Vitamin D status and Type 1 diabetes in children: evaluation according to latitude and skin colour.
Minerva Pediatr. 2015 Jan 21. [Epub ahead of print]
Cadario F1, Prodam F, Savastio S, Monzani A, Balafrej A, Bellomo G, Bona G.
1 Division of Pediatrics, Department of Health Sciences, Università del Piemonte Orientale "AmedeoAvogadro", Novara, Italy - francesco.cadario at maggioreosp.novara.it.
Moroccan children
In Piedmont (latitude 45 degrees North)
T1D = 12 ng, no diabetes = 17 ng
In Morroco (latitude 32 degrees North)
no difference in vitamin D levels with/without diabetes
See also Vitamin D Life
T1 diabetes OR type1 diabetes in title 24 as of Jan 2015
Pages listed in BOTH the categories Diabetes and Dark Skin
- Children in India – 1 in 7 extremely low Vitamin D, 1 in 10 prediabetic – Sept 2019
- Blacks die more often than whites of many diseases (they have less vitamin D) – 2012
- Diabetic blacks – 80 percent had low vitamin D (less than 20 ng) a decade before – Sept 2017
- Diabetes is associated with low vitamin D in various races, but not blacks – Sept 2015
- Diabetes (Type 1) 14X more likely in dark skin children with low levels of vitamin D – May 2015
- Obese diabetics with dark skins not benefit from 6,000 IU of vitamin D daily (no surprise) – RCT March 2015
- Diabetic glycation control is inversely related to Vitamin D in India – Feb 2015
- Type I diabetes in dark skin children associated with low vitamin D if far from equator – Jan 2015
- Dr. Holick video on vitamin D - March 2013
- African-Americans at high risk of obesity and diabetes - 2011
- Type 1 Diabetes associated with low vitamin D, especially in dark skinned youths – Dec 2012
- Hyperglycemia in black veterans is associated with low vitamin D – Nov 2012
- Diabetics with darker skin were more vitamin D deficient – May 2012
- Low vitamin D associated with obesity-related diseases for ethnic minorities – Sept 2011
- 97 percent of Native American children have less than 30 ng of vitamin D – Oct 2011
- Diabetic neuropathy and low vitamin D, especially in blacks - July 2011
- Studies linked low vitamin D and dark skin to Obesity, Diabetes, and heart – June 2011
- Not yet certain that vitamin D reduces cardiovascular and diabetes in blacks – Mar 2011
- Diabetes Statistics including more diabetes with darker skin – 2007
- Insulin resistance correlated with low vitamin D levels in Arab Americans – June 2010
- Insulin sensitivity associated with Vit D in A-A April 2010
- Vitamin D deficiency and insulin insensitivity in African Americans - 2010
AIM:
We aim to investigate vitamin D (25OHD) levels in children with or without type 1 diabetes (T1D) according to latitude and skin colour.
METHODS:
We compared 25OHD levels in children with T1D living in Piedmont, of Caucasian or Moroccan origin, with healthy control subjects matched for age and ethnicity. Data of resident children in Morocco, with and without T1D, were used for comparison.
RESULTS:
Caucasian (21.4±1.5 vs 24.0±0.5 ng/ml, p<0.05) and Moroccan children with T1D (12.0±2.6 vs 17.1±1.7 ng/ml, p<0.05) living in Piedmont had lower 25OHD levels than their counterparts without diabetes. Moroccan children living in Morocco with and without T1D had similar 25OHD levels. Vitamin D deficiency was associated with T1D in Caucasian and Moroccan children living in Piedmont (OR: 1.720, CI95% 1.034--2.860, p<0.03),
CONCLUSIONS: Lower vitamin D levels were associated with T1D in Piedmont. Further studies are necessary to explain a possible relationship between vitamin D and T1D.
PMID: 25604589