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Vitamin D and Allergic Disease: Sunlight at the End of the Tunnel – Dec 2011

Nutrients 2012, 4(1), 13-28; doi:10.3390/nu4010013
Review
Anderson P. Jones, Meri K. Tulic, Kristina Rueter and Susan L. Prescott sprescott at meddent.uwa.edu.au
School of Paediatrics and Child health, University of Western Australia, Perth, Western Australia 6008, Australia
Received: 11 November 2011; in revised form: 2 December 2011 / Accepted: 20 December 2011 / Published: 28 December 2011
(This article belongs to the Special Issue Nutritional Immunology)
Download PDF Full-Text 198 KB, uploaded 28 December 2011 13:45 CET

Abstract: A role for vitamin D in the regulation of immune function was first proposed after the identification of Vitamin D Receptors in lymphocytes. It has since been recognized that the active form of vitamin D, 1?,25(OH)2D3, has direct affects on naïve and activated helper T cells, regulatory T cells, activated B cells and dendritic cells. There is a growing body of literature linking vitamin D (serum 25(OH)D, oral intake and surrogate indicators such as latitude) to various immune-related conditions, including allergy, although the nature of this relationship is still unclear. This review explores the findings of epidemiological, clinical and laboratory research, and the potential role of vitamin D in promoting the inappropriate immune responses which underpin the rise in a broad range of immune diseases.

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See also Vitamin D Life

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1309 Vitamin D and Allergic Disease - Dec 2011.pdf PDF admin 05 May, 2012 08:46 198.43 Kb 729
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