Table of contents
- Effect of a Nutritional Support System to Increase Survival and Reduce Mortality in Patients with COVID-19 in Stage III and Comorbidities: A Blinded Randomized Controlled Clinical Trial
- Vitamin D Life - Virus and Omega-3
- Vitamin D Life - Virus and Magnesium
- Vitamin D Life - Virus and Resveratrol (increases Receptor Activation)
- Vitamin D Life - Virus and Vitamin D Receptor
- Vitamin D Life - Virus and Zinc
- Vitamin D Life - Virus and Probiotics
- Vitamin D Life – COVID-19 treated by Vitamin D - studies, reports, videos
Effect of a Nutritional Support System to Increase Survival and Reduce Mortality in Patients with COVID-19 in Stage III and Comorbidities: A Blinded Randomized Controlled Clinical Trial
International Journal of Environmental Research and Public Health https://doi.org/10.3390/ ijerph19031172
Fernando Leal-Martínez h*, Lorena Abarca-Bernal1, Alejandra García-Pérez 1, Dinnaru González-Tolosa 1, Georgina Cruz-Cázares 1, Marco Montell-García 2 and Antonio Ibarra -1©
Centro de Investigación en Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud (FCS), Universidad Anáhuac México Norte, Mexico City 52786, Mexico; lore19.ab at gmail.com (L.A.-B.); alejandragp_ at hotmail.com (A.G.-P.); din.tolosa at gmail.com (D.G.-T.); georgina.crucaz at hotmail.com (G.C.-C.); jose.ibarra at anahuac.mx (A.I.)
Centro Médico ISSEMyM (CMI) Toluca "Lic. Arturo Montiel Rojas", Toluca City 52170, Mexico; cazabichos at yahoo.com
- Correspondence: ferman5 at hotmail.com; Tel.: +52-5521094339
The COVID-19 evolution depends on immunological capacity. The global hospital mortality rate is 15-20%, but in México it is 46%. There are several therapeutic protocols, however, integral nutrition is not considered. In this study, a Nutritional Support System (NSS) was employed to increase survival and reduce mortality in patients with stage III COVID-19. A randomized, blinded, controlled clinical trial was performed. Eighty patients (aged 30 to 75 years, both sexes) were assigned to (1) "Control Group" (CG) hospital diet and medical treatment or (2) "Intervention Group" (IG) hospital diet, medical treatment, and the NSS (vitamins, minerals, fiber, omega-3, amino acids, B- complex, and probiotics). IG significantly increased survival and reduced mortality compared to CG (p = 0.027).
IG
- decreased progression to Mechanical Ventilation Assistance (MVA) by 10%,
- reduced the intubation period by 15 days, and
- inicreased survival in intubated patients by 38% compared to CG.
IG showed improvement compared to CG in
- decrease in supplemental oxygen (p = 0.014), the
- qSOFA test (p = 0.040), constipation (p = 0.014), the
- PHQ-9 test (p = 0.003), and
- in the follow-up, saturation with oxygen (p = 0.030).
The NSS increases survival and decreases mortality in patients with stage III COVID-19.
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The IG received the NSS, which consists in:
- (1) B-complex: 10 mg of cyanocobalamin, 100 mg of thiamin, and 100 mg of pyridoxine administered intramuscularly every 24 h for the first 5 days.
- ((2) NSS powder: one envelope orally after morning meals and another after evening meals, diluted in 400 mL of water each, during the whole intervention for a maximum of 21 days. Each envelope contained:
- Spirulina Maxima 2.5 g, folic acid 5 mg,glutamine 5 g, vegetable protein 10 g, constituted by two foods without processing or fragmenting in amino acids,
- brewer’s yeast, and
- amaranth, ascorbic acid 1 g,
- zinc 20 mg,
- selenium 100 mcg,
- cholecalciferol 2000 IU,
- resveratrol 200 mg
- Omega-3 fattyacids 1 g
- L-Arginine 750 mg, inulin 20 g, and
- magnesium 400 mg.
- (3) Probiotics: Saccharomyces boulardii (SB) 500 mg daily for 6 days orally
Vitamin D Life - Virus and Omega-3
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- High-dose Omega-3 fought COVID in 2 hospital trials (6x reduction in ICU, reduced time) – Masterjohn Oct 2021
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- Omega-3 reduces risk of COVID-19 - many studies
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 and many other health problems – June 2021
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- COVID-19 Cytokine storms attenuated by Vitamin D, Omega-3, Mg, Resveratrol, etc – April 2021
- COVID-19 ICU survival rate increased 7X by daily Omega-3 – RCT March 2021
- 4X fewer COVID-19 deaths in those having high Omega-3 index – Jan 6, 2021
Vitamin D Life - Virus and Magnesium
- Long-COVID 3.1 X more likely if insufficient amounts of Magnesium and Vitamin D – March 2024
- COVID appears to be treated by many antioxidants (Vitamins D, C, E, K, and Quercetin, Curcumin, etc) – Jan 2023
- Fatigue and other long-haul problems appear to be associated with low Magnesium - Chambers Oct 2022
- Low Magnesium associated with severe COVID – many studies
- COVID and Magnesium - hypothesis, clinical trials, Long-Haul - Oct 2021
- COVID treatment patent applied for - using Rutin, Vitamin D, Vitamin C, Magnesium, etc. – April 2022
- COVID death 6.9X less likely if high Magnesium to Calcium ratio – April 2022
- Hypothesis: 2 long-haul COVIDs: had mild symptoms and had needed ICU - April 2022
- Excess Magnesium is bad for health (COVID hospital days in this case) – April 2022
- Vitamin D, Zinc, Magnesium etc. are needed to fight COVID – April 2022
- Long Covid, Short Magnesium - Chambers April 2022
- Lower Magnesium, 6 percent more COVID - Feb 2022
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 and many other health problems – June 2021
- Elderly nutrition and COVID-19 – systematic review July 2021
- Magnesium in Infectious Diseases in Older People - Jan 2021
- COVID-19 Cytokine storms attenuated by Vitamin D, Omega-3, Mg, Resveratrol, etc – April 2021
- 6X less risk of COVID-19 ICU if Vitamin D and Vit B12 and Mg – Jan 2021
- Cytokine storms (COVID-19, etc.) eliminated by Vitamin D (Magnesium helps)
- Magnesium and Vitamin D deficiencies associated with worse COVID-19 – Jan, 2021
- Excessive insulin decreases vitamin D in 4 ways – problems for diabetic COVID-19 – Dec 2020
- Magnesium (which increases vitamin D) may fight COVID-19 - Oct 2020
- COVID-19 1.8 X more likely if proton pump inhibitor (decreases Mg and Vitamin D) – Aug 2020
- COVID-19 might be treated with Mg IV and Potassium – July 2020
- COVID-19 prompts awareness of deficiencies of Vitamin D, C and Magnesium - April 6 2020
- Obesity pandemic since 1975 - is it due to Vitamin D, Magnesium, Iodine, adenovirus, or what
Vitamin D Life - Virus and Resveratrol (increases Receptor Activation)
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- COVID-19 appears reduced by Resveratrol plus 100K IU of vitamin D – Small RCT Sept 2021
- COVID-19 risk reduced 4X by each of: Vitamin D, Omega-3, Curcumin, Zinc (each increases D in cells)
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- COVID-19 Cytokine storms attenuated by Vitamin D, Omega-3, Mg, Resveratrol, etc – April 2021
- COVID-19 what it is, prevention by Functional Nutrition doctor - Feb 2021
- Vitamin D Receptor activation should reduce ARDS associated with COVID-19 - June 2020
- COVID-19 possible therapies: Vitamin D, Selenium, Zinc, Vitamin C, Potassium, Resveratrol , etc.– Aug 5, 2020
- Fight COVID-19 with Vitamin D, Vitamin C, Zinc, Selenium, Resveratrol, etc. - Sardi May 12, 2020
Vitamin D Life - Virus and Vitamin D Receptor
- COVID maximum downregulation of Vitamin D receptor and CYP27B1 resulted in death - Feb 2024
- COVID in hospital stopped by Vitamin D Receptor activators (curcumin, quercetin) – RCT June 2023
- Children with COVID 4X more likely to have poor Vitamin D Receptors (Note: COVID deactivates VDR) – April 2023
- Diabetes 3X more likely if had COVID ICU (VDR was deactivated) - April 2023
- COVID variants protect themselves by deactivating different VDR variants– March 2023
- Dengue Fever decimated by Vitamin D - many studies
- COVID kids were more likely to have a poor VDR (4.3 X), than low Vitamin D (2.6 X) – Sept 2022
- Cancers are associated with low vitamin D, poor vaccination response and perhaps poor VDR – July 2022
- COVID 3X more likely if a poor Receptor (cells get less Vitamin D from the blood) – July 2022
- Long-COVID is now the biggest COVID concern - many studies
- COVID death 12X more likely if poor Vitamin D Receptor (less D gets to cells) - many studies
- COVID severity, ICU, and mortality all associated with poor vitamin D receptor (but not D, everyone had low D) -Dec 2021
- Different Vitamin D Receptor problems cause different COVID problems - Dec 2021
- COVID-19 severity associated with 3 vitamin D genes – Oct 2021
- Poor Vitamin D receptor blocked Vitamin D from fighting avian influenza viruses (in mice) – July 2021
- Epstein-Barr is yet another virus that deactivates the Vitamin D receptor (COVID later suspected as well)– 2010
- COVID-19 symptoms and comorbidities associated with the type of Vitamin D Receptor – Oct 2021
- Enveloped virus infection (RSV, coronavirus, HIV, etc.) 1.5X more likely if poor Vitamin D Receptor – meta-analysis Dec 2018
- COVID-19 outpatients getting Quercetin nanoemulsion had excellent outcomes (Q increased Vitamin D in cells) – RCT – June 2021
- A virus that most adults have (Cytomegalovirus) decreases the amount of Vitamin D which gets to the cells – Jan 2017
- COVID virus alters the activation of 100 vitamin D related genes in the lung – April 2021
- Common sense COVID-19 risk reduction - masks, social distancing, vitamin D - Oct 2020
- AI is examining 170,000 potential COVID-19 treatments, Vitamin D is one of only 6 found – Sept 4, 2020
- Vitamin D Receptor activation should reduce ARDS associated with COVID-19 - June 2020
- Dengue viral production decreased 1000X if activate Vitamin D Receptor (in lab) – July 2020
- Vitamin D, Quercetin, and Estradiol all increase vitamin D in cells and increase genes which reduce COVID-19 – May 21, 2020
- Quercetin and Vitamin D - Allies Against COVID-19
- Risk of enveloped virus infection is increased 50 percent if poor Vitamin D Receptor - meta-analysis Dec 2018
- Hand, foot, and Mouth disease is 14X more likely if poor Vitamin D Receptor – Oct 2019
- Treating herpes reduced incidence of senile dementia by 10 X (HSV1 reduces VDR by 8X) – 2018
- Severe hand, foot, and mouth virus is 2.9 X more likely if poor Vitamin D receptor – Oct 2018
- Hepatitis B virus reduced by 5X the Vitamin D getting to liver cells in the lab – Oct 2018
- Some enveloped virus are 1.2 X more likely if have a poor Vitamin D Receptor -Aug 2018
- Severe Pertussis is 1.5 times more likely if poor vitamin D receptor – Feb 2016
- Dengue Fever associated with poor vitamin D receptor – July 2002
- Dengue virus 2X to 4X more likely if vitamin D receptor gene problems
Vitamin D Life - Virus and Zinc
- COVID was associated with low Vitamin D or Zinc – umbrella review Feb 2023
- 23 COVID mitigation strategies: at least 6 of which increase Vitamin D in cells - Sept 2022
- COVID and Zinc - many studies
- Surviving COVID with vitamins and minerals is not a myth – June 2022
- Vitamin D, Zinc, Magnesium etc. are needed to fight COVID – April 2022
- How vitamins D, C, Zinc, and Selenium might fight COVID - Dec 2021
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- COVID-19 decreased risk if add Vitamin D, A, C, NAC, Se, Zn, or Omega-3 – Dec 2021
- COVID-19 patients had low levels of Zinc, Vitamin A, Vitamin D, and Vitamin C – Sept 2021
- COVID-19 risk reduced 4X by each of: Vitamin D, Omega-3, Curcumin, Zinc (each increases D in cells)
- Vitamin D, C, A, and E, as well as Iron, Se, and Zinc each augment vaccine response – July 2021
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 and many other health problems – June 2021
- COVID-19 treatment outside of hospital – Vitamin D, zinc, etc. – May 2021
- Important Role of Micronutrients during COVID-19 (Zinc, Vitamin D, C, Folate) – May 5, 2021
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- Zinc therapy for COVID-19 – Feb 2021
- COVID-19 alternative treatments - real-time database
- Overview of reviews of COVID-19 and vitamin D, etc. – April 2021
- COVID-19 what it is, prevention by Functional Nutrition doctor - Feb 2021
- Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) - Jan 25, 2021
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
- Micronutrients for COVID-19: Vitamin D, Vitamin C, Melatonin, Zinc, Se, etc. - Dec 2020
- Zinc (which increases vitamin D in tissues) may both prevent and treat COVID-19
- COVID-19 possible therapies: Vitamin D, Selenium, Zinc, Vitamin C, Potassium, Resveratrol , etc.– Aug 5, 2020
- 7 reasons to think that Zinc should fight COVID-19 – July 2020
- Observations that Vitamin D, Zinc, and Selenium separately reduce COVID-19 – Aug 7, 2020
- Mild COVID-19 quickly treated by Zinc lozenges in 4 people – June 6, 2020
- Zinc, respiratory tract infections and COVID-19 – July 2020
- Fight COVID-19 with Vitamin D, Vitamin C, Zinc, Selenium, Resveratrol, etc. - Sardi May 12, 2020
- Common cold prevented and treated by Vitamin D, Vitamin C, Zinc, and Echinacea – review April 2018
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- Overview Colds and flu and Vitamin D
Vitamin D Life - Virus and Probiotics
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- COVID Long-Haul fought by probiotics - Jan 2022
- Tested positive for COVID, taking probiotics stopped symptoms 5 days sooner - RCT Jan 2022
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
Vitamin D Life – COVID-19 treated by Vitamin D - studies, reports, videos
As of March 31, 2024, the Vitamin D Life COVID page had: trial results, meta-analyses and reviews, Mortality studies see related: Governments, HealthProblems, Hospitals, Dark Skins, All 26 COVID risk factors are associated with low Vit D, Fight COVID-19 with 50K Vit D weekly Vaccines Take lots of Vitamin D at first signs of COVID 166 COVID Clinical Trials using Vitamin D (Aug 2023) Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
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