89. (187 GS)
  • 1976 DeLuca HF, Schnoes HK. Metabolism and mechanism of action of vitamin D. . 1976;45:631-66. (549 GS)
  • 1976 Eastwood JB, Stamp TC, Harris E, de Wardener HE. Vitamin-D deficiency in the osteomalacia of chronic renal failure. . 1976 Dec 4;2(7997):1209-11. (102 GS)
  • 1976 Haddad JG Jr, Walgate J. 25-Hydroxyvitamin D transport in human plasma. Isolation and partial characterization of calcifidiol-binding protein. . 1976 Aug 25;251(16):4803-9. (198 GS)
  • 1977 Haussler MR, McCain TA. Basic and clinical concepts related to vitamin D metabolism and action (first of two parts). . 1977 Nov 3;297(18):974-83. (547 GS)
  • 1978 Brooks MH, Bell NH, Love L, Stern PH, Orfei E, Queener SF, Hamstra AJ, DeLuca HF. Vitamin-D-dependent rickets type II. Resistance of target organs to 1,25-dihydroxyvitamin D. . 1978 May 4;298(18):996-9. (237 GS)
  • 1979 DeLuca HF. The vitamin D system in the regulation of calcium and phosphorus metabolism. . 1979 Jun;37(6):161-93. (237 GS)
  • 1979 Gallagher JC, Riggs BL, Eisman J, Hamstra A, Arnaud SB, DeLuca HF. Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients: effect of age and dietary calcium. . 1979 Sep;64(3):729-36. (693 GS)
  • 1979 Norman A. Vitamin D: The Calcium Homeostatic Steroid Hormone. Academic Press. 1979 (336 GS)
  • 1980 Garland CF, Garland FC. Do sunlight and vitamin D reduce the likelihood of colon cancer? Int J Epidemiol. 1980 Sep;9(3):227-31. (626 GS)
  • 1980 Holick MF, MacLaughlin JA, Clark MB, Holick SA, Potts JT Jr, Anderson RR, Blank IH, Parrish JA, Elias P. Photosynthesis of previtamin D3 in human skin and the physiologic consequences. . 1980 Oct 10;210(4466):203-5. (440 GS)
  • 1980 Norman AW, Frankel JB, Heldt AM, Grodsky GM. Vitamin D deficiency inhibits pancreatic secretion of insulin. . 1980 Aug 15;209(4458):823-5. (392 GS)
  • 1981 Abe E, Miyaura C, Sakagami H, Takeda M, Konno K, Yamazaki T, Yoshiki S, Suda T. Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3. . 1981 Aug;78(8):4990-4. (1034 GS)
  • 1981 Bouillon R, Van Assche FA, Van Baelen H, Heyns W, De Moor P. Influence of the vitamin D-binding protein on the serum concentration of 1,25-dihydroxyvitamin D3. Significance of the free 1,25-dihydroxyvitamin D3 concentration. . 1981 Mar;67(3):589-96. (321 GS)
  • 1981 Jande SS, Maler L, Lawson DE. Immunohistochemical mapping of vitamin D-dependent calcium-binding protein in brain. . 1981 Dec 24;294(5843):765-7. (363 GS)
  • 1981 Marya RK, Rathee S, Lata V, Mudgil S. Effects of vitamin D supplementation in pregnancy. . 1981;12(3):155-61. (99 GS)
  • 1982 Clemens TL, Adams JS, Henderson SL, Holick MF. Increased skin pigment reduces the capacity of skin to synthesise vitamin D3. . 1982 Jan 9;1(8263):74-6. (725 GS)
  • 1982 Norman AW, Roth J, Orci L. The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins). . 1982 Fall;3(4):331-66. (628 GS)
  • 1985 Garland C, Shekelle RB, Barrett-Connor E, Criqui MH, Rossof AH, Paul O. Dietary vitamin D and calcium and risk of colorectal cancer: a 19-year prospective study in men. Lancet. 1985 Feb 9;1(8424):307-9. (687 GS)
  • 1985 Harries AD, Brown R, Heatley RV, Williams LA, Woodhead S, Rhodes J. Vitamin D status in Crohn's disease: association with nutrition and disease activity. . 1985 Nov;26(11):1197-203. (95 GS)
  • 1985 MacLaughlin J, Holick MF. Aging decreases the capacity of human skin to produce vitamin D3. . 1985 Oct;76(4):1536-8. (782 GS)
  • 1986 Boland R. Role of vitamin D in skeletal muscle function. . 1986 Nov;7(4):434-48. (317 GS)
  • 1986 Gedik O, Akalin S. Effects of vitamin D deficiency and repletion on insulin and glucagon secretion in man. . 1986 Mar;29(3):142-5. (155 GS)
  • 1986 Goldberg P, Fleming MC, Picard EH. Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. . 1986 Oct;21(2):193-200. (209 GS)
  • 1986 MacLaughlin J, Holick MF. Aging decreases the capacity of human skin to produce vitamin D3. . 1985 Oct;76(4):1536-8. (781 GS)
  • 1987 Matsuoka LY, Ide L, Wortsman J, MacLaughlin JA, Holick MF. Sunscreens suppress cutaneous vitamin D3 synthesis. . 1987 Jun;64(6):1165-8. (441 GS)
  • 1988 Webb AR, Kline L, Holick MF. Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin. . 1988 Aug;67(2):373-8. (1080 GS)
  • 1989 Garland CF, Comstock GW, Garland FC, Helsing KJ, Shaw EK, Gorham ED. Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. . 1989 Nov 18;2(8673):1176-8. (547 GS)
  • 1989 Reichel H, Koeffler HP, Norman AW. The role of the vitamin D endocrine system in health and disease. . 1989 Apr 13;320(15):980-91. (962 GS)
  • 1990 Scragg R, Jackson R, Holdaway IM, Lim T, Beaglehole R. Myocardial infarction is inversely associated with plasma 25-hydroxyvitamin D3 levels: a community-based study. . 1990 Sep;19(3):559-63. (294 GS)
  • 1992 Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ. Vitamin D3 and calcium to prevent hip fractures in the elderly women. . 1992 Dec 3;327(23):1637-42. (2801 GS)
  • 1992 Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM. Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling. . 1992 Jan 30;355(6359):446-9. (1223 GS)
  • 1993 Carlberg C, Bendik I, Wyss A, Meier E, Sturzenbecker LJ, Grippo JF, Hunziker W. Two nuclear signalling pathways for vitamin D. . 1993 Feb 18;361(6413):657-60. (432 GS)
  • 1995 Bouillon R, Okamura WH, Norman AW. Structure-function relationships in the vitamin D endocrine system. . 1995 Apr;16(2):200-57. (1175 GS)
  • 1995 Holick MF. Environmental factors that influence the cutaneous production of vitamin D. . 1995 Mar;61(3 Suppl):638S-645S. (471 GS)
  • 1995 van der Wielen RP, Löwik MR, van den Berg H, de Groot LC, Haller J, Moreiras O, van Staveren WA. Serum vitamin D concentrations among elderly people in Europe. . 1995 Jul 22;346(8969):207-10. (569 GS)
  • 1996 Lips P, Graafmans WC, Ooms ME, Bezemer PD, Bouter LM. Vitamin D supplementation and fracture incidence in elderly persons. A randomized, placebo-controlled clinical trial. . 1996 Feb 15;124(4):400-6. (664 GS)
  • 1997 Chapuy MC, Preziosi P, Maamer M, Arnaud S, Galan P, Hercberg S, Meunier PJ. Prevalence of vitamin D insufficiency in an adult normal population. . 1997;7(5):439-43. (1171 GS)
  • 1997 Cross HS, Peterlik M, Reddy GS, Schuster I. Vitamin D metabolism in human colon adenocarcinoma-derived Caco-2 cells: expression of 25-hydroxyvitamin D3-1alpha-hydroxylase activity and regulation of side-chain metabolism. . 1997 May;62(1):21-8. (120 GS)
  • 1997 Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. . 1997 Sep 4;337(10):670-6. (2052 GS)
  • 1997 Watson KE, Abrolat ML, Malone LL, Hoeg JM, Doherty T, Detrano R, Demer LL. Active serum vitamin D levels are inversely correlated with coronary calcification. . 1997 Sep 16;96(6):1755-60. (377 GS)
  • 1998 Awumey EM, Mitra DA, Hollis BW, Kumar R, Bell NH. Vitamin D metabolism is altered in Asian Indians in the southern United States: a clinical research center study. . 1998 Jan;83(1):169-73. (146 GS)
  • 1998 Boucher BJ. Inadequate vitamin D status: does it contribute to the disorders comprising syndrome 'X'? . 1998 Apr;79(4):315-27. (221 GS)
  • 1998 Haussler MR, Whitfield GK, Haussler CA, Hsieh JC, Thompson PD, Selznick SH, Dominguez CE, Jurutka PW. The nuclear vitamin D receptor: biological and molecular regulatory properties revealed. . 1998 Mar;13(3):325-49. (945 GS)
  • 1998 Malabanan A, Veronikis IE, Holick MF. Redefining vitamin D insufficiency. . 1998 Mar 14;351(9105):805-6. (896 GS)
  • 1999 Bellamy R, Ruwende C, Corrah T, McAdam KP, Thursz M, Whittle HC, Hill AV. Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene. . 1999 Mar;179(3):721-4. (398 GS)
  • 1999 McGrath J. Hypothesis: is low prenatal vitamin D a risk-modifying factor for schizophrenia? . 1999 Dec 21;40(3):173-7. (233 GS)
  • 1999 Nykjaer A, Dragun D, Walther D, Vorum H, Jacobsen C, Herz J, Melsen F, Christensen EI, Willnow TE. An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3. . 1999 Feb 19;96(4):507-15. (579 GS)
  • 1999 Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. . 1999 May;69(5):842-56. (1139 GS)
  • 2000 Jablonski NG, Chaplin G. The evolution of human skin coloration. . 2000 Jul;39(1):57-106. (652 GS)
  • 2000 Wilkinson RJ, Llewelyn M, Toossi Z, Patel P, Pasvol G, Lalvani A, Wright D, Latif M, Davidson RN. Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study. . 2000 Feb 19;355(9204):618-21. (541 GS)
  • 2000 Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. . 2000 Sep;72(3):690-3. (1195 GS)
  • 2001 Hyppönen E, Läärä E, Reunanen A, Järvelin MR, Virtanen SM. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. . 2001 Nov 3;358(9292):1500-3. (1361 GS)
  • 2001 Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. . 2001 Aug;22(4):477-501. (1190 GS)
  • 2001 Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C. Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. . 2001 Apr;86(4):1633-7. (488 GS)
  • 2001 Vieth R, Chan PC, MacFarlane GD. Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect level. . 2001 Feb;73(2):288-94. (510 GS)
  • 2001 Zehnder D, Bland R, Williams MC, McNinch RW, Howie AJ, Stewart PM, Hewison M. Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase. . 2001 Feb;86(2):888-94. (554 GS)
  • 2001 Zehnder D, Bland R, Williams MC, McNinch RW, Howie AJ, Stewart PM, Hewison M. Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase. . 2001 Feb;86(2):888-94. (549 GS)
  • 2002 Grant WB. An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation. Cancer. 2002 Mar 15;94(6):1867-75. (669 GS)
  • 2002 Makishima M, Lu TT, Xie W, Whitfield GK, Domoto H, Evans RM, Haussler MR, Mangelsdorf DJ. Vitamin D receptor as an intestinal bile acid sensor. . 2002 May 17;296(5571):1313-6. (569 GS)
  • 2002 Nesby-O'Dell S, Scanlon KS, Cogswell ME, Gillespie C, Hollis BW, Looker AC, Allen C, Doughertly C, Gunter EW, Bowman BA. Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994. . 2002 Jul;76(1):187-92. (756 GS)
  • 2002 Tangpricha V, Pearce EN, Chen TC, Holick MF. Vitamin D insufficiency among free-living healthy young adults. . 2002 Jun 1;112(8):659-62. (473 GS)
  • 2003 Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. . 2003 Jan;77(1):204-10. (884 GS)
  • 2003 Heaney RP, Dowell MS, Hale CA, Bendich A. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. . 2003 Apr;22(2):142-6. (694 GS)
  • 2003 Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. . 2003 Dec;78(12):1463-70. (450 GS)
  • 2003 Trivedi DP, Doll R, Khaw KT. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. . 2003 Mar 1;326(7387):469. (923 GS)
  • 2003 Visser M, Deeg DJ, Lips P; Longitudinal Aging Study Amsterdam. Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. . 2003 Dec;88(12):5766-72. (418 GS)
  • 2003 Zittermann A. Vitamin D in preventive medicine: are we ignoring the evidence? . 2003 May;89(5):552-72. (668 GS)
  • 2004 Armas LA, Hollis BW, Heaney RP. Vitamin D2 is much less effective than vitamin D3 in humans. . 2004 Nov;89(11):5387-91. (698 GS)
  • 2004 Chiu KC, Chu A, Go VL, Saad MF. Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. . 2004 May;79(5):820-5. (938 GS)
  • 2004 DeLuca HF. Overview of general physiologic features and functions of vitamin D. . 2004 Dec;80(6 Suppl):1689S-96S. (793 GS)
  • 2004 Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. . 2004 Dec;80(6 Suppl):1678S-88S. (1316 GS)
  • 2004 Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. . 2004 Mar;79(3):362-71. (1113 GS)
  • 2004 Munger KL, Zhang SM, O'Reilly E, Hernán MA, Olek MJ, Willett WC, Ascherio A. Vitamin D intake and incidence of multiple sclerosis. . 2004 Jan 13;62(1):60-5. (686 GS)
  • 2004 Shimada T, Hasegawa H, Yamazaki Y, Muto T, Hino R, Takeuchi Y, Fujita T, Nakahara K, Fukumoto S, Yamashita T. FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. . 2004 Mar;19(3):429-35. (595 GS)
  • 2004 Shimada T, Kakitani M, Yamazaki Y, Hasegawa H, Takeuchi Y, Fujita T, Fukumoto S, Tomizuka K, Yamashita T. Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. . 2004 Feb;113(4):561-8. (667 GS)
  • 2005 Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. . 2005 May 11;293(18):2257-64. (1158 GS)
  • 2005 Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R. Estimates of optimal vitamin D status. . 2005 Jul;16(7):713-6. (1270 GS)
  • 2005 Eyles DW, Smith S, Kinobe R, Hewison M, McGrath JJ. Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain. . 2005 Jan;29(1):21-30. (339 GS)
  • 2005 Grant AM, Avenell A, Campbell MK, McDonald AM, MacLennan GS, McPherson GC, Anderson FH, Cooper C, Francis RM, Donaldson C, Gillespie WJ, Robinson CM, Torgerson DJ, Wallace WA; RECORD Trial Group. Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial. . 2005 May 7-13;365(9471):1621-8. (677 GS)
  • 2005 Holick MF, Siris ES, Binkley N, Beard MK, Khan A, Katzer JT, Petruschke RA, Chen E, de Papp AE. Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy. . 2005 Jun;90(6):3215-24. (600 GS)
  • 2005 Hollis BW. Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin D. . 2005 Feb;135(2):317-22. (756 GS)
  • 2005 Teng M, Wolf M, Ofsthun MN, Lazarus JM, Hernán MA, Camargo CA Jr, Thadhani R. Activated injectable vitamin D and hemodialysis survival: a historical cohort study. . 2005 Apr;16(4):1115-25. (614 GS)
  • 2006 Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY, Wong JB. Effect of Vitamin D on falls: a meta-analysis. . 2004 Apr 28;291(16):1999-2006. (1084 GS)
  • 2006 Cannell JJ, Vieth R, Umhau JC, Holick MF, Grant WB, Madronich S, Garland CF, Giovannucci E. Epidemic influenza and vitamin D. . 2006 Dec;134(6):1129-40. (512 GS)
  • 2006 Garland CF, Garland FC, Gorham ED, Lipkin M, Newmark H, Mohr SB, Holick MF. The role of vitamin D in cancer prevention. Am J Public Health. 2006 Feb;96(2):252-61. (644 GS)
  • 2006 Giovannucci E, Liu Y, Rimm EB, Hollis BW, Fuchs CS. Stampfer MJ, Willett WH. Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. JNCI 2006; 98:451-9. (697 GS)
  • 2006 Holick MF. High prevalence of vitamin D inadequacy and implications for health. . 2006 Mar;81(3):353-73. (996 GS)
  • 2006 Lips P. Vitamin D physiology. . 2006 Sep;92(1):4-8. (477 GS)
  • 2006 Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zugel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science. 2006 Mar 24;311(5768):1770-3. (1593 GS)
  • 2006 Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. . 2006 Dec 20;296(23):2832-8. (901 GS)
  • 2006 Pittas AG, Dawson-Hughes B, Li T, Van Dam RM, Willett WC, Manson JE, Hu FB. Vitamin D and calcium intake in relation to type 2 diabetes in women. . 2006 Mar;29(3):650-6. (459 GS)
  • 2006 Schleithoff SS, Zittermann A, Tenderich G, Berthold HK, Stehle P, Koerfer R. Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial. . 2006 Apr;83(4):754-9. (454 GS)
  • 2007 Autier P, Gandini S. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. . 2007 Sep 10;167(16):1730-7. (883 GS)
  • 2007 Camargo CA Jr, Rifas-Shiman SL, Litonjua AA, Rich-Edwards JW, Weiss ST, Gold DR, Kleinman K, Gillman MW. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. . 2007 Mar;85(3):788-95. (373 GS)
  • 2007 Holick MF. Vitamin D deficiency. . 2007 Jul 19;357(3):266-81. (4981 GS)
  • 2007 Lappe JM, Travers-Gustafson D, Davies KM, Recker RR, Heaney RP. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr. 2007 Jun;85(6):1586-91. (978 GS)
  • 2007 Levin A, Bakris GL, Molitch M, Smulders M, Tian J, Williams LA, Andress DL. Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease. . 2007 Jan;71(1):31-8. (659 GS)
  • 2007 Pittas AG, Lau J, Hu FB, Dawson-Hughes B. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. . 2007 Jun;92(6):2017-29. (796 GS)
  • 2007 Vieth R, Bischoff-Ferrari H, Boucher BJ, Dawson-Hughes B, Garland CF, Heaney RP, Holick MF, Hollis BW, Lamberg-Allardt C, McGrath JJ, Norman AW, Scragg R, Whiting SJ, Willett WC, Zittermann A. The urgent need to recommend an intake of vitamin D that is effective. . 2007 Mar;85(3):649-50. (556 GS)
  • 2007 Wicherts IS, van Schoor NM, Boeke AJ, Visser M, Deeg DJ, Smit J, Knol DL, Lips P. Vitamin D status predicts physical performance and its decline in older persons. . 2007 Jun;92(6):2058-65. (243 GS)
  • 2007 Wolf M, Shah A, Gutierrez O, Ankers E, Monroy M, Tamez H, Steele D, Chang Y, Camargo CA Jr, Tonelli M, Thadhani R. Vitamin D levels and early mortality among incident hemodialysis patients. . 2007 Oct;72(8):1004-13. (499 GS)
  • 2008 Adams JS, Hewison M. Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. . 2008 Feb;4(2):80-90. (271 GS)
  • 2008 Bouillon R, Carmeliet G, Verlinden L, van Etten E, Verstuyf A, Luderer HF, Lieben L, Mathieu C, Demay M. Vitamin D and human health: lessons from vitamin D receptor null mice. . 2008 Oct;29(6):726-76. (507 GS)
  • 2008 Cannell JJ. Autism and vitamin D. . 2008;70(4):750-9. (139 GS)
  • 2008 Dobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz W. Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality. . 2008 Jun 23;168(12):1340-9. (706 GS)
  • 2008 Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. . 2008 Jun 9;168(11):1174-80. (717 GS)
  • 2008 Holick MF, Biancuzzo RM, Chen TC, Klein EK, Young A, Bibuld D, Reitz R, Salameh W, Ameri A, Tannenbaum AD. Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D. . 2008 Mar;93(3):677-81. (469 GS)
  • 2008 Melamed ML, Michos ED, Post W, Astor B. 25-hydroxyvitamin D levels and the risk of mortality in the general population. . 2008 Aug 11;168(15):1629-37. (687 GS)
  • 2008 Wagner CL, Greer FR; American Academy of Pediatrics Section on Breastfeeding; American Academy of Pediatrics Committee on Nutrition. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. . 2008 Nov;122(5):1142-52. (540 GS)
  • 2008 Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, Benjamin EJ, D'Agostino RB, Wolf M, Vasan RS. Vitamin D deficiency and risk of cardiovascular disease. . 2008 Jan 29;117(4):503-11. (1185 GS)
  • 2009 Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, Orav JE, Stuck AE, Theiler R, Wong JB, Egli A, Kiel DP, Henschkowski J. Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. . 2009 Oct 1;339:b3692. (587 GS)
  • 2009 Bischoff-Ferrari HA, Willett WC, Wong JB, Stuck AE, Staehelin HB, Orav EJ, Thoma A, Kiel DP, Henschkowski J. Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. . 2009 Mar 23;169(6):551-61. (490 GS)
  • 2009 Ginde AA, Liu MC, Camargo CA Jr. Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004. . 2009 Mar 23;169(6):626-32. (531 GS)
  • 2009 Mithal A, Wahl DA, Bonjour JP, Burckhardt P, Dawson-Hughes B, Eisman JA, El-Hajj Fuleihan G, Josse RG, Lips P, Morales-Torres J; IOF Committee of Scientific Advisors (CSA) Nutrition Working Group. Global vitamin D status and determinants of hypovitaminosis D. . 2009 Nov;20(11):1807-20. (366 GS)
  • 2010 Adams JS, Hewison M. Update in vitamin D. . 2010 Feb;95(2):471-8. (345 GS)
  • 2010 Bolland MJ, Avenell A, Baron JA, Grey A, MacLennan GS, Gamble GD, Reid IR. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. . 2010 Jul 29;341:c3691. (486 GS)
  • 2010 Dawson-Hughes B, Mithal A, Bonjour JP, Boonen S, Burckhardt P, Fuleihan GE, Josse RG, Lips P, Morales-Torres J, Yoshimura N. IOF position statement: vitamin D recommendations for older adults. . 2010 Jul;21(7):1151-4. (240 GS)
  • 2010 Sanders KM, Stuart AL, Williamson EJ, Simpson JA, Kotowicz MA, Young D, Nicholson GC. Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial. . 2010 May 12;303(18):1815-22. (393 GS)
  • 2010 Souberbielle JC, Body JJ, Lappe JM, Plebani M, Shoenfeld Y, Wang TJ, Bischoff-Ferrari HA, Cavalier E, Ebeling PR, Fardellone P, Gandini S, Gruson D, Guérin AP, Heickendorff L, Hollis BW, Ish-Shalom S, Jean G, von Landenberg P, Largura A, Olsson T, Pierrot-Deseilligny C, Pilz S, Tincani A, Valcour A, Zittermann A. Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice. . 2010 Sep;9(11):709-15. (237 GS)
  • 2010 Urashima M, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H. Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. . 2010 May;91(5):1255-60. (324 GS)
  • 2011 Bolland MJ, Grey A, Avenell A, Gamble GD, Reid IR. Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis. . 2011 Apr 19;342:d2040. (300 GS)
  • 2011 Heaney RP, Holick MF. Why the IOM recommendations for vitamin D are deficient.
  • 2011 Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, Murad MH, Weaver CM. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab, 2011 Jul;96(7):1911-30. (930 GS)
  • 2011 Hollis BW, Johnson D, Hulsey TC, Ebeling M, Wagner CL. Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness. . 2011 Oct;26(10):2341-57. (159 GS)
  • 2011 Martineau AR, Timms PM, Bothamley GH, Hanifa Y, Islam K, Claxton AP, Packe GE, Moore-Gillon JC, Darmalingam M, Davidson RN, Milburn HJ, Baker LV, Barker RD, Woodward NJ, Venton TR, Barnes KE, Mullett CJ, Coussens AK, Rutterford CM, Mein CA, Davies GR, Wilkinson RJ, Nikolayevskyy V, Drobniewski FA, Eldridge SM, Griffiths CJ. High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. . 2011 Jan 15;377(9761):242-50. (201 GS)
  • 2011 Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SA. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know.
  • 2012 Bischoff-Ferrari HA, Willett WC, Orav EJ, Lips P, Meunier PJ, Lyons RA, Flicker L, Wark J, Jackson RD, Cauley JA, Meyer HE, Pfeifer M, Sanders KM, Stähelin HB, Theiler R, Dawson-Hughes B. A pooled analysis of vitamin D dose requirements for fracture prevention. . 2012 Jul 5;367(1):40-9. (115 GS)
  • 2012 Carlberg C, Seuter S, Heikkinen S. The first genome-wide view of vitamin D receptor locations and their mechanistic implications. . 2012 Jan;32(1):271-82. (24 GS)
    In vitaminDWiki Vitamin D Receptor locations – Dec 2012
  • 2012 Farrell CJ, Martin S, McWhinney B, Straub I, Williams P, Herrmann M. State-of-the-art vitamin D assays: a comparison of automated immunoassays with liquid chromatography-tandem mass spectrometry methods. . 2012 Mar;58(3):531-42. (61 GS)
  • 2012 Grant WB. Ecological studies of the UVB-vitamin D-cancer hypothesis. . 2012 Jan;32(1):223-36. (58 GS)
  • 2012 Hewison M. An update on vitamin D and human immunity. . 2012 Mar;76(3):315-25. (56 GS)
  • 2012 Hewison M. Vitamin D and immune function: autocrine, paracrine or endocrine? . 2012 Apr;243:92-102. (16 GS)
  • 2012 Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, Murad MH, Weaver CM. Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited. . 2012;97(4):1153-8. (72 GS)
  • 2012 Manson JE, Bassuk SS, Lee IM, Cook NR, Albert MA, Gordon D, Zaharris E, Macfadyen JG, Danielson E, Lin J, Zhang SM, Buring JE. The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease. . 2012 Jan;33(1):159-71. (78 GS)
  • 2012 Rejnmark L, Avenell A, Masud T, Anderson F, Meyer HE, Sanders KM, Salovaara K, Cooper C, Smith HE, Jacobs ET, Torgerson D, Jackson RD, Manson JE, Brixen K, Mosekilde L, Robbins JA, Francis RM, Abrahamsen B. Vitamin D with calcium reduces mortality: Patient level pooled analysis of 70,528 patients from eight major vitamin D trials. J Clin Endocrinol Metab. 2012 Aug;97(8):2670-81. (49 GS)
  • 2012 Rosen CJ, Adams JS, Bikle DD, Black DM, Demay MB, Manson JE, Murad MH, Kovacs CS. The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. . 2012 Jun;33(3):456-92. (62 GS)
  • 2012 Thadhani R, Appelbaum E, Pritchett Y, Chang Y, Wenger J, Tamez H, Bhan I, Agarwal R, Zoccali C, Wanner C, Lloyd-Jones D, Cannata J, Thompson BT, Andress D, Zhang W, Packham D, Singh B, Zehnder D, Shah A, Pachika A, Manning WJ, Solomon SD. Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial. . 2012 Feb 15;307(7):674-84. (97)
  • 2012 Tripkovic L, Lambert H, Hart K, Smith CP, Bucca G, Penson S, Chope G, Hyppönen E, Berry J, Vieth R, Lanham-New S. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. . 2012 Jun;95(6):1357-64. (54 GS)
  • 2012 Vacek JL, Vanga SR, Good M, Lai SM, Lakkireddy D, Howard PA. Vitamin D deficiency and supplementation and relation to cardiovascular health. . 2012 Feb 1;109(3):359-63. (69 GS)
  • 2012 Zittermann A, Iodice S, Pilz S, Grant WB, Bagnardi V, Gandini S. Vitamin D deficiency and mortality risk in the general population: A meta-analysis of prospective cohort studies.
  • 2013 Annweiler C, Llewellyn DJ, Beauchet O. Low serum vitamin D concentrations in Alzheimer's disease: a systematic review and meta-analysis. . 2013;33(3):659-74. (21 GS)
  • 2013 Girgis CM, Clifton-Bligh RJ, Hamrick MW, Holick MF, Gunton JE. The roles of vitamin D in skeletal muscle: form, function, and metabolism. . 2013 Feb;34(1):33-83. (26 GS)
  • 2013 Hollis BW, Wagner CL. The role of the parent compound vitamin D with respect to metabolism and function: Why clinical dose intervals can affect clinical outcomes. . 2013 Oct 8. [Epub ahead of print]
  • 2013 Hossein-Nezhad A, Holick MF. Vitamin D for health: A global perspective. . 2013 July;88(7):720-55. (9 GS)

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Vitamin D important papers from 1645 to 2013 – Nov 2013        
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