Association of Glycosylated Hemoglobin Levels With Vitamin D Status
J Clin Med Res. 2017 Dec; 9(12): 1013–1018. doi: 10.14740/jocmr3227w, PMCID: PMC5687907
Badurudeen Mahmood Buhary,a Ohoud Almohareb,a Naji Aljohani,a,b Saleh Alrajhi,a Samer Elkaissi,a Suphia Sherbeeni,a Abdulrahman Almaghamsi,a Shawana Abdulhamid Khan,a and Mussa H. Almalkia,b,c
Note from corresponding author
- 50,000 IU Vitamin D monthly for all groups for 9 months
- Deficient groups got an 3 additional 50,000 IU/month for the first 2 months (50,000 IU weekly)
Interestingly the HbA1C dropped similar amounts (10% ==> 8%) for those with low, medium, and good levels of vitamin D
Perspective as to what a drop from 10% to 8% means
See also Vitamin D Life
- Type 1 diabetes helped with 50,000 IU of vitamin D every two weeks – Nov 2014
HbA1C levels dropped from 9.7% to 9% - Diabetic inflammation reduced by Vitamin D – meta-analysis Feb 2018
- Diabetic glycation control is inversely related to Vitamin D in India – Feb 2015
Glycation control - Prediabetes reduced by monthly 60,000 IU of vitamin D – RCT May 2015
6% ==> 5.7%
Pages listed in BOTH the categories Diabetes and Intervention
- 4X reduction in prediabetes progressing to T2D if more than 50 ng of vitamin D – RCT March 2023
- Diabetic inflammation synergistically decreased by Vitamin D and exercise – RCT June 2022
- Diabetes prevented by 50,000 IU vitamin D monthly (Iran) – Jan 2022
- Most Diabetics getting 40,000 IU of vitamin D weekly did not get to 30 ng (needed gut-friendly form) - RCT June 2020
- Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT Aug 2021
- Little Vitamin D benefit if not achieve a good level (T1D in this cases) – Jan 2021
- Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT Jan 2021
- Diabetic inflammation reduced by Vitamin D (30,000 IU weekly) – RCT July 2020
- Diabetes not helped by increasing Vitamin D levels to 20 ng (proven again) – RCT March 2020
- Several Diabetic pains reduced by injection of 300,000 IU of Vitamin D – RCT Feb 2020
- Diabetes helped by 5,000 IU of Vitamin D – RCT Sept 2019
- 100,000 IU of Vitamin D3 monthly for 4 months to diabetics (D2 bombed) – RCT Dec 2019
- Diabetics and prediabetics helped by 5,000 IU of Vitamin D for 6 months– RCT July 2019
- Depression reduced in Diabetics with 3 months of 4,000 IU of vitamin D – RCT July 2019
- Type 2 Diabetes inflammation reduced by 50,000 IU of Vitamin D bi-weekly and resistance training – RCT – June 2019
- Vitamin D fails to prevent Type 2 Diabetes (unaware of 8 proven ways) June 2019
- Prediabetes both prevented and treated by monthly Vitamin D, etc.
- Peripheral diabetic neuropathy helped by weekly 50,000 IU vitamin D – Jan 2019
- Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT Jan 2019
- Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018
- Waist size reduced 3 cm by Vitamin D in those with Metabolic Syndrome – Jan 2017
- HbA1c levels (Diabetes) reduced by monthly 50,000 IU of vitamin D – Dec 2017
- Gestational diabetes 30 percent less likely if consumed more than 400 IU of vitamin D daily – Oct 2017
- Vitamin D injection is far better than oral for diabetics (poor gut) – RCT March 2017
- Gestational diabetes treated by Vitamin D plus Omega-3 – RCT Feb 2017
- Diabetes treated if given enough vitamin D (example: 50,000 IU weekly) – review of RCT - Jan 2017
- Gestational Diabetes reduce 3 times by 5,000 IU of Vitamin D – RCT Jan 2016
- Gestational Diabetes treated with 50,000 IU every two weeks – RCT Sept 2016
- Diabetic neuropathy reduced by injection of 600,000 IU of vitamin D – Feb 2016
- Diabetes treated by vitamin D when levels exceeded 61 ng – Sept 2015
- Prediabetes reduced by monthly 60,000 IU of vitamin D – RCT May 2015
- Diabetes decreased in aged mice supplemented with vitamin D – April 2015
- Pain of Diabetic Neuropathy reduced with weekly 50,000 IU vitamin D– CT Feb 2015
- Gestational diabetes – Vitamin D and Calcium provided huge benefits – RCT March 2015
- T1 diabetes in children helped with two doses of 150,000 IU of vitamin D and Calcium – March 2015
- Diabetic hypertension reduced with Vitamin D and Calcium – RCT March 2015
- Gestational diabetes reduced by just two 50,000 IU doses of vitamin D – RCT Nov 2014
- Type 1 diabetes helped with 50,000 IU of vitamin D every two weeks – Nov 2014
- Recent Diabetics treated by supplementation which achieved 60 ng of vitamin D – RCT Sept 2014
- Diabetic inflammation reduced by Calcium and 50,000 IU of vitamin D in 8 weeks – RCT 2014
- Gestational Diabetes reduced with 50,000 IU of vitamin D every 3 weeks and daily Calcium – RCT June 2014
- Gestational Diabetes reduced 40 percent by 5,000 IU of vitamin D – RCT April 2014
- Blood pressure in diabetics reduced by 12 weekly doses of 50,000 IU vitamin D – RCT Jan 2014
- Diabetes (Type II) reduced by single injection of 300,000 IU of vitamin D3 – RCT March 2014
- Prediabetics 60 percent less likely to become diabetic if given some vitamin D – Jan 2014
- Diabetes prevention RCT kicked off: adding 4,000 IU vitamin D - Oct 2013
- 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013
- Insulin resistance during pregnancy improved with 50,000 IU of vitamin D every 2 weeks – RCT April 2013
- Insulin improvement in obese teens with 4000 IU of vitamin D – RCT Feb 2013
- Insulin resistance helped with 50000 IU of vitamin D weekly – Feb 2013
Download the PDF from Vitamin D Life
Background
The discovery of vitamin D is one of medicine’s great achievements. Despite all the positive evidence emerging about the beneficial effect of vitamin D, we still find many are vitamin D deficient. The purposes of this study were to examine the association between serum 25-hydroxyvitamin D (25(OH)D) and glycosylated hemoglobin (HbA1c) levels, to test the hypothesis that lower 25(OH)D levels are associated with poorer glucose control in diabetes mellitus (DM) patients and to investigate the effect of vitamin D supplementation on HbA1c levels.
Methods
This was a prospective observational cohort study of all patients with type 1 and type 2 diabetes (above 12 years) who attended the outpatient clinics of a tertiary center in Riyadh. HbA1c and vitamin D levels were recorded prior to supplementation and after 9 months of supplementation with vitamin D. All patients were divided into four groups according to their vitamin D level and an association between 25(OH)D and HbA1c was tested.
Results
Results showed that 73.1% of the patients had 25(OH)D levels < 50 nmol/L. We observed lowering of HbA1c after vitamin D supplementation (from mean HbA1c of 10.55 to 7.70). We found HbA1c to be inversely related to serum vitamin D levels (r = -0.14 (P < 0.0000002) before supplementation and -0.16 (P < 0.000001) after supplementation with vitamin D).
Conclusions
Advising patients with higher HbA1c to test their vitamin D level and correct any deficiency will result in better blood glucose control and benefit the patient’s overall health.